Article(id=1208491434466980428, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491433888166474, articleNumber=null, orderNo=null, doi=10.16438/j.0513-4870.2020-1563, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1601049600000, receivedDateStr=2020-09-26, revisedDate=1604592000000, revisedDateStr=2020-11-06, acceptedDate=null, acceptedDateStr=null, onlineDate=1766056410661, onlineDateStr=2025-12-18, pubDate=1631376000000, pubDateStr=2021-09-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1766056410661, onlineIssueDateStr=2025-12-18, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1766056410661, creator=13701087609, updateTime=1766056410661, updator=13701087609, issue=Issue{id=1208491433888166474, tenantId=1146029695717560320, journalId=1189982191388893191, year='2021', volume='56', issue='9', pageStart='2325', pageEnd='2596', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1766056410524, creator=13701087609, updateTime=1766137069648, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1208829742833332989, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491433888166474, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1208829742833332990, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1208491433888166474, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=2528, endPage=2535, ext={EN=ArticleExt(id=1208491434857050703, articleId=1208491434466980428, tenantId=1146029695717560320, journalId=1189982191388893191, language=EN, title=Protective effects of the total glycosides of
Cistanche deserticola Y. C. Ma in alcoholic liver injury in mice, columnId=1190335348761793317, journalTitle=Acta Pharmaceutica Sinica, columnName=Original Articles, runingTitle=null, highlight=null, articleAbstract=
Modern pharmacological studies have shown that Cistanche deserticola (C. deserticola) has a protective effect on the liver, but its active fraction and mechanism are not clear. In order to identify the effective fraction of C. deserticola Y. C. Ma, an acute alcoholic liver injury model in mice was established with 56-proof Erguotou and different fractional extracts of C. deserticola Y. C. Ma (total glycosides, polysaccharides, and oligosaccharides) were administered. After 14 days of oral administration, liver pathology and lipid deposition were measured and the expression of nuclear factor E2-related factor (Nrf-2), kelch-like ECH-associated protein-1 (Keap-1), and plasmalemma vesicle-associated protein-1 (PV1) were measured by immunofluorescence. The levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), endotoxin (ET), diamine oxidase (DAO), and D-lactic acid (D-LA) in serum, and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT), and malondialdehyde (MDA) in liver were measured by ELISA. All animal experiments were carried out with approval of the Experimental Animal Welfare Ethics Committee of the Peking University Health Science Center. The results show that the total glycosides of C. deserticola Y. C. Ma (400 mg·kg-1) could decrease liver pathology, decrease serum endotoxin, diamine oxidase, and D-lactic acid, and reduce hepatic lipid deposition. Total glycosides also promoted Nrf-2 transfer into the nucleus and decreased the expression of Keap-1 and PV1. In summary, the total glycosides of C. deserticola Y. C. Ma had a protective effect in acute alcoholic liver injury and the mechanism may be related to the activation of the Nrf-2/Keap-1 pathway, improvement of intestinal wall integrity, and inhibition of the transport of harmful substances into the liver.
, correspAuthors=Ke-wu ZENG, Yong JIANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=Copyright ©2021 Acta Pharmaceutica Sinica. All rights reserved., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Fu-jiang WANG, Peng-fei TU, Ke-wu ZENG, Yong JIANG), CN=ArticleExt(id=1208491437876949678, articleId=1208491434466980428, tenantId=1146029695717560320, journalId=1189982191388893191, language=CN, title=荒漠肉苁蓉总苷对酒精性肝损伤小鼠的保护作用研究, columnId=1190335348896011050, journalTitle=药学学报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=
现代药理研究表明荒漠肉苁蓉具有肝保护作用，但其活性部位及作用机制并不清楚。为了明确荒漠肉苁蓉发挥肝保护作用的活性部位，本研究建立了急性酒精性肝损伤小鼠模型，并在此基础上对荒漠肉苁蓉的不同提取物部位（荒漠肉苁蓉总苷、荒漠肉苁蓉多糖和荒漠肉苁蓉寡糖）进行肝保护活性筛选。连续灌胃给药14天后，检测小鼠的肝脏病理结构及脂质沉积，并采用免疫荧光检测核因子E2相关因子（nuclear factor E2 related factors，Nrf-2）、胞质蛋白伴侣分子（kelch-like ECH-associated protein-1，Keap-1）及质膜囊泡相关蛋白1（plasmalemma vesicle-associated protein-1，PV1）的蛋白表达，采用ELISA方法检测血清中谷丙转氨酶（alanine aminotransferase，ALT）、谷草转氨酶（aspartate aminotransferase，AST）、内毒素（endotoxin，ET）、二胺氧化酶（diamine oxidase，DAO）和D-乳酸（D-lactic acid，D-LA）含量，及肝脏中超氧化物歧化酶（superoxide dismutase，SOD）、谷胱甘肽过氧化物酶（glutathione peroxidase，GSH-Px）及过氧化氢酶（catalase，CAT）活性和丙二醛（malondialdehyde，MDA）含量。动物实验操作和福利均遵循北京大学医学部实验动物伦理与动物福利委员会的规定。结果显示，与模型组相比，荒漠肉苁蓉总苷能够改善肝脏病理结构及降低肝脏中脂质沉积和血清中ET、DAO和D-LA含量。同时，荒漠肉苁蓉总苷能够促进Nrf-2入核并降低Keap-1和PV1表达。由此可见，荒漠肉苁蓉总苷在400 mg·kg-1剂量下对急性酒精性肝损伤具有保护作用，其作用机制可能与激活Nrf-2/Keap-1通路和改善肠壁完整性有关。
