Article(id=1308842028453163249, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1308841897058198067, articleNumber=null, orderNo=null, doi=10.16438/j.0513-4870.2026-0380, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1775318400000, receivedDateStr=2026-04-05, revisedDate=1779292800000, revisedDateStr=2026-05-21, acceptedDate=null, acceptedDateStr=null, onlineDate=1789981856691, onlineDateStr=2026-09-21, pubDate=1783785600000, pubDateStr=2026-07-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1789981856691, onlineIssueDateStr=2026-09-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1789981856691, creator=13701087609, updateTime=1789981856691, updator=13701087609, issue=Issue{id=1308841897058198067, tenantId=1146029695717560320, journalId=1189982191388893191, year='2026', volume='61', issue='7', pageStart='2377', pageEnd='2820', issueExtLink='null', onlineDate='null', pubDate='1783785600000', pubDateStr='2026-07-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1789981825365, creator='13701087609', updateTime=1789984154811, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1308851667525792021, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1308841897058198067, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1308851667525792022, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1308841897058198067, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2641, endPage=2653, ext={EN=ArticleExt(id=1308842028641906930, articleId=1308842028453163249, tenantId=1146029695717560320, journalId=1189982191388893191, language=EN, title=Desorption electrospray ionization mass spectrometry imaging for analyzing spatial distribution and transformation of ginsenosides and lipids in steamed
Panax ginseng, columnId=1190335348761793317, journalTitle=Acta Pharmaceutica Sinica, columnName=Original Articles, runingTitle=null, highlight=null, articleAbstract=
To investigate the in-situ spatial distribution and dynamic transformation of ginsenosides and lipids during the steaming process of Panax ginseng, desorption electrospray ionization-mass spectrometry imaging (DESI-MSI) was employed to analyze the main root sections steamed for 0, 2, 4, 6, 8, and 10 h in both the positive and negative ion modes. Ginsenosides were detected using 95% methanol containing 0.1 mmol·L-1 NH4Cl as the spray solvent, while lipids were detected using methanol containing 0.01 mmol·L-1 TFA. The spray solvent flow rate was 2 μL·min-1, with X and Y pixel sizes of 200 μm and a raster speed of 500-700 μm·s-1. The results showed that, after the steaming, most macromolecular ginsenosides underwent degradation reactions such as demalonylation, deglycosylation, and deacetylation, leading to an increase in the content of rare ginsenosides. With prolonged steaming time, the signal intensity of most lipids decreased, and their distribution contours became blurred. Through multivariate statistical analysis, a total of 29 differential markers were screened and identified, including seven ginsenosides and 22 lipids, which were mainly distributed in the epidermis, cortex, and xylem, and their content changes were closely correlated with the steaming time. DESI-MSI technology can intuitively reveal the spatial distribution and dynamic transformation patterns of chemical components during the steaming process of P. ginseng, and the screened markers provide new scientific basis for studying the processing mechanisms and quality evaluation of P. ginseng.
, authors=Ya-dan ZOU, Yong-jian WANG, Fei-fei YANG, Min ZHANG, Xin ZHANG, Wen-zhi YANG
*, authorsList=Ya-dan ZOU, Yong-jian WANG, Fei-fei YANG, Min ZHANG, Xin ZHANG, Wen-zhi YANG, authorCompany=null, correspAuthors=Wen-zhi YANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=Copyright ©2026 Acta Pharmaceutica Sinica. All rights reserved., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1308842031749886209, articleId=1308842028453163249, tenantId=1146029695717560320, journalId=1189982191388893191, language=CN, title=基于解吸附电喷雾离子化质谱成像技术分析人参蒸制过程中皂苷与脂质成分的空间分布与转化规律, columnId=1190335348896011050, journalTitle=药学学报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=
