Article(id=1220655370847043762, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1220655362521351042, articleNumber=null, orderNo=null, doi=10.16438/j.0513-4870.2020-0035, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1578585600000, receivedDateStr=2020-01-10, revisedDate=1592928000000, revisedDateStr=2020-06-24, acceptedDate=null, acceptedDateStr=null, onlineDate=1768956519090, onlineDateStr=2026-01-21, pubDate=1594483200000, pubDateStr=2020-07-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1768956519090, onlineIssueDateStr=2026-01-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1768956519090, creator=13701087609, updateTime=1768956519090, updator=13701087609, issue=Issue{id=1220655362521351042, tenantId=1146029695717560320, journalId=1189982191388893191, year='2020', volume='55', issue='7', pageStart='1357', pageEnd='1706', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1768956517105, creator=13701087609, updateTime=1768957228011, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1220658344335950505, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1220655362521351042, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1220658344335950506, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1220655362521351042, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1573, endPage=1589, ext={EN=ArticleExt(id=1220655371383914715, articleId=1220655370847043762, tenantId=1146029695717560320, journalId=1189982191388893191, language=EN, title=Research progress of P450 in the biosynthesis of bioactive compound of medicinal plants, columnId=1190335348648547107, journalTitle=Acta Pharmaceutica Sinica, columnName=Reviews, runingTitle=null, highlight=null, articleAbstract=

Most of the active ingredients of herbs are secondary metabolites of plants. Cytochrome P450s (P450s) are hemoglobin-containing monooxygenases encoded by a super-gene family, which play important roles in the metabolic network of plants. This review focuses on the role of P450s on biosynthesis of secondary metabolites such as terpenoids, alkaloids, flavonoids and phenylpropanoids. This will provide references for biosynthesis and regulation of secondary metabolites in medicinal plants.

, correspAuthors=Juan GUO, Lu-qi HUANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=Copyright ©2020 Acta Pharmaceutica Sinica. All rights reserved., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Ying MA, Yuan CAI, Xiao-jing MA, Guang-hong CUI, Jin-fu TANG, Wen ZENG, Shui-han ZHANG, Juan GUO, Lu-qi HUANG), CN=ArticleExt(id=1220655372751257966, articleId=1220655370847043762, tenantId=1146029695717560320, journalId=1189982191388893191, language=CN, title=药用植物活性成分生物合成中P450的研究进展, columnId=1190335349655180086, journalTitle=药学学报, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

药用活性成分多来源于药用植物次生代谢产物，是其发挥药效的物质基础。细胞色素P450s（cytochrome P450s，P450s）是一类分布广泛、由超基因家族编码的含血红色素的单加氧酶，在植物的代谢网络中发挥重要作用。本文以熟知的几类药用植物活性成分为对象，对其生物合成途径中P450相关功能进行介绍，通过对P450在萜类、生物碱、黄酮以及苯丙烷类等常见药用植物活性成分生物合成中的功能进行综述，为药用植物次生代谢产物的生物合成及调控研究提供参考。

