Article(id=1304406836162093522, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.02.003, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1760630400000, receivedDateStr=2025-10-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788924424447, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788924424447, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788924424447, creator=13701087609, updateTime=1788924424447, updator=13701087609, issue=Issue{id=1304406828071281069, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='2', pageStart='393', pageEnd='788', issueExtLink='null', onlineDate='null', pubDate='1769529600000', pubDateStr='2026-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788924422518, creator='13701087609', updateTime=1788924652596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304407793138688830, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304407793138688831, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=405, endPage=413, ext={EN=ArticleExt(id=1304406836459889108, articleId=1304406836162093522, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Study on secondary metabolites of marine-derived fungi Talaromyces sp. 13-z-02, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To investigate the secondary metabolites produced by marine-derived fungi Talaromyces sp. 13-z-02 and their anti-inflammatory activities were studied. Methods The isolation and purification of compounds were performed using silica gel and ODS column chromatography, semi-preparative HPLC. And their structures were elucidated by MS and NMR analyses. The isolated compounds were evaluated for their anti-inflammatory activity in zebrafish. Results One new isochromane and eleven known compounds were isolated and identified as 8-hydroxy-6-methoxy-7-methylisochromane (1) from the fermentation broth of this strain, bacillisporin B (2), macrosporusone D (3), bacillisporin F (4), 1-epi-bacillisporin F (5), macrosporusone E and 1-epi-macrosporusone E (6), bacillisporin A (7), xenoclauxin (8), Sch 725680 (9), aculene C (10), 6-ethyl-2-hydroxy-4-methoxy-3-methylbenzaldehyde (11), 6-ethyl-2,4-dihydroxy-3-methylbenzaldehyde (12). Compounds 1 and 12 significantly reduced the migration of immune cells with the same concentration of 20 μmol/L and exhibited anti-inflammatory activity. Conclusion Compound 1 is a new isochromane, designated as talaroslisochromane. Compounds 1 and 12 showed anti-inflammatory activity., authors=XU Rui, LI Zilin, ZHENG Shengyan, WANG Jianjian, LI Jiaxun, WANG Ying, GAO Wenpeng, ZHANG Jie, HUANG Zonghong, KONG Fandong, WANG Cong, LI Peihai, authorsList=XU Rui, LI Zilin, ZHENG Shengyan, WANG Jianjian, LI Jiaxun, WANG Ying, GAO Wenpeng, ZHANG Jie, HUANG Zonghong, KONG Fandong, WANG Cong, LI Peihai, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304406836384391635, articleId=1304406836162093522, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=海洋真菌Talaromyces sp. 13-z-02次级代谢产物的研究, columnId=1304140187169214944, journalTitle=中草药, columnName=化学成分, runingTitle=null, highlight=null, articleAbstract=目的 研究海洋真菌Talaromyces sp.13-z-02的次级代谢产物及其抗炎活性。方法 采用硅胶和ODS柱色谱以及半制备液相色谱对发酵产物进行分离和纯化，并利用质谱和核磁共振等方法鉴定化合物的结构。基于斑马鱼模型对分离得到的化合物进行抗炎活性评价。结果 从Talaromyces sp.13-z-02菌株发酵液中分离鉴定了1个新的色满类化合物以及11个已知化合物，分别为8-羟基-6-甲氧基-7-甲基异色满（1）、芽孢杆菌素B（2）、大孢酮D（3）、芽孢杆菌素F（4）、1-epi-芽孢杆菌素F（5）、大孢酮E与1-epi-大孢酮E（6）、芽孢杆菌素A（7）、异克劳辛（8)、Sch 725680（9）、阿库烯C（10）、6-乙基-2-羟基-4-甲氧基-3-甲基苯甲醛（11）、6-乙基-2,4-二羟基-3-甲苯甲醛基（12）。化合物1和12在20 μmol/L时显著降低免疫细胞迁移率（P＜0.01）。结论 化合物1为新的色满类化合物，命名为篮异色满；化合物1和12具有抗炎活性。, authors=许睿¹, 李子林¹, 郑圣¹, 王见见¹, 李佳浔², 王颖¹, 高文鹏¹, 张洁¹, 黄宗宏¹, 孔凡栋¹, 王聪¹, 李培海², authorsList=许睿, 李子林, 郑圣, 王见见, 李佳浔, 王颖, 高文鹏, 张洁, 黄宗宏, 孔凡栋, 王聪, 李培海, authorCompany=1 广西民族大学化学化工学院, 林产化学与工程国家民委重点实验室, 广西林产化学与工程重点实验室, 林木生物质低碳高质利用广西高校工程研究中心, 广西 南宁 530006;
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