为探究人参蒸制过程中皂苷及脂质类成分的原位空间分布与动态转化规律, 本研究采用解吸附电喷雾离子化质谱成像(desorption electrospray ionization-mass spectrometry imaging, DESI-MSI) 技术, 分别在正、负离子模式下对蒸制0、2、4、6、8、10 h的人参主根切片进行分析。皂苷检测采用含0.1 mmol·L-1 NH4Cl的甲醇-水(95∶5) 为喷雾溶剂, 脂质检测采用含0.01 mmol·L-1 TFA的甲醇为喷雾溶剂, 喷雾溶剂流速为2 μL·min-1, X和Y像素大小为200 μm, 光栅速度为500~700 μm·s-1。结果表明, 蒸制后人参多数大分子皂苷发生脱丙二酰基、脱糖基、脱乙酰基等降解反应, 稀有皂苷含量增加; 随蒸制时间延长, 多数脂质信号减弱、分布轮廓模糊。经多元统计分析, 共筛选鉴定出29个差异标志物, 包括7个皂苷和22个脂质, 主要分布于表皮、皮层及木质部, 其含量变化趋势与蒸制时间密切相关。DESI-MSI技术可直观揭示人参蒸制过程中化学成分的空间分布与动态转化规律, 所筛标志物为人参炮制机理研究及质量评价提供了新的科学依据。
, authors=邹雅丹, 王勇健, 杨飞飞, 张敏, 张鑫, 杨文志
*, authorsList=邹雅丹, 王勇健, 杨飞飞, 张敏, 张鑫, 杨文志, authorCompany=null, correspAuthors=杨文志, authorNote=
作者贡献:
邹雅丹、王勇健、杨飞飞负责实验实施、论文撰写与修改; 张敏、张鑫参与数据处理; 杨文志负责实验思路设计、稿件修改等工作。
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via regulating pentose phosphate pathway mediated by PI3K/AKT/mTOR signaling pathway [J]. Chin J Cancer Biother (中国肿瘤生物治疗杂志), 2025, 32: 1247-1252., articleTitle=null, refAbstract=null), Reference(id=1308842040025248071, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=5, rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=Li Z, Li XW, Ma XD, et al. Effect of ginsenoside on Rh2 compromised immunity in cyclophosphamide induced immunosuppression in rats by modulation of MagT1 expression [J]. Chin J Immunol (中国免疫学杂志), 2025, 41: 2919-2924., articleTitle=null, refAbstract=null), Reference(id=1308842040096551240, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=6, rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=Li X, Liu J, Zou TT, et al. Advances and challenges in ginseng research from 2011 to 2020: The phytochemistry, quality control, metabolism, and biosynthesis [J]. Nat Prod Rep, 2022, 39: 875-909., articleTitle=null, refAbstract=null), Reference(id=1308842040176243017, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=7, rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=Du YZ, Li XL, Zhou YM, et al. Current status and development trend of intelligent technology of Chinese medicine preparation [J]. Chin Arch Tradit Chin Med (中华中医药学刊), 2026. DOI:
https://link.cnki.net/urlid/21.1546.R.20260129.1633.006., articleTitle=null, refAbstract=null), Reference(id=1308842040251740490, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=8, rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=Yuan JB, Cao S, Li LM, et al. Research progress on processing technology and quality evaluation of Ginseng Radix et Rhizoma Rubra [J]. Chin Tradit Herb Drugs (中草药), 2024, 55: 6437-6447., articleTitle=null, refAbstract=null), Reference(id=1308842040394346827, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=9, rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=Liu W, Li W. Review on industrialization development status and prospect of
Panax ginseng processing [J]. J Jilin Agric Univ (吉林农业大学学报), 2023, 45: 639-648., articleTitle=null, refAbstract=null), Reference(id=1308842040469844300, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=10, rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=Li RR, Qin J. Guidance role of processing based on syndrome differentiation for Chinese traditional processed pieces used in TCM clinic application [J]. Chin J Exp Tradit Med Formulae (中国实验方剂学杂志), 2026. DOI:https://doi.org/10.13422/j.cnki.syfjx.20260317., articleTitle=null, refAbstract=null), Reference(id=1308842040541147469, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=11, rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=Gan JP, Xu X, Zou JF, et al. Comparative analysis of differential components in ′Zhangbang′ Aconite (Linjiang Slices) before and after processing based on QTOF and QQQ MS/MS [J]. J Instrum Anal (分析测试学报), 2026, 45: 680-690., articleTitle=null, refAbstract=null), Reference(id=1308842040604062030, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=12, rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=Qu T, Lu WJ, Li N, et al. Study on the dynamic changes of volatile components in Gardeniae fructus before and after processing (stir-fried and charred) based on HS-GC-IMS technology [J]. J Chin Med Mater (中药材), 2026. DOI:https://doi.org/10.13863/j.issn1001-4454.2026.01.014., articleTitle=null, refAbstract=null), Reference(id=1308842040671170895, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=13, rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=Zou YD, Ding MX, Wang HM, et al. Integration of ion-mobility high-resolution liquid chromatography/mass spectrometry-based untargeted metabolomics and desorption electrospray ionization-mass spectrometry imaging to unveil the ginsenosides variation induced by steaming for