, correspAuthors=郭娟, 黄璐琦, authorNote=null, correspAuthorsNote=, copyrightStatement=版权所有©《药学学报》编辑部2020, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=eQENsCgFQO5OE19mIlnQhQ==, magXml=l9bVrBGOsYiOs+tH3oAEnA==, pdfUrl=null, pdf=e1hfMOT6JwS5SCXy2O+Rdw==, pdfFileSize=1195178, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=4UFSLEVgt9lm5Ruymx6ODg==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=AP4aAK3kCgwm9YqZ/+mraQ==, mapNumber=null, authorCompany=null, fund=null, authors=, authorsList=马莹, 蔡媛, 马晓晶, 崔光红, 唐金富, 曾雯, 张水寒, 郭娟, 黄璐琦)}, authors=[Author(id=1220655373309100460, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1220655373468484021, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, authorId=1220655373309100460, language=EN, stringName=Ying MA, firstName=Ying, middleName=null, lastName=MA, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=1. 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Plant	Gene	Function	GeneBank ID
Mentha haplocalyx Briq.	CYP71D13	(-)-(4S)-Limonene-3-hydroxylase	Q9XHE7.1
	CYP71D15	(-)-(4S)-Limonene-3-hydroxylase	Q9XHE6.1
	CYP71D18	(-)-(4S)-Limonene-6-hydroxylase	Q9XHE8.1
Perilla frutescens	CYP71D174	(-)-Limonene-7-hydroxylase	ADC94830.1
Gossypium arboreum	CYP706B1	(+)-δ-Cadinene-8-hydroxylase	AAK60517.1
Callitropsis nootkatensis	CYP706M1	Valencene-2-oxidase	AGJ03150.1
Artemisia annua	CYP71AV1	Amorpha-4, 11-diene-12 oxidase	BAM68819.1
Cynara cardunculus var.scolymus	CYP71AV9	Costunolide synthase	AIA09040.1
Mucuna pruriens	CYP71D55	Premnaspirodiene oxygenase	RDY12970.1
Coleus forskohlii	CYP71D381	13R-Manoyloxidase	KT382342
	CYP76AH8-11		KT382346-KT382349,
	CYP76AH15-17		KT382358-KT382360
Euphorbia lathyris	CYP71D445	Casbene-9-oxidase	KR350668
	CYP726A27	Casbene-5-oxidase	KR350669
Ginkgo biloba	CYP716B	Taxoid-9a-hydroxylase	KF773141
	CYP701A	ent-Kaurene oxidase	JF929910
Jatropha curcas	CYP726A35	Casbene-5, 6-oxidase	KX060558
	CYP71D495	Casbene-9-oxidase	KX060559
Ricinus communis	CYP726A14, 17-18	Casbene-5-oxidase	KF986810, KF986813, KF986814
	CYP726A16	5-Keto-casbene-7, 8-epoxidase	KF986812
	CYP726A15	Neocembrene-5-oxidation	KF986811
Rosmariuns officinalis	CYP76AH22/23	Ferruginol synthase	KP091843/KP091844
	CYP76AH4	Ferruginol synthase	[53]
	CYP76AK7/8	11-Hydroxyferruginol-20-oxidase	KX431219/KX431220
Salvia fruticosa	CYP76AH24	Ferruginol synthase/Ferruginol-11-hydroxylase	KP091842
Salvia miltiorrhiza	CYP76AK6	11-Hydroxyferruginol-20-oxidase	KX431218
