Article(id=1208491448681476586, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491447892947355, articleNumber=null, orderNo=null, doi=10.16438/j.0513-4870.2020-1751, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1605024000000, receivedDateStr=2020-11-11, revisedDate=1610985600000, revisedDateStr=2021-01-19, acceptedDate=null, acceptedDateStr=null, onlineDate=1766056414051, onlineDateStr=2025-12-18, pubDate=1623427200000, pubDateStr=2021-06-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1766056414051, onlineIssueDateStr=2025-12-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1766056414051, creator=13701087609, updateTime=1766056414051, updator=13701087609, issue=Issue{id=1208491447892947355, tenantId=1146029695717560320, journalId=1189982191388893191, year='2021', volume='56', issue='6', pageStart='1513', pageEnd='1748', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1766056413863, creator=13701087609, updateTime=1766137152975, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1208830092319519523, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491447892947355, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1208830092319519524, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491447892947355, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1532, endPage=1536, ext={EN=ArticleExt(id=1208491449155432992, articleId=1208491448681476586, tenantId=1146029695717560320, journalId=1189982191388893191, language=EN, title=The latest research progress of torpor occurrence mechanism, columnId=1190335348648547107, journalTitle=Acta Pharmaceutica Sinica, columnName=Reviews, runingTitle=null, highlight=null, articleAbstract=
Torpor refers to a state in which the metabolic activity in the body of the living animal is greatly reduced during the period of reduced food supply, which is manifested as a substantial decrease in body temperature, metabolic level, and exercise level. Mammals have a strict body temperature regulation system to maintain a constant body temperature. When the energy supply is insufficient for a long time, some mammals will enter a hibernation state. Torpor is very similar to the hibernation state. The research on the mechanism of torpor state is of great significance in aerospace, military medicine and other fields. This review summarizes the specific mechanisms regulating the occurrence of torpor from four aspects: adenylate cyclase activating polypeptide (adcyap) neurons, leptin, pyroglutamylated RFamide peptide (QRFP) neurons, and sympathetic nervous system, aiming to provide ideas for further research on the mechanism of torpor.
, correspAuthors=Jian-jun* ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=Copyright ©2021 Acta Pharmaceutica Sinica. All rights reserved., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Zi-yu ZHU, Jian-wei JIANG, Jian-jun* ZHANG), CN=ArticleExt(id=1208491452137583343, articleId=1208491448681476586, tenantId=1146029695717560320, journalId=1189982191388893191, language=CN, title=Torpor发生机制最新研究进展, columnId=1190335349655180086, journalTitle=药学学报, columnName=综述, runingTitle=null, highlight=null, articleAbstract=
Torpor是指在食物供应减少时期，为维持生存，动物体内代谢活性大幅降低的一种状态，表现为体温、代谢水平和运动水平大幅降低。哺乳动物拥有一套严格的体温调节系统以维持体温恒定，当能量长时间供给不足时，部分哺乳动物会进入冬眠状态，torpor与冬眠状态表现十分类似。研究torpor状态的发生机制在航空航天和军事医学等领域具有重要意义。本文主要从adcyap (adenylate cyclase activating polypeptide)神经元、瘦素、QRFP(pyroglutamylated RFamide peptide)神经元和交感神经系统等4方面就调控torpor状态发生的具体机制进行总结，旨在为torpor发生机制的进一步研究提供思路。
, correspAuthors=张建军, authorNote=null, correspAuthorsNote=
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Pyroglutamylated RFamide peptide neurons distribution<sup>[<a href="javascript:;" class="mag_content_a" onclick="piaofuRef(this,'b19')" rid="b19">19</a>]</sup>. MPA: Medial preoptic area; AVPe: Anteroventral petriventricular nucleus , figureFileSmall=EnZbPEKc2R0XWuA2X73qmQ==, figureFileBig=bLQhj8XAnuSwAHe72+h5gg==, tableContent=null), ArticleFig(id=1208491457527263407, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491448681476586, language=EN, label=null, caption=null, figureFileSmall=nyQ9suXTJC+s/PO+ibMD8w==, figureFileBig=EY8oR0Ker1TQZ7QKBDbzrQ==, tableContent=null), ArticleFig(id=1208491457632121016, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491448681476586, language=CN, label=Figure 2, caption=
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