Panax ginseng,
P. quinquefolius and
P. notoginseng [J]. Arab J Chem, 2024, 17: 105781., articleTitle=null, refAbstract=null), Reference(id=1308842040742474064, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=14, rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhang CE, Xu Y, Ma FZ, et al. Advances and prospects of mass spectrometry imaging technology in the research of the material basis of traditional Chinese medicine [J]. Chin J Exp Tradit Med Formulae (中国实验方剂学杂志), 2026. DOI:https://doi.org/10.13422/j.cnki.syfjx.20260206., articleTitle=null, refAbstract=null), Reference(id=1308842040876691793, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=15, rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=Jing Q, Wang HD, Li X, et al. State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants [J]. Trac-Trends Anal Chem, 2024, 179: 117878., articleTitle=null, refAbstract=null), Reference(id=1308842040943800658, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=16, rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=Ji YX, Peng MZ, Ning SQ, et al. Mass spectrometry-based imaging to investigate the distribution of metabolites in the retina of diabetic rats improved by
Panax notoginseng [J]. Acta Pharm Sin (药学学报), 2025, 60: 1515-1524., articleTitle=null, refAbstract=null), Reference(id=1308842041010909523, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=17, rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=Huang LY, Nie LX, Dong J, et al. Recent application of mass spectrometry imaging in traditional Chinese medicine [J]. Chin J Pharm Anal (药物分析杂志), 2022, 42: 1675-1689., articleTitle=null, refAbstract=null), Reference(id=1308842041082212692, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=18, rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang HD, Hong LL, Yang FF, et al. Desorption electrospray ionization-mass spectrometry imaging-based spatial metabolomics for visualizing and comparing ginsenosides and lipids among multiple parts and positions of the
Panax ginseng root [J]. J Agric Food Chem, 2024, 72: 27549-27560., articleTitle=null, refAbstract=null), Reference(id=1308842041157710165, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=19, rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=Huo MX, Zhang N, Bai D, et al. Progress and challenges of spatial metabolomics in traditional Chinese medicine research [J]. World Chin Med (世界中医药), 2025, 20: 3962-3969, 3981., articleTitle=null, refAbstract=null), Reference(id=1308842041287733590, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=20, rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang HD, Zhang L, Li XH, et al. Machine learning prediction for constructing a universal multidimensional information library of
Panax saponins (ginsenosides) [J]. Food Chem, 2024, 439: 138106., articleTitle=null, refAbstract=null), Reference(id=1308842041346453847, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=21, rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang RB, Zhang LY, Li X, et al. Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in