	CYP76AH1	Ferruginol synthase	JX422213
Salvia fruticosa	CYP76AH3	Ferruginol/sugiol-11-hydroxylase	KR140168
	CYP76AK1	11-Hydroxyferruginol-20-hydroxylase	KR140169
Salvia miltiorrhiza	CYP701A	ent-Kaurene oxidase	KJ606394
Salvia pomifera	CYP71BE52	Ferruginol-2-synthase	KT157042
	CYP76AH24	Ferruginol synthase/Ferruginol-11-hydroxylase	KT157044
	CYP76AK6	11-Hydroxyferruginol-20-oxidase	KT157045
Stevia rebaudiana	CYP701A5	ent-Kaurene oxidase	AY364317
Taxus canadensis	CYP725A6	Taxoid 2α-hydroxylase	AY518383
Taxus cuspidata	CYP725A1	5α-Taxadienol-10β-hydroxylase	AF318211
Stevia rebaudiana	CYP725A2	Taxane 13α-hydroxylase	AY056019
Taxus canadensis	CYP725A3	Taxane-14β-hydroxylase	AY188177
Taxus cuspidata	CYP725A4	Taxadiene-5 α-hydroxylase	AY289209
Vitex agnus-castus	CYP725A5	Taxoid-7β-hydroxylase	AY307951
Lotus corniculatus L.	CYP76BK1	Peregrinol-16-hydroxylase	MG696754.1
Catharanthus roseusd	CYP71D353	20-Hydroxylupeol-28-oxidase	AHB62239.1
	CYP716AL1	β-Amyrin-28-hydroxylase	AEX07773.1
Bupleurum roots	CYP716Y1	β-Amyrin-16-hydroxylase	AHF45909.1
Glycyrrhizae uralesis	CYP88D6	β-Amyrin-11-oxidase	QBC36431.1
Catharanthus roseusd	CYP93E3	β-Amyrin-24-hydroxylase	BAG68930.1
Bupleurum roots	CYP72A154	β-Amyrin-30-oxidase	H1A988.1
Medicago truncatula	CYP93E2	β-Amyrin-24-hydroxylase	ABC59085.1
	CYP716A12	α, β-Amyrin-28-oxidase	ABC59076.1
	CYP72A63	β-Amyrin-30-hydroxylase	H1A981.1
Medicago truncatula	CYP72A68v2	β-Amyrin-23-hydroxylase	BAL45204.1
Panax ginseng	CYP93E2	β-Amyrin-24-hydroxylase	ABC59085.1
	CYP716A12	β-Amyrin-28-oxidase	ABC59076.1
	CYP716A52v2	β-Amyrin-28-oxidase	AFO63032.1
	CYP716A47	Dammarenediol-12-hydroxylase	AEY75212.1
	CYP716A53v2	Protopanaxadiol-6-hydroxylase	I7CT85.1
Platycodon grandiflorus	CYP716A140	β-Amyrin-28-oxidase	AOG74836.1
	CYP716A141	Dammarenediol-12-hydroxylase	AOG74838.1
	CYP716S5	Oleanolic acid-12, 13α-epoxidase	AOG74839.1
Centella asiatica	CYP716A83/86	β-Amyrin-28-oxidase	AOG74832/AOG74831
	CYP716E41	Oleanolic acid-6β-oxidase	AOG74834.1
	CYP716C11	Oleanolic acid-2α-oxidase	AOG74835.1
Veratrum californicum	CYP90B27v1	Cholesterol-22-hydroxylase	KJ869252
	CYP90G1	22-Hydroxy-26-aminocholesterol-22-oxidase	KJ869260
	CYP94N1	22-Hydroxycholesterol-26-oxidase	KJ869255
Ajuga reptans	CYP71D443	Cholesterol-22-hydroxylase	BAS30379.1
Paris polyphylla	CYP90B27	Cholesterol-22-hydroxylase	KX904822
	CYP90G4	Cholesterol-5, 6-spiroketaloxidase	QDS03628
Trigonella foenum-graecum	CYP90B50	Cholesterol-5, 6-spiroketaloxidase	QDS03633.1

