Article(id=1304414723387183860, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.04.010, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1758124800000, receivedDateStr=2025-09-18, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926304908, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926304908, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926304908, creator=13701087609, updateTime=1788926304908, updator=13701087609, issue=Issue{id=1304414700964443026, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='4', pageStart='1209', pageEnd='1596', issueExtLink='null', onlineDate='null', pubDate='1772208000000', pubDateStr='2026-02-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926299563, creator='13701087609', updateTime=1788926573099, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304415848316297970, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304415848316297971, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1297, endPage=1310, ext={EN=ArticleExt(id=1304414723970192118, articleId=1304414723387183860, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Quality consistency evaluation of intermediates and reference samples of classic formula Qingxin Lianzi Yin based on Bizhunziwei by electronic tongue and its application in optimization of pretreatment processes, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective Avoltammetric electronic tongue was applied to establish Bizhunziwei for evaluating the quality consistency between classical formulas Qingxin Lianzi Yin (QLY, 清心莲子饮) intermediate and explore its application in the pretreatment process optimization of QLY. Methods By comprehensively analyzing the precision of Euclidean distance (Ed), mean Euclidean distance (M-Ed), and standardized Euclidean distance (S-Ed) between the taste PCA score plots of intermediates and substance benchmark in combination with the discrimination index (DI), to construct the standard taste profile. The effects of the sample’s pH value, the salt ions and redox-active substances on Bizhunziwei were studied and the precision, repeatability and stability of Bizhunziwei were investigated. The application of Bizhunziwei in the pretreatment processes of QLY such as extraction and drying of classic famous prescriptions was explored and the correlation between Bizhunziwei and the similarity of fingerprint profiles was analyzed. Results The Bizhunziwei could be defined as “S-Ed*DI” which was the product of standardized Euclidean distance and the discrimination index of the taste PCA score plots. The RSD values for the precision, repeatability and stability of Bizhunziwei were 2.355%, 5.630%, 3.573%, respectively. The sample’s pH value, the salt ions and redox-active substances had a significant impact on Bizhunziwei (P < 0.05). The Bizhunziwei could distinguish the extraction and drying process parameters of QLY. The Bizhunziwei had a good correlation with the similarity of the fingerprint profile of QLY. Conclusion The Bizhunziwei provides a new approach for evaluating the quality consistency between intermediates and substance benchmark of QLY, and offers a new perspective for the development of classic famous prescriptions., authors=YANG Huasheng, XIAO Yin, CHU Ruige, DUAN Yawen, CHEN Yufang, WU Lu, authorsList=YANG Huasheng, XIAO Yin, CHU Ruige, DUAN Yawen, CHEN Yufang, WU Lu, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304414723798225653, articleId=1304414723387183860, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=采用电子舌构建比准滋味评价经典名方清心莲子饮中间体与基准样品质量一致性及其在前处理工艺优化中的应用, columnId=1304140189132149234, journalTitle=中草药, columnName=药剂与工艺, runingTitle=null, highlight=null, articleAbstract=目的 采用伏安型电子舌构建比准滋味，以此建立评价经典名方清心莲子饮（Qingxin Lianzi Yin，QLY）中间体与其基准样品质量一致性的方法，并探索其在经典名方QLY前处理工艺中的应用。方法 综合分析中间体、基准样品的滋味主成分分析（principal component analysis，PCA）得分图之间欧氏距离（Euclidean distance，Ed）、平均欧氏距离（mean Euclidean distance，M-Ed）、标准化距离（standardized euclidean distance，S-Ed）的精密性，结合滋味PCA得分图的区分指数（discrimination index，DI），构建比准滋味；研究pH值、盐离子、氧化还原物质对比准滋味的影响，考察比准滋味的精密性、重复性、稳定性；探索比准滋味在经典名方QLY提取、干燥等前处理工艺中的应用；分析比准滋味与指纹图谱相似度的相关性。结果 S-Ed精密性好，故定义比准滋味为“S-Ed*DI”，即滋味PCA得分图的标准化距离与区分指数的乘积，其精密度、重复性、稳定性的RSD分别为2.355%、5.630%、3.573%，且样品的pH值及其含有的盐离子、氧化还原物质均对比准滋味具有显著性影响（P＜0.05）；比准滋味能区分QLY的提取、干燥工艺参数，与其指纹图谱相似度有较好的相关性。结论 比准滋味为经典名方QLY中间体与其基准样品质量一致性评价提供了新方法，为经典名方开发提供新视角。, authors=杨华生¹, 肖音¹, 楚瑞阁¹, 段亚文¹, 陈玉芳¹, 吴璐¹, authorsList=杨华生, 肖音, 楚瑞阁, 段亚文, 陈玉芳, 吴璐, authorCompany=1 江西中医药大学, 江西 南昌 330004, correspAuthors=吴璐, authorNote=杨华生: 杨华生，博士，教授，主要从事传统中医药理论及中药制剂研究。E-mail:yanghuasheng456@126.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=SHvrT4Kkqu0aLC1vlyLUQg==, pdfFileSize=2867357, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=江西省自然科学基金面上项目 (20232BAB206171); 江西省研究生创新专项资金项目 (XJ-S202483); 江西省研究生创新专项资金项目 (XJ-S202483); 中药科研实践创新训练项目 (24KYCX-YB053))}, authors=null, keywords=[Keyword(id=1304414724108604151, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414723387183860, language=CN, orderNo=1, keyword=比准滋味), Keyword(id=1304414724175713016, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414723387183860, language=CN, orderNo=2, keyword=质量一致性), Keyword(id=1304414724247016185, 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provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.04.010, detailUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/10.7501/j.issn.0253-2670.2026.04.010, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/PDF/10.7501/j.issn.0253-2670.2026.04.010, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/PDF/10.7501/j.issn.0253-2670.2026.04.010, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1788926304908, fullTextJson=null, articleText=null, reference=国家药品监督管理局. 古代经典名方中药复方制剂简化注册审批管理规定：2018年第27号公告[EB/OL]. (2018-05-29) [2025-06-02]. http://www.nmpa.gov.cn/WS04/CL2093/228247.html.