Panax ginseng example [J]. Plant Biotechnol J, 2025, 23: 4461-4476., articleTitle=null, refAbstract=null), Reference(id=1308842041426145624, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=22, rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=Liu Z, Xia J, Li W, et al. Degradation of protopanaxadiol-type ginsenosides with aspartic acid and antioxidant activity of Maillard reaction products [J]. Food Sci (食品科学), 2018, 39: 20-26., articleTitle=null, refAbstract=null), Reference(id=1308842041665220953, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=23, rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=Yang XW, Zhou QL, Yang YF, et al. Absorption and transport characteristics of ginseng triterpenoids from Ginseng Radix et Rhizoma Rubra water extract in a model of Caco-2 cell monolayer [J]. Chin Tradit Herb Drugs (中草药), 2021, 52: 3630-3641., articleTitle=null, refAbstract=null), Reference(id=1308842041744912730, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=24, rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang JX, Cui JR, Chen YJ, et al. Self-assembled triptolide prodrug nanovesicles loading with ginsenoside Rg3 for double-targeted therapy of pancreatic cancer [J]. Mater Today Bio, 2025, 33: 102004., articleTitle=null, refAbstract=null), Reference(id=1308842041824604507, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=25, rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=Feng SW, Li T, Wei XR, et al. The antioxidant and anti-fatigue effects of rare ginsenosides and
γ-aminobutyric acid in fermented ginseng and germinated brown rice puree [J]. Int J Mol Sci, 2024, 25: 10359., articleTitle=null, refAbstract=null), Reference(id=1308842041895907676, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=26, rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=Yang F, Ji YB, Qiu J, et al. Research progress on delivery systems of ginsenoside Rg3 [J]. Acta Pharm Sin (药学学报), 2026. DOI:https://doi.org/10.16438/j.0513-4870.2025-1236., articleTitle=null, refAbstract=null), Reference(id=1308842042122400093, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=27, rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=Zeng XB, Yin FW, Zhao GH, et al. Mechanism of color change in Antarctic krill oil during storage [J]. Food Chem, 2024, 444: 138583., articleTitle=null, refAbstract=null)], funds=null, companyList=[AuthorCompany(id=1308842032081236226, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, xref=null, ext=[AuthorCompanyExt(id=1308842032085430531, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, companyId=1308842032081236226, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China), AuthorCompanyExt(id=1308842032098013444, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, companyId=1308842032081236226, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=天津中医药大学, 现代中药创制全国重点实验室, 天津 301617)])], figs=[ArticleFig(id=1308842036397175087, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=Leh/jYchwKXNMQ1W5enIbQ==, figureFileBig=NUfpxh3G5ai4sQAJw9/Z1A==, tableContent=null), ArticleFig(id=1308842036455895344, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.1, caption=
Distribution map of different subtypes of ginsenosides in Panax ginseng steamed at different time period, figureFileSmall=Leh/jYchwKXNMQ1W5enIbQ==, figureFileBig=NUfpxh3G5ai4sQAJw9/Z1A==, tableContent=null), ArticleFig(id=1308842036665610545, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=mda5B9Zt+2LmpsMXIlpJRg==, figureFileBig=xm476lq0q5qeOaYQ69L/HQ==, tableContent=null), ArticleFig(id=1308842036728525106, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.2, caption=
Distribution map of different lipid subtypes in Panax ginseng at different steaming time under the negative ion mode. FAs: Fatty acids; SPs: Sphingolipids; GPs: Glycerophospholipids; GLs: Glycerolipids, figureFileSmall=mda5B9Zt+2LmpsMXIlpJRg==, figureFileBig=xm476lq0q5qeOaYQ69L/HQ==, tableContent=null), ArticleFig(id=1308842036791439667, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=bb4xugOCIP2D6cW7Gae/5g==, figureFileBig=HjnfJ9WBz4FpSkN6AKbk6w==, tableContent=null), ArticleFig(id=1308842036854354228, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.3, caption=
Distribution map of different lipid subtypes in Panax ginseng at different steaming time under the positive ion mode. PKs: Polyketides; STs: Sterol lipids, figureFileSmall=bb4xugOCIP2D6cW7Gae/5g==, figureFileBig=HjnfJ9WBz4FpSkN6AKbk6w==, tableContent=null), ArticleFig(id=1308842036913074485, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=qex9Hx/4upoX+cdt9G09cA==, figureFileBig=LngYFB6A1Bj6+G6CNSci3w==, tableContent=null), ArticleFig(id=1308842036971794742, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.4, caption=