), ArticleFig(id=1220655378287739681, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, language=CN, label=Table 1, caption=

P450s involved in biosynthesis of terpenoids and steroidsin medicinal plants

, figureFileSmall=null, figureFileBig=null, tableContent=

Plant	Gene	Function	GeneBank ID
Mentha haplocalyx Briq.	CYP71D13	(-)-(4S)-Limonene-3-hydroxylase	Q9XHE7.1
	CYP71D15	(-)-(4S)-Limonene-3-hydroxylase	Q9XHE6.1
	CYP71D18	(-)-(4S)-Limonene-6-hydroxylase	Q9XHE8.1
Perilla frutescens	CYP71D174	(-)-Limonene-7-hydroxylase	ADC94830.1
Gossypium arboreum	CYP706B1	(+)-δ-Cadinene-8-hydroxylase	AAK60517.1
Callitropsis nootkatensis	CYP706M1	Valencene-2-oxidase	AGJ03150.1
Artemisia annua	CYP71AV1	Amorpha-4, 11-diene-12 oxidase	BAM68819.1
Cynara cardunculus var.scolymus	CYP71AV9	Costunolide synthase	AIA09040.1
Mucuna pruriens	CYP71D55	Premnaspirodiene oxygenase	RDY12970.1
Coleus forskohlii	CYP71D381	13R-Manoyloxidase	KT382342
	CYP76AH8-11		KT382346-KT382349,
	CYP76AH15-17		KT382358-KT382360
Euphorbia lathyris	CYP71D445	Casbene-9-oxidase	KR350668
	CYP726A27	Casbene-5-oxidase	KR350669
Ginkgo biloba	CYP716B	Taxoid-9a-hydroxylase	KF773141
	CYP701A	ent-Kaurene oxidase	JF929910
Jatropha curcas	CYP726A35	Casbene-5, 6-oxidase	KX060558
	CYP71D495	Casbene-9-oxidase	KX060559
Ricinus communis	CYP726A14, 17-18	Casbene-5-oxidase	KF986810, KF986813, KF986814
	CYP726A16	5-Keto-casbene-7, 8-epoxidase	KF986812
	CYP726A15	Neocembrene-5-oxidation	KF986811
Rosmariuns officinalis	CYP76AH22/23	Ferruginol synthase	KP091843/KP091844
	CYP76AH4	Ferruginol synthase	[53]
	CYP76AK7/8	11-Hydroxyferruginol-20-oxidase	KX431219/KX431220
Salvia fruticosa	CYP76AH24	Ferruginol synthase/Ferruginol-11-hydroxylase	KP091842
Salvia miltiorrhiza	CYP76AK6	11-Hydroxyferruginol-20-oxidase	KX431218
	CYP76AH1	Ferruginol synthase	JX422213
Salvia fruticosa	CYP76AH3	Ferruginol/sugiol-11-hydroxylase	KR140168
	CYP76AK1	11-Hydroxyferruginol-20-hydroxylase	KR140169
Salvia miltiorrhiza	CYP701A	ent-Kaurene oxidase	KJ606394
Salvia pomifera	CYP71BE52	Ferruginol-2-synthase	KT157042
	CYP76AH24	Ferruginol synthase/Ferruginol-11-hydroxylase	KT157044
	CYP76AK6	11-Hydroxyferruginol-20-oxidase	KT157045
Stevia rebaudiana	CYP701A5	ent-Kaurene oxidase	AY364317
Taxus canadensis	CYP725A6	Taxoid 2α-hydroxylase	AY518383
Taxus cuspidata	CYP725A1	5α-Taxadienol-10β-hydroxylase	AF318211
Stevia rebaudiana	CYP725A2	Taxane 13α-hydroxylase	AY056019
Taxus canadensis	CYP725A3	Taxane-14β-hydroxylase	AY188177
Taxus cuspidata	CYP725A4	Taxadiene-5 α-hydroxylase	AY289209
Vitex agnus-castus	CYP725A5	Taxoid-7β-hydroxylase	AY307951
Lotus corniculatus L.	CYP76BK1	Peregrinol-16-hydroxylase	MG696754.1
Catharanthus roseusd	CYP71D353	20-Hydroxylupeol-28-oxidase	AHB62239.1
	CYP716AL1	β-Amyrin-28-hydroxylase	AEX07773.1
Bupleurum roots	CYP716Y1	β-Amyrin-16-hydroxylase	AHF45909.1
Glycyrrhizae uralesis	CYP88D6	β-Amyrin-11-oxidase	QBC36431.1
Catharanthus roseusd	CYP93E3	β-Amyrin-24-hydroxylase	BAG68930.1
Bupleurum roots	CYP72A154	β-Amyrin-30-oxidase	H1A988.1
Medicago truncatula	CYP93E2	β-Amyrin-24-hydroxylase	ABC59085.1
	CYP716A12	α, β-Amyrin-28-oxidase	ABC59076.1
	CYP72A63	β-Amyrin-30-hydroxylase	H1A981.1
Medicago truncatula	CYP72A68v2	β-Amyrin-23-hydroxylase	BAL45204.1
Panax ginseng	CYP93E2	β-Amyrin-24-hydroxylase	ABC59085.1
	CYP716A12	β-Amyrin-28-oxidase	ABC59076.1
	CYP716A52v2	β-Amyrin-28-oxidase	AFO63032.1
	CYP716A47	Dammarenediol-12-hydroxylase	AEY75212.1
	CYP716A53v2	Protopanaxadiol-6-hydroxylase	I7CT85.1
Platycodon grandiflorus	CYP716A140	β-Amyrin-28-oxidase	AOG74836.1
	CYP716A141	Dammarenediol-12-hydroxylase	AOG74838.1
	CYP716S5	Oleanolic acid-12, 13α-epoxidase	AOG74839.1
Centella asiatica	CYP716A83/86	β-Amyrin-28-oxidase	AOG74832/AOG74831
	CYP716E41	Oleanolic acid-6β-oxidase	AOG74834.1
	CYP716C11	Oleanolic acid-2α-oxidase	AOG74835.1
Veratrum californicum	CYP90B27v1	Cholesterol-22-hydroxylase	KJ869252
	CYP90G1	22-Hydroxy-26-aminocholesterol-22-oxidase	KJ869260
	CYP94N1	22-Hydroxycholesterol-26-oxidase	KJ869255
Ajuga reptans	CYP71D443	Cholesterol-22-hydroxylase	BAS30379.1
Paris polyphylla	CYP90B27	Cholesterol-22-hydroxylase	KX904822
	CYP90G4	Cholesterol-5, 6-spiroketaloxidase	QDS03628
Trigonella foenum-graecum	CYP90B50	Cholesterol-5, 6-spiroketaloxidase	QDS03633.1

), ArticleFig(id=1220655378405180200, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=