, correspAuthors=曾克武, 姜勇, authorNote=null, correspAuthorsNote=
, copyrightStatement=版权所有©《药学学报》编辑部2021, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=/ibOmSd4GT8vKtWOQY372w==, magXml=s1k0qj0h0yO3UIbhNNC1LA==, pdfUrl=null, pdf=KJJ8cwEsWxTWdMgfeWgYjQ==, pdfFileSize=972134, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=FacisaXu/wDtOmHbP+znuQ==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=TheZXnwIqcxnC7hD1ryRyw==, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=王富江, 屠鹏飞, 曾克武, 姜勇)}, authors=[Author(id=1208491438334128836, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1208491438468346572, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491438334128836, language=EN, stringName=Fu-jiang WANG, firstName=Fu-jiang, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1208491438589981398, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491438334128836, language=CN, stringName=王富江, firstName=富江, middleName=null, lastName=王, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=北京大学天然药物与仿生药物国家重点实验室, 北京 100191, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1208491438208299707, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, xref=null, ext=[AuthorCompanyExt(id=1208491438212494012, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China), AuthorCompanyExt(id=1208491438225076925, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=北京大学天然药物与仿生药物国家重点实验室, 北京 100191)])]), Author(id=1208491438703227617, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1208491438837445356, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491438703227617, language=EN, stringName=Peng-fei TU, firstName=Peng-fei, middleName=null, lastName=TU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1208491438959080184, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491438703227617, language=CN, stringName=屠鹏飞, firstName=鹏飞, middleName=null, lastName=屠, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=北京大学天然药物与仿生药物国家重点实验室, 北京 100191, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1208491438208299707, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, xref=null, ext=[AuthorCompanyExt(id=1208491438212494012, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China), AuthorCompanyExt(id=1208491438225076925, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=北京大学天然药物与仿生药物国家重点实验室, 北京 100191)])]), Author(id=1208491439076520705, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=ZKW@bjmu.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1208491439152018187, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491439076520705, language=EN, stringName=Ke-wu ZENG, firstName=Ke-wu, middleName=null, lastName=ZENG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
*, address=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1208491439227515667, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491439076520705, language=CN, stringName=曾克武, firstName=克武, middleName=null, lastName=曾, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
*, address=北京大学天然药物与仿生药物国家重点实验室, 北京 100191, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1208491438208299707, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, xref=null, ext=[AuthorCompanyExt(id=1208491438212494012, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China), AuthorCompanyExt(id=1208491438225076925, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=北京大学天然药物与仿生药物国家重点实验室, 北京 100191)])]), Author(id=1208491439357539102, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=yongjiang@bjmu.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1208491439454008103, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491439357539102, language=EN, stringName=Yong JIANG, firstName=Yong, middleName=null, lastName=JIANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
*, address=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1208491439571448626, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, authorId=1208491439357539102, language=CN, stringName=姜勇, firstName=勇, middleName=null, lastName=姜, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
*, address=北京大学天然药物与仿生药物国家重点实验室, 北京 100191, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1208491438208299707, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, xref=null, ext=[AuthorCompanyExt(id=1208491438212494012, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China), AuthorCompanyExt(id=1208491438225076925, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=北京大学天然药物与仿生药物国家重点实验室, 北京 100191)])])], keywords=[Keyword(id=1208491439730832195, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, orderNo=1, keyword=