Analysis chart of ginsenoside composition difference in different processing time of Panax ginseng under the negative ion mode. A: PLS-DA score plot; B: VIP plot; C: DESI-MSI images. VIP: Variable importance in projection, figureFileSmall=qex9Hx/4upoX+cdt9G09cA==, figureFileBig=LngYFB6A1Bj6+G6CNSci3w==, tableContent=null), ArticleFig(id=1308842037047292215, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=/Q6lfj6McGoGSd7wIwUTZg==, figureFileBig=ge/Q/emJTiWP3b6an9qbjA==, tableContent=null), ArticleFig(id=1308842037114401080, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.5, caption=
Analysis chart of lipid composition difference under different processing time of Panax ginseng in the negative ion mode. A: PLS-DA score plot; B: VIP plot; C: DESI-MSI images, figureFileSmall=/Q6lfj6McGoGSd7wIwUTZg==, figureFileBig=ge/Q/emJTiWP3b6an9qbjA==, tableContent=null), ArticleFig(id=1308842037277978937, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=bOC224iNTb57hDcrVCF7/g==, figureFileBig=i+fAZhKtHcEG+dBZe4nO7w==, tableContent=null), ArticleFig(id=1308842037336699194, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.6, caption=
The analysis chart of lipid composition difference under different processing time of Panax ginseng in the positive ion mode. A: PLS-DA score plot; B: VIP plot; C: DESI-MSI images, figureFileSmall=bOC224iNTb57hDcrVCF7/g==, figureFileBig=i+fAZhKtHcEG+dBZe4nO7w==, tableContent=null), ArticleFig(id=1308842037399613755, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=CK2wlRcgBeECdsEL6B/R4Q==, figureFileBig=Ls6pG7kfbRyahAdUEK05Sg==, tableContent=null), ArticleFig(id=1308842037466722620, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Fig.7, caption=
Transformation network diagram of ginsenoside components under different steaming time of Panax ginseng in negative ion mode, figureFileSmall=CK2wlRcgBeECdsEL6B/R4Q==, figureFileBig=Ls6pG7kfbRyahAdUEK05Sg==, tableContent=null), ArticleFig(id=1308842037546414397, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| Type | Marker | Differential component | Content variation trend with increasing steaming time |
| Seven differential saponin markers | Marker 1 | Vinaginsenoside R12 | Decrease |
| Marker 2 | Vinaginsenoside R21 (24S/R) | Decrease |
| Marker 3 | Chikusetsusaponin IVa butyl ester | Decrease |
| Marker 4 | Chikusetsusaponin IVa | Decrease |
| Marker 5 | Ginsenoside Rh4/Rk3/Rh16 | Increase |
| Marker 6 | 6′-O-Acetyl-ginsenoside Rg1 (or isomer) | Decrease |
| Marker 7 | Ginsenoside Rh26 | Decrease |
| Eleven differential lipid markers in negative ion mode | Marker 1 | 10, 13-Octadecadienoic acid (or isomer) | Decrease |
| Marker 2 | PA (12:0/22:2(13Z, 16Z)) (or isomer) | Decrease |
| Marker 3 | Palatinose | Increase |
| Marker 4 | Palmitic acid (or isomer) | Decrease |
| Marker 5 | PA (14:0/22:4(7Z, 10Z, 13Z, 16Z)) (or isomer) | Decrease |
| Marker 6 | 13-Keto-9Z-octadecenoic acid (or isomer) | Decrease |
| Marker 7 | Stearic acid (or isomer) | Decrease |
| Marker 8 | 9Z-Octadecenedioic acid (or isomer) | Decrease |
| Marker 9 | 10Z-Hexadecenyl acetate (or isomer) | Decrease |
| Marker 10 | 16-Methyl-6Z, 9Z, 12Z-heptadecatrienoic acid (or isomer) | Decrease |
| Marker 11 | 3b, 16a-Dihydroxyandrostenone sulfate (or isomer) | Increase |
| Eleven differential lipid markers in positive ion mode | Marker 1 | TG (15:1(9Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso3] (or isomer) | Decrease |
| Marker 2 | PA (P-16:0/16:1(9Z)) (or isomer) | Decrease |
| Marker 3 | PA (O-16:0/18:4(6Z, 9Z, 12Z, 15Z)) (or isomer) | Decrease |
| Marker 4 | TG (12:0/22:3(10Z, 13Z, 16Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 5 | TG (12:0/20:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 6 | TG (12:0/18:0/22:4(7Z, 10Z, 13Z, 16Z))[iso6] (or isomer) | Decrease |
| Marker 7 | DG (14:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z)/0:0)[iso2] (or isomer) | Decrease |
| Marker 8 | TG (12:0/20:1(11Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 9 | Dehydrophytosphingosine (or isomer) | Decrease |