Plant	Gene	Function	Gene Bank ID
Catharanthus roseus	CYP72A224	7-Deoxyloganic acid-7-hydroxylase	AGX93062.1
	CYP71BJ1	Tabersonine/lochnericine-19-hydroxylase	ADZ48681.1
	CYP76B6	Geraniol-8-hydroxylase	AJ251269
	CYP72A1	Secologanin synthase	Q05047.1
	CYP76A26	7-Deoxyloganetic acid synthase	AHX24370.1
	CYP71D351	Tabersonine-16-hydroxylase	U5HKE8
	CYP71D12	Tabersonine-16-hydroxylase	FJ647194.1
Papaver somniferum	CYP80B1	(S)-N-Methylcoclaurine-3'-hydroxylase	AAF61400.1
	CYP719B1	Salutaridine synthase	ABR14720.1
	CYP82Y1	(S)-N-Methylcanadine-1-hydroxylase	QBG82621.1
	CYP82X1	(13S, 14R)-13-O-Acetyl-1-hydroxy-N-methylcanadine-8-hydroxylase	AFB74614.1
	CYP82N4	(S)-cis-N-Methylstylopine-14-hydroxylase	L7X3S1
	CYP82N3	Protopine-6-hydroxylase	L7X0L7
	CYP719A21	(S)-Canadine synthase	I3QBP4.1
Berberis stolonifera	CYP80A1	Berbamunine synthase	P47195.1
Camptotheca acuminate	CYP76B4	Geraniol-8-hydroxylase	AES93118
	CYP72A565	7-Deoxyloganic acid-7-oxidase/Loganin synthase/secologanin synthase	QDC27812
	CYP72A610		QDC27813
Hyoscyamusniger	CYP80F1	Littorine mutase	ABD39696.1
Coptis japonica	CYP80B2	(S)-N-Methylcoclaurine-3'-hydroxylase	BAB12433.1
	CYP719A1	Canadinesynthase (methylenedioxy bridge-forming)	BAB68769.1
	CYP80G2	(S)-Corytuberine synthase	BAF80448.1
Rauwolfia serpentina	CYP82S18	Vinorine hydroxylase	KY926696
Argemone mexicana	CYP719A13	(S)-Stylopine synthase/(S)-Nandinine synthase/(S)-Canadine synthase	B1NF19.1
Eschscholzia californica	CYP719A5	Cheilanthifoline synthase	B5UAQ8.1
	CYP719A9	Reticulineoxidase (methylenedioxy bridge-forming)	BAG75114.1

), ArticleFig(id=1220655378522620720, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, language=CN, label=Table 2, caption=

P450s involved in biosynthesis of alkaloids in medicinal plants

, figureFileSmall=null, figureFileBig=null, tableContent=

Plant	Gene	Function	Gene Bank ID
Catharanthus roseus	CYP72A224	7-Deoxyloganic acid-7-hydroxylase	AGX93062.1
	CYP71BJ1	Tabersonine/lochnericine-19-hydroxylase	ADZ48681.1
	CYP76B6	Geraniol-8-hydroxylase	AJ251269
	CYP72A1	Secologanin synthase	Q05047.1
	CYP76A26	7-Deoxyloganetic acid synthase	AHX24370.1
	CYP71D351	Tabersonine-16-hydroxylase	U5HKE8
	CYP71D12	Tabersonine-16-hydroxylase	FJ647194.1
Papaver somniferum	CYP80B1	(S)-N-Methylcoclaurine-3'-hydroxylase	AAF61400.1
	CYP719B1	Salutaridine synthase	ABR14720.1
	CYP82Y1	(S)-N-Methylcanadine-1-hydroxylase	QBG82621.1
	CYP82X1	(13S, 14R)-13-O-Acetyl-1-hydroxy-N-methylcanadine-8-hydroxylase	AFB74614.1
	CYP82N4	(S)-cis-N-Methylstylopine-14-hydroxylase	L7X3S1
	CYP82N3	Protopine-6-hydroxylase	L7X0L7
	CYP719A21	(S)-Canadine synthase	I3QBP4.1
Berberis stolonifera	CYP80A1	Berbamunine synthase	P47195.1
Camptotheca acuminate	CYP76B4	Geraniol-8-hydroxylase	AES93118
	CYP72A565	7-Deoxyloganic acid-7-oxidase/Loganin synthase/secologanin synthase	QDC27812
	CYP72A610		QDC27813
Hyoscyamusniger	CYP80F1	Littorine mutase	ABD39696.1
Coptis japonica	CYP80B2	(S)-N-Methylcoclaurine-3'-hydroxylase	BAB12433.1
	CYP719A1	Canadinesynthase (methylenedioxy bridge-forming)	BAB68769.1
	CYP80G2	(S)-Corytuberine synthase	BAF80448.1
Rauwolfia serpentina	CYP82S18	Vinorine hydroxylase	KY926696
Argemone mexicana	CYP719A13	(S)-Stylopine synthase/(S)-Nandinine synthase/(S)-Canadine synthase	B1NF19.1
Eschscholzia californica	CYP719A5	Cheilanthifoline synthase	B5UAQ8.1
	CYP719A9	Reticulineoxidase (methylenedioxy bridge-forming)	BAG75114.1