国家药品监督管理局. 按古代经典名方目录管理的中药复方制剂药学研究技术指导原则（试行）[EB/OL]. (2021-08-31) [2021-11-04]. https://www.cde.org.cn/main/news/viewInfoCommon/1c18dd163e7c9221786e5469889367d0.
刘雨涵, 关雅戈, 韩晨, 等. 经典名方桃核承气汤物质基准关键质量属性传递规律分析[J]. 中草药, 2022, 53(7): 2011-2021.
徐瑞杰, 薛蓉, 梅茜, 等. 经典名方枳实薤白桂枝汤物质基准的量值传递研究[J]. 中草药, 2022, 53(9): 2650-2658.
李婷, 邓碧莲, 欧阳征海, 等. 基于甜味受体整合中药“效味”和“滋味”探索玉竹甘味药性物质基础[J]. 中草药, 2023, 54(3): 849-858.
张雪妮, 王凯, 贾鑫, 等. 基于电子舌技术的不同来源广枣味觉信息研究[J]. 中华中医药杂志, 2023, 38(1): 376-381.
王晓宇, 郭俊霞, 吴萍, 等. 基于电子舌技术的川芎味觉信息与主要化学成分相关性研究[J]. 中药材, 2020, 43(1): 34-41.
蒋姗, 赵晓梅, 郭杰, 等. 基于有效成分及味觉变化规律的吴茱萸“汤洗”炮制工艺研究[J]. 中国中药杂志, 2023, 48(13): 3485-3497.
Gao W Y, Tian M Y, Li M L, et al. Study on the potential mechanism of Qingxin Lianzi Yin Decoction on renoprotection in db/db mice via network pharmacology and metabolomics [J]. Phytomedicine, 2024, 126: 155222.
Gao W Y, Si N, Li M L, et al. The integrated study on the chemical profiling and in vivo course to explore the bioactive constituents and potential targets of Chinese classical formula Qingxin Lianzi Yin Decoction by UHPLC-MS and network pharmacology approaches [J]. J Ethnopharmacol, 2021, 272: 113917.
尚超凡, 周巧, 朱娟娟, 等. 电子感官技术在中药质量辨识及炮制的应用概况[J]. 中草药, 2024, 55(24): 8654-8663.
戚淑叶, 毛岳忠, 耿利华, 等. 现有电子舌设备的技术现状与发展趋势[J]. 药学学报, 2023, 58(11): 3165-3172.
张爱霞. 基于差别度检验的电子舌应用方法学研究[D]. 杭州: 浙江工商大学, 2012.
Cheng S W, Qin Y M, Mao Y Z, et al. “Reference sample comparison method”: A new voltammetric electronic tongue method and its application in assessing the shelf life of fresh milk [J]. Food Chem, 2025, 463: 141064.
程时文. 基于电子舌差别度的鲜牛奶、豆奶货架期预测方法研究[D]. 杭州: 浙江工商大学, 2017.
赵玥瑛, 王昌海, 张泽康, 等. Box-Behnken设计-响应面法结合基准关联度和AHP-熵权法优化经典名方小承气汤的提取工艺[J]. 中草药, 2022, 53(20): 6472-6480.
那效旗, 田明. 清心莲子饮物质基准HPLC指纹图谱的建立[J]. 中药材, 2022, 45(7): 1679-1682.
李钰, 叶霄, 黄位年, 等. 基于指纹图谱、主成分分析及正交偏最小二乘判别分析评价不同生长年限实生芍药特征[J]. 中草药, 2025, 56(7): 2505-2517.
Ha D, Sun Q Y, Su K Q, et al. Recent achievements in electronic tongue and bioelectronic tongue as taste sensors [J]. Sens Actuat B Chem, 2015, 207: 1136-1146.
Salvo-Comino C, Martín-Bartolomé P, Pura J L, et al. Improving the performance of a bioelectronic tongue using silver nanowires: Application to milk analysis [J]. Sens Actuat B Chem, 2022, 364: 131877.
张永超, 刘佳丽, 李执栋, 等. 基于近红外光谱法和折光率法的热毒宁注射液金银花提取和浓缩工序中间体总固体量快速检测研究[J]. 中草药, 2025, 56(5): 1587-1595.)