Cistanche deserticola Y. C. Ma), Keyword(id=1208491439852467022, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, orderNo=2, keyword=alcoholic liver disease), Keyword(id=1208491439927964505, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, orderNo=3, keyword=total glycosides of
C. deserticola Y. C. Ma), Keyword(id=1208491440020239204, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, orderNo=4, keyword=liver protection), Keyword(id=1208491440129291119, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, orderNo=5, keyword=Nrf-2/Keap-1 pathway), Keyword(id=1208491440217371510, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, orderNo=1, keyword=肉苁蓉), Keyword(id=1208491440305451904, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, orderNo=2, keyword=酒精性肝损伤), Keyword(id=1208491440393532300, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, orderNo=3, keyword=荒漠肉苁蓉总苷), Keyword(id=1208491440473224084, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, orderNo=4, keyword=肝保护), Keyword(id=1208491440557110177, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, orderNo=5, keyword=Nrf-2/Keap-1通路)], refs=[Reference(id=1208491444449423526, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2018, volume=53, issue=null, pageStart=236, pageEnd=243, url=http://www.yxxb.com.cn:8081/aps/CN/abstract/abstract17100.shtml, language=null, rfNumber=[1], rfOrder=0, authorNames=Zhang YW, Li YJ, Hu BF, journalName=Acta Pharm Sin (药学学报), refType=null, unstructuredReference=
Zhang YW ,
Li YJ ,
Hu BF et al . Evaluation on three short-term animal models of alcoholic liver disease[J].
Acta Pharm Sin (药学学报),
2018,
53: 236-243., articleTitle=Evaluation on three short-term animal models of alcoholic liver disease, refAbstract=null), Reference(id=1208491444613001394, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/j.ejim.2007.06.033, pmid=null, pmcid=null, year=2008, volume=19, issue=null, pageStart=561, pageEnd=567, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=Vonghia L, Leggio L, Ferrulli A, journalName=Eur J Intern Med, refType=null, unstructuredReference=
Vonghia L ,
Leggio L ,
Ferrulli A et al . Acute alcohol intoxication[J].
Eur J Intern Med,
2008,
19: 561-567., articleTitle=Acute alcohol intoxication, refAbstract=null), Reference(id=1208491444747219135, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2018, volume=34, issue=null, pageStart=1128, pageEnd=1132, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=Hou J, Lu Y, Zhang DK, journalName=J Clin Hepatol, refType=null, unstructuredReference=
Hou J ,
Lu Y ,
Zhang DK . Association between intestinal dysbacteriosis and liver diseases[J].
J Clin Hepatol,
2018,
34: 1128-1132., articleTitle=Association between intestinal dysbacteriosis and liver diseases, refAbstract=null), Reference(id=1208491444852076746, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/j.biopha.2018.01.114, pmid=null, pmcid=null, year=2018, volume=99, issue=null, pageStart=671, pageEnd=680, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=Liu Y, Wang H, Yang M, journalName=Biomed Pharmacother, refType=null, unstructuredReference=
Liu Y ,
Wang H ,
Yang M et al .
Cistanche deserticola polysaccharides protects PC12 cells against OGD/RP-induced injury[J].
Biomed Pharmacother,
2018,
99: 671-680., articleTitle=
Cistanche deserticola polysaccharides protects PC12 cells against OGD/RP-induced injury, refAbstract=null), Reference(id=1208491444931768533, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1002/jcp.26882, pmid=null, pmcid=null, year=2018, volume=233, issue=null, pageStart=9674, pageEnd=9684, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=Song DZ, Cao Z, Liu ZB, journalName=J Cell Physiol, refType=null, unstructuredReference=
Song DZ ,
Cao Z ,
Liu ZB et al .
Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption
via inhibiting RANKL signaling and reactive oxygen species production[J].
J Cell Physiol,
2018,
233: 9674-9684., articleTitle=
Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption
via inhibiting RANKL signaling and reactive oxygen species production, refAbstract=null), Reference(id=1208491445032431839, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1371/journal.pone.0191356, pmid=null, pmcid=null, year=2018, volume=13, issue=null, pageStart=e0191356, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=Zhang AL, Yang XM, Li QX, journalName=PLoS One, refType=null, unstructuredReference=
Zhang AL ,
Yang XM ,
Li QX et al . Immunostimulatory activity of water-extractable polysaccharides from
Cistanche deserticola as a plant adjuvant
in vitro and
in vivo[J].