), ArticleFig(id=1220655378610701105, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=

Plant	Gene	Function	Gene Bank ID
Catharanthus roseus	CYP75A8	Flavonoid-3', 5'-hydroxylase	AJ011862
Glycyrrhiza echinata L.	CYP93C2	2-Hydroxyisoflavanone synthase	AB023636
CYP81E1	Isoflavone 2'-hydroxylase	AB001379
Erigeron breviscapus	CYP706X	Flavone-6-hydroxylase	Ebre_g017226
Scutellariabaicalensis Georgi	CYP82D1.1	Flavone-6-hydroxylase	ASW21050.1
	CYP82D2	Flavone-8-hydroxylase	ASW21052.1
Medicago truncatula	CYP73A3	Cinnamate-4-hydroxylase	DQ335792.1
Antirrhinum majus	CYP93B3	Flavone synthase II	AB028151
Perilla frutescens	CYP93B6	Flavone synthase II	AB045592
	CYP75B4	Flavonoid 3'-hydroxylase	AB045593
	CYP98A6	ρ-Coumaroyl ester 3'-hydroxylase	BBB04707.1
Ruta graveolens	CYP98A22	ρ-Coumaroyl ester 3'-hydroxylase	AEG19446.1
Eucalyptus cladocalyx	CYP71B103	Mandelonitrile synthase	AYN73069.1
	CYP706C55	Phenylacetaldoximedehydralase	AYN73068.1
Fallopia sachalinensis	CYP71AT96	Phenylacetonitrile synthase	BAU59406.1
Hypericum perforatum	CYP81AA1	1, 3, 7-Trihydroxyxanthone synthase	ANC33510.1
Croton stellatopilosus	CYP76F45	Geraniol-8-hydroxylase	AIO11760.1
Arnebia euchroma	CYP76B74	Geranylhydroquinone-3''-hydroxylase	AZU97066.1

), ArticleFig(id=1220655378698781494, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1220655370847043762, language=CN, label=Table 3, caption=

P450 involved in biosynthesis of phenylpropanoids and other compounds in medicinal plants

, figureFileSmall=null, figureFileBig=null, tableContent=

Plant	Gene	Function	Gene Bank ID
Catharanthus roseus	CYP75A8	Flavonoid-3', 5'-hydroxylase	AJ011862
Glycyrrhiza echinata L.	CYP93C2	2-Hydroxyisoflavanone synthase	AB023636
CYP81E1	Isoflavone 2'-hydroxylase	AB001379
Erigeron breviscapus	CYP706X	Flavone-6-hydroxylase	Ebre_g017226
Scutellariabaicalensis Georgi	CYP82D1.1	Flavone-6-hydroxylase	ASW21050.1
	CYP82D2	Flavone-8-hydroxylase	ASW21052.1
Medicago truncatula	CYP73A3	Cinnamate-4-hydroxylase	DQ335792.1
Antirrhinum majus	CYP93B3	Flavone synthase II	AB028151
Perilla frutescens	CYP93B6	Flavone synthase II	AB045592
	CYP75B4	Flavonoid 3'-hydroxylase	AB045593
	CYP98A6	ρ-Coumaroyl ester 3'-hydroxylase	BBB04707.1
Ruta graveolens	CYP98A22	ρ-Coumaroyl ester 3'-hydroxylase	AEG19446.1
Eucalyptus cladocalyx	CYP71B103	Mandelonitrile synthase	AYN73069.1
	CYP706C55	Phenylacetaldoximedehydralase	AYN73068.1
Fallopia sachalinensis	CYP71AT96	Phenylacetonitrile synthase	BAU59406.1
Hypericum perforatum	CYP81AA1	1, 3, 7-Trihydroxyxanthone synthase	ANC33510.1
Croton stellatopilosus	CYP76F45	Geraniol-8-hydroxylase	AIO11760.1
Arnebia euchroma	CYP76B74	Geranylhydroquinone-3''-hydroxylase	AZU97066.1

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