| Marker 10 | PC (O-22:2(13Z, 16Z)/22:3(10Z, 13Z, 16Z)) (or isomer) | Decrease |
| Marker 11 | PI (13:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) (or isomer) | Increase |
), ArticleFig(id=1308842037634494782, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Tab.1, caption=
The list of differential markers of ginsenoside and lipid in different processing time of Panax ginseng
, figureFileSmall=null, figureFileBig=null, tableContent=
| Type | Marker | Differential component | Content variation trend with increasing steaming time |
| Seven differential saponin markers | Marker 1 | Vinaginsenoside R12 | Decrease |
| Marker 2 | Vinaginsenoside R21 (24S/R) | Decrease |
| Marker 3 | Chikusetsusaponin IVa butyl ester | Decrease |
| Marker 4 | Chikusetsusaponin IVa | Decrease |
| Marker 5 | Ginsenoside Rh4/Rk3/Rh16 | Increase |
| Marker 6 | 6′-O-Acetyl-ginsenoside Rg1 (or isomer) | Decrease |
| Marker 7 | Ginsenoside Rh26 | Decrease |
| Eleven differential lipid markers in negative ion mode | Marker 1 | 10, 13-Octadecadienoic acid (or isomer) | Decrease |
| Marker 2 | PA (12:0/22:2(13Z, 16Z)) (or isomer) | Decrease |
| Marker 3 | Palatinose | Increase |
| Marker 4 | Palmitic acid (or isomer) | Decrease |
| Marker 5 | PA (14:0/22:4(7Z, 10Z, 13Z, 16Z)) (or isomer) | Decrease |
| Marker 6 | 13-Keto-9Z-octadecenoic acid (or isomer) | Decrease |
| Marker 7 | Stearic acid (or isomer) | Decrease |
| Marker 8 | 9Z-Octadecenedioic acid (or isomer) | Decrease |
| Marker 9 | 10Z-Hexadecenyl acetate (or isomer) | Decrease |
| Marker 10 | 16-Methyl-6Z, 9Z, 12Z-heptadecatrienoic acid (or isomer) | Decrease |
| Marker 11 | 3b, 16a-Dihydroxyandrostenone sulfate (or isomer) | Increase |
| Eleven differential lipid markers in positive ion mode | Marker 1 | TG (15:1(9Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso3] (or isomer) | Decrease |
| Marker 2 | PA (P-16:0/16:1(9Z)) (or isomer) | Decrease |
| Marker 3 | PA (O-16:0/18:4(6Z, 9Z, 12Z, 15Z)) (or isomer) | Decrease |
| Marker 4 | TG (12:0/22:3(10Z, 13Z, 16Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 5 | TG (12:0/20:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 6 | TG (12:0/18:0/22:4(7Z, 10Z, 13Z, 16Z))[iso6] (or isomer) | Decrease |
| Marker 7 | DG (14:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z)/0:0)[iso2] (or isomer) | Decrease |
| Marker 8 | TG (12:0/20:1(11Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] (or isomer) | Decrease |
| Marker 9 | Dehydrophytosphingosine (or isomer) | Decrease |
| Marker 10 | PC (O-22:2(13Z, 16Z)/22:3(10Z, 13Z, 16Z)) (or isomer) | Decrease |
| Marker 11 | PI (13:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) (or isomer) | Increase |
), ArticleFig(id=1308842039337382207, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| No. | Component name | Abbreviation | Adduct | tR | MS/MS | VIP |
| [M‒H]‒ | [M+HCOO]‒ | [M+Cl]‒ |
| 1 | Chikusetsusaponin IVa or its isomer | Chikusetsusaponin IVa (or isomer) | 793.438 0 | / | / | 33.48 | 793.442 8, 613.378 9,
569.387 5, 523.382 9,
455.356 0 | 2.40 |
| 2 | Vinaginsenoside R12 or its isomer | Vina-R12 (or isomer) | 671.437 1 | / | / | / | / | 4.32 |
| 3 | Vinaginsenoside R21 or its isomer | Vina-R21 (or isomer) | 833.489 9 | / | / | / | / | 3.37 |
| 4 | Chikusetsusaponin IVa butyl ester or its isomer | Chikusetsusaponin IVa butyl ester (or isomer) | / | / | 885.476 8 | 14.67 | 619.425 2, 457.371 4 | 2.79 |
| 5 | 6′-O-Acetyl-ginsenoside Rg1 or its isomer | 6′-O-Ace-Rg1 (or isomer) | 841.495 0 | / | / | 10.90 | 781.474 7, 637.432 6,
619.422 9, 529.394 1,
475.379 9 | 2.25 |
| 6 | Ginsenoside Rh26 or its isomer | Rh26 (or isomer) | 1 013.568 5 | / | / | 31.71 | 785.502 0, 779.461 1,
605.437 0 | 2.08 |
| 7 | Ginsenoside Rh4/Rk3/Rh16 or its isomer | Rh4/Rk3/Rh16 (or isomer) | / | / | 655.397 7 | 38.33 | 381.233 6, 281.249 0 | 2.38 |
), ArticleFig(id=1308842039412879680, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Tab.2, caption=
Characterization information table of ginsenoside ions at different steaming times based on UPLC/Vion IM-QTOF-MS
, figureFileSmall=null, figureFileBig=null, tableContent=