PLoS One,
2018,
13: e0191356., articleTitle=Immunostimulatory activity of water-extractable polysaccharides from
Cistanche deserticola as a plant adjuvant
in vitro and
in vivo, refAbstract=null), Reference(id=1208491445120512231, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/j.ijbiomac.2018.11.132, pmid=null, pmcid=null, year=2019, volume=124, issue=null, pageStart=360, pageEnd=367, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=Zhang H, Xiang Z, Duan X, journalName=Int J Biol Macromol, refType=null, unstructuredReference=
Zhang H ,
Xiang Z ,
Duan X et al . Antitumor and anti-inflammatory effects of oligosaccharides from
Cistanche deserticola extract on spinal cord injury[J].
Int J Biol Macromol,
2019,
124: 360-367., articleTitle=Antitumor and anti-inflammatory effects of oligosaccharides from
Cistanche deserticola extract on spinal cord injury, refAbstract=null), Reference(id=1208491445284090103, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.5246/jcps.2019.08.051, pmid=null, pmcid=null, year=2019, volume=28, issue=null, pageStart=537, pageEnd=546, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=Li RY, Zhao MB, Tu PF, journalName=J Chin Pharm Sci, refType=null, unstructuredReference=
Li RY ,
Zhao MB ,
Tu PF et al . Simultaneous determination of five phenylethanoid glycosides in Cistanches Herba using quantitative analysis of multi-components by single marker[J].
J Chin Pharm Sci,
2019,
28: 537-546., articleTitle=Simultaneous determination of five phenylethanoid glycosides in Cistanches Herba using quantitative analysis of multi-components by single marker, refAbstract=null), Reference(id=1208491445372170493, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2017, volume=33, issue=null, pageStart=2154, pageEnd=2157, url=http://en.cnki.com.cn/Article_en/CJFDTOTAL-GLYZ201721018.htm, language=null, rfNumber=[9], rfOrder=8, authorNames=Li SQ, Lu HJ, Wang P, journalName=Chin J Clin Pharmacol (中国临床药理学杂志), refType=null, unstructuredReference=
Li SQ ,
Lu HJ ,
Wang P et al . Study on the time of cell apoptosis in alcoholic liver injury in mice[J].
Chin J Clin Pharmacol (中国临床药理学杂志),
2017,
33: 2154-2157., articleTitle=Study on the time of cell apoptosis in alcoholic liver injury in mice, refAbstract=null), Reference(id=1208491445523165455, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2019, volume=21, issue=null, pageStart=1641, pageEnd=1646, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=Shi ZY, Wu Y, Zhu YM, journalName=Mod Chin Med (中国现代中药), refType=null, unstructuredReference=
Shi ZY ,
Wu Y ,
Zhu YM et al . Quantitative determination of betaine, mannitol, fructose, glucose and sucrose in Cistanches Herba by HPLC-ELSD[J].
Mod Chin Med (中国现代中药),
2019,
21: 1641-1646., articleTitle=Quantitative determination of betaine, mannitol, fructose, glucose and sucrose in Cistanches Herba by HPLC-ELSD, refAbstract=null), Reference(id=1208491446735319324, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2015, volume=17, issue=null, pageStart=307, pageEnd=310, url=http://en.cnki.com.cn/Article_en/CJFDTOTAL-YJXX201504005.htm, language=null, rfNumber=[11], rfOrder=10, authorNames=Gao YJ, Jiang Y, Dai F, journalName=Mod Chin Med (中国现代中药), refType=null, unstructuredReference=
Gao YJ ,
Jiang Y ,
Dai F et al . Study on laxative constituents in
Cistanche deserticola Y. C. Ma[J].
Mod Chin Med (中国现代中药),
2015,
17: 307-310., articleTitle=Study on laxative constituents in
Cistanche deserticola Y. C. Ma, refAbstract=null), Reference(id=1208491446898897195, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2016, volume=30, issue=null, pageStart=504, pageEnd=510, url=http://www.zhangqiaokeyan.com/academic-journal-cn_chinese-journal-pharmacology-toxicology_thesis/0201242162601.html, language=null, rfNumber=[12], rfOrder=11, authorNames=You SP, Zhao J, Ma L, journalName=Chin J Pharmacol Toxicol (中国药理学与毒理学杂志), refType=null, unstructuredReference=
You SP ,
Zhao J ,
Ma L et al . Effect and mechanism of
Cistanche phenylethanoid glycosides on rats with immunological liver fibrosis[J].
Chin J Pharmacol Toxicol (中国药理学与毒理学杂志),
2016,
30: 504-510., articleTitle=Effect and mechanism of
Cistanche phenylethanoid glycosides on rats with immunological liver fibrosis, refAbstract=null), Reference(id=1208491447020532026, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2009, volume=14, issue=null, pageStart=1225, pageEnd=1228, url=http://en.cnki.com.cn/Article_en/CJFDTOTAL-YLZL200911009.htm, language=null, rfNumber=[13], rfOrder=12, authorNames=Luo HY, Liu Y, Xi GZ, journalName=Chin J Clin Pharmacol Ther (中国临床药理学与治疗学), refType=null, unstructuredReference=
Luo HY ,
Liu Y ,
Xi GZ et al . Protective effect of Cistanchis glycosides on ethanol-induced liver damage in mice[J].
Chin J Clin Pharmacol Ther (中国临床药理学与治疗学),
2009,
14: 1225-1228., articleTitle=Protective effect of Cistanchis glycosides on ethanol-induced liver damage in mice, refAbstract=null), Reference(id=1208491447146361159, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/j.taap.2012.05.010, pmid=null, pmcid=null, year=2012, volume=262, issue=null, pageStart=321, pageEnd=329, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=Wu KC, Liu J, Klaassen CD, journalName=Toxicol Appl Pharmacol, refType=null, unstructuredReference=
Wu KC ,
Liu J ,
Klaassen CD . Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation[J].
Toxicol Appl Pharmacol,
2012,
262: 321-329., articleTitle=Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation, refAbstract=null), Reference(id=1208491447255413076, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/j.tox.2014.02.008, pmid=null, pmcid=null, year=2014, volume=324, issue=null, pageStart=35, pageEnd=42, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=Qu Q, Liu J, Zhou HH, journalName=Toxicology, refType=null, unstructuredReference=
Qu Q ,
Liu J ,
Zhou HH et al . Nrf2 protects against furosemide-induced hepatotoxicity[J].
Toxicology,
2014,
324: 35-42., articleTitle=Nrf2 protects against furosemide-induced hepatotoxicity, refAbstract=null), Reference(id=1208491447347687780, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=null, pmid=null, pmcid=null, year=2016, volume=51, issue=null, pageStart=843, pageEnd=852, url=http://www.yxxb.com.cn:8081/aps/CN/abstract/abstract16039.shtml, language=null, rfNumber=[16], rfOrder=15, authorNames=Zhang L, Zu XP, Xie HS, journalName=Acta Pharm Sin (药学学报), refType=null, unstructuredReference=
Zhang L ,
Zu XP ,
Xie HS et al . Research progress in mechanism of intestinal microorganisms in human diseases[J].
Acta Pharm Sin (药学学报),
2016,
51: 843-852., articleTitle=Research progress in mechanism of intestinal microorganisms in human diseases, refAbstract=null), Reference(id=1208491447523848560, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, doi=10.1016/S0168-8278(00)80242-1, pmid=null, pmcid=null, year=2000, volume=32, issue=null, pageStart=742, pageEnd=747, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=Parlesak A, Schäfer C, Schütz T, journalName=J Hepatol, refType=null, unstructuredReference=
Parlesak A ,
Schäfer C ,
Schütz T et al . Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease[J].
J Hepatol,
2000,
32: 742-747., articleTitle=Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease, refAbstract=null)], funds=[Fund(id=1208491444155822221, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, awardId=2017YFC1702402, language=CN, fundingSource=国家重点研发计划(2017YFC1702402), fundOrder=null, country=null), Fund(id=1208491444269068442, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, awardId=81773932, language=CN, fundingSource=国家自然科学基金资助项目(81773932), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1208491438208299707, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, xref=null, ext=[AuthorCompanyExt(id=1208491438212494012, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China), AuthorCompanyExt(id=1208491438225076925, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, companyId=1208491438208299707, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=北京大学天然药物与仿生药物国家重点实验室, 北京 100191)])], figs=[ArticleFig(id=1208491440754242483, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=XJKxhAdfQD4IRIwJyG1lgw==, figureFileBig=FacisaXu/wDtOmHbP+znuQ==, tableContent=null), ArticleFig(id=1208491440829739968, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 1, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on liver index in alcoholic liver injury mice. <i>n</i> = 8, ± <i>s.</i> <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD. NOR: Normal group; MOD: Model group; BIF: Bifendate group; TGs: Total glycosides group; PSs: Polysaccharides group: OSs: Oligosaccharides group