| No. | Component name | Abbreviation | Adduct | tR | MS/MS | VIP |
| [M‒H]‒ | [M+HCOO]‒ | [M+Cl]‒ |
| 1 | Chikusetsusaponin IVa or its isomer | Chikusetsusaponin IVa (or isomer) | 793.438 0 | / | / | 33.48 | 793.442 8, 613.378 9,
569.387 5, 523.382 9,
455.356 0 | 2.40 |
| 2 | Vinaginsenoside R12 or its isomer | Vina-R12 (or isomer) | 671.437 1 | / | / | / | / | 4.32 |
| 3 | Vinaginsenoside R21 or its isomer | Vina-R21 (or isomer) | 833.489 9 | / | / | / | / | 3.37 |
| 4 | Chikusetsusaponin IVa butyl ester or its isomer | Chikusetsusaponin IVa butyl ester (or isomer) | / | / | 885.476 8 | 14.67 | 619.425 2, 457.371 4 | 2.79 |
| 5 | 6′-O-Acetyl-ginsenoside Rg1 or its isomer | 6′-O-Ace-Rg1 (or isomer) | 841.495 0 | / | / | 10.90 | 781.474 7, 637.432 6,
619.422 9, 529.394 1,
475.379 9 | 2.25 |
| 6 | Ginsenoside Rh26 or its isomer | Rh26 (or isomer) | 1 013.568 5 | / | / | 31.71 | 785.502 0, 779.461 1,
605.437 0 | 2.08 |
| 7 | Ginsenoside Rh4/Rk3/Rh16 or its isomer | Rh4/Rk3/Rh16 (or isomer) | / | / | 655.397 7 | 38.33 | 381.233 6, 281.249 0 | 2.38 |
), ArticleFig(id=1308842039488377153, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| Type | Component name | Abbreviation | m/z | Adduct | MS/MS | VIP |
| PKs | 5, 7-Dihydroxy-3′, 4′-dimethoxy-6, 8-dimethylflavone or its isomer | 5, 7-Dihydroxy-3′, 4′-dimethoxy-6, 8-dimethylflavone (or isomer) | 381.079 3 | [M+K]+ | 381.079 3, 365.105 3, 203.052 1, 152.071 0 | 5.40 |
| GPs | PI(13:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) or its isomer | PI 35:6 (or isomer) | 823.486 9 | [M+H‒H2O]+ | 823.486 1, 807.518 0, 675.353 4, 405.351 4 | 2.51 |
| PA(P-16:0/16:1(9Z)) or its isomer | PA O-32:2 (or isomer) | 631.469 7 | [M+H]+ | / | 4.54 |
| PA(O-16:0/18:4(6Z, 9Z, 12Z, 15Z)) or its isomer | PA O-34:4 (or isomer) | 655.473 3 | [M+H]+ | / | 4.24 |
| PC(O-22:2(13Z, 16Z)/22:3(10Z, 13Z, 16Z)) or its isomer | PC O-44:5 (or isomer) | 895.720 0 | [M+NH4]+ | / | 2.54 |
| SPs | Dehydrophytosphingosine or its isomer | SPB 18:1;O3 (or isomer) | 316.284 9 | [M+H]+ | 316.284 8, 298.274 3, 280.263 5, 262.252 9, 135.116 7 | 2.90 |
| GLs | TG(12:0/22:3(10Z, 13Z, 16Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 56:9 (or isomer) | 901.727 7 | [M+H]+ | 901.728 1, 879.745 8, 599.504 1, 397.379 6 | 3.64 |
| TG(12:0/20:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 54:5 (or isomer) | 919.712 2 | [M+K]+ | 874.701 4, 683.639 1, 600.507 9, 595.472 1, 449.344 2, 337.274 1 | 3.37 |
| TG(12:0/18:0/22:4(7Z, 10Z, 13Z, 16Z))[iso6] or its isomer | TG 52:4 (or isomer) | 893.725 4 | [M+K]+ | 893.727 1, 710.670 6, 613.493 4, 599.504 3, 574.491 1 | 3.19 |
| DG(14:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z)/0:0)[iso2] or its isomer | DG 36:5 (or isomer) | 615.499 0 | [M+H]+ | 615.498 8, 598.491 4, 523.453 1, 335.264 2 | 2.92 |
| TG(12:0/20:1(11Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 54:7 (or isomer) | 877.729 7 | [M+H]+ | 851.713 8, 683.638 6, 600.508 5, 551.494 4 | 2.90 |
| TG(15:1(9Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso3] or its isomer | TG 59:13 (or isomer) | 917.701 3 | [M+H‒H2O]+ | 899.713 5, 880.750 7, 712.669 9, 614.487 4, 576.507 5 | 4.92 |
| FAs | Stearic acid or its isomer | FA 18:0 (or isomer) | 283.262 0 | [M‒H]‒ | 283.263 4 | 3.89 |
| 9Z-Octadecenedioic acid or its isomer | FA 18:2;O2 (or isomer) | 311.221 3 | [M‒H]‒ | 311.222 7, 293.211 8, 275.200 9, 211.134 2, 171.101 7 | 3.61 |
| Palmitic acid or its isomer | FA 16:0 (or isomer) | 255.232 8 | [M‒H]‒ | 255.231 9, 237.225 7 | 5.37 |
| 10, 13-Octadecadienoic acid or its isomer | FA 18:2 (or isomer) | 279.231 9 | [M‒H]‒ | 279.231 8, 273.139 0, 261.221 4 | 11.74 |
| 10Z-Hexadecenyl acetate or its isomer | SFE 18:1 (or isomer) | 281.248 6 | [M‒H]‒ | 281.247 7 | 3.49 |
| 16-Methyl-6Z, 9Z, 12Z-heptadecatrienoic acid or its isomer | FA 18:3 (or isomer) | 277.216 8 | [M‒H]‒ | 277.216 3 | 3.39 |
| 13-Keto-9Z-octadecenoic acid or or its isomer | FA 18:2;O (or isomer) | 295.227 9 | [M‒H]‒ | 295.227 3, 277.216 6, 171.102 3 | 3.94 |
| PA(12:0/22:2(13Z, 16Z)) or its isomer | PA 34:2 (or isomer) | 671.465 7 | [M‒H]‒ | 631.382 0, 417.238 5 | 7.37 |
| GPs | PA(14:0/22:4(7Z, 10Z, 13Z, 16Z)) or its isomer | PA 36:4 (or isomer) | 695.462 5 | [M‒H]‒ | 695.465 2, 672.468 1, 409.234 9, 253.215 9 | 4.92 |
| STs | 3b, 16a-Dihydroxyandrostenone sulfate or its isomer | ST 19:2;O3;S (or isomer) | 429.158 9 | [M+TFA‒H]‒ | 429.158 6, 393.138 8, 375.126 6, 293.003 | 2.12 |
| Others | Palatinose | Palatinose | 455.103 6 | [M+TFA‒H]‒ | 279.232 1 | 7.12 |
), ArticleFig(id=1308842039568068930, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1308842028453163249, language=CN, label=Tab.3, caption=
Characterization information table of ginseng lipid differential ions at different steaming times based on UPLC/Vion IM-QTOF-MS
, figureFileSmall=null, figureFileBig=null, tableContent=
| Type | Component name | Abbreviation | m/z | Adduct | MS/MS | VIP |
| PKs | 5, 7-Dihydroxy-3′, 4′-dimethoxy-6, 8-dimethylflavone or its isomer | 5, 7-Dihydroxy-3′, 4′-dimethoxy-6, 8-dimethylflavone (or isomer) | 381.079 3 | [M+K]+ | 381.079 3, 365.105 3, 203.052 1, 152.071 0 | 5.40 |
| GPs | PI(13:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) or its isomer | PI 35:6 (or isomer) | 823.486 9 | [M+H‒H2O]+ | 823.486 1, 807.518 0, 675.353 4, 405.351 4 | 2.51 |
| PA(P-16:0/16:1(9Z)) or its isomer | PA O-32:2 (or isomer) | 631.469 7 | [M+H]+ | / | 4.54 |
| PA(O-16:0/18:4(6Z, 9Z, 12Z, 15Z)) or its isomer | PA O-34:4 (or isomer) | 655.473 3 | [M+H]+ | / | 4.24 |
| PC(O-22:2(13Z, 16Z)/22:3(10Z, 13Z, 16Z)) or its isomer | PC O-44:5 (or isomer) | 895.720 0 | [M+NH4]+ | / | 2.54 |
| SPs | Dehydrophytosphingosine or its isomer | SPB 18:1;O3 (or isomer) | 316.284 9 | [M+H]+ | 316.284 8, 298.274 3, 280.263 5, 262.252 9, 135.116 7 | 2.90 |
| GLs | TG(12:0/22:3(10Z, 13Z, 16Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 56:9 (or isomer) | 901.727 7 | [M+H]+ | 901.728 1, 879.745 8, 599.504 1, 397.379 6 | 3.64 |
| TG(12:0/20:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 54:5 (or isomer) | 919.712 2 | [M+K]+ | 874.701 4, 683.639 1, 600.507 9, 595.472 1, 449.344 2, 337.274 1 | 3.37 |
| TG(12:0/18:0/22:4(7Z, 10Z, 13Z, 16Z))[iso6] or its isomer | TG 52:4 (or isomer) | 893.725 4 | [M+K]+ | 893.727 1, 710.670 6, 613.493 4, 599.504 3, 574.491 1 | 3.19 |
| DG(14:0/22:5(7Z, 10Z, 13Z, 16Z, 19Z)/0:0)[iso2] or its isomer | DG 36:5 (or isomer) | 615.499 0 | [M+H]+ | 615.498 8, 598.491 4, 523.453 1, 335.264 2 | 2.92 |
| TG(12:0/20:1(11Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso6] or its isomer | TG 54:7 (or isomer) | 877.729 7 | [M+H]+ | 851.713 8, 683.638 6, 600.508 5, 551.494 4 | 2.90 |
| TG(15:1(9Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z))[iso3] or its isomer | TG 59:13 (or isomer) | 917.701 3 | [M+H‒H2O]+ | 899.713 5, 880.750 7, 712.669 9, 614.487 4, 576.507 5 | 4.92 |
| FAs | Stearic acid or its isomer | FA 18:0 (or isomer) | 283.262 0 | [M‒H]‒ | 283.263 4 | 3.89 |
| 9Z-Octadecenedioic acid or its isomer | FA 18:2;O2 (or isomer) | 311.221 3 | [M‒H]‒ | 311.222 7, 293.211 8, 275.200 9, 211.134 2, 171.101 7 | 3.61 |
| Palmitic acid or its isomer | FA 16:0 (or isomer) | 255.232 8 | [M‒H]‒ | 255.231 9, 237.225 7 | 5.37 |
| 10, 13-Octadecadienoic acid or its isomer | FA 18:2 (or isomer) | 279.231 9 | [M‒H]‒ | 279.231 8, 273.139 0, 261.221 4 | 11.74 |
| 10Z-Hexadecenyl acetate or its isomer | SFE 18:1 (or isomer) | 281.248 6 | [M‒H]‒ | 281.247 7 | 3.49 |
| 16-Methyl-6Z, 9Z, 12Z-heptadecatrienoic acid or its isomer | FA 18:3 (or isomer) | 277.216 8 | [M‒H]‒ | 277.216 3 | 3.39 |
| 13-Keto-9Z-octadecenoic acid or or its isomer | FA 18:2;O (or isomer) | 295.227 9 | [M‒H]‒ | 295.227 3, 277.216 6, 171.102 3 | 3.94 |
| PA(12:0/22:2(13Z, 16Z)) or its isomer | PA 34:2 (or isomer) | 671.465 7 | [M‒H]‒ | 631.382 0, 417.238 5 | 7.37 |
| GPs | PA(14:0/22:4(7Z, 10Z, 13Z, 16Z)) or its isomer | PA 36:4 (or isomer) | 695.462 5 | [M‒H]‒ | 695.465 2, 672.468 1, 409.234 9, 253.215 9 | 4.92 |
| STs | 3b, 16a-Dihydroxyandrostenone sulfate or its isomer | ST 19:2;O3;S (or isomer) | 429.158 9 | [M+TFA‒H]‒ | 429.158 6, 393.138 8, 375.126 6, 293.003 | 2.12 |
| Others | Palatinose | Palatinose | 455.103 6 | [M+TFA‒H]‒ | 279.232 1 | 7.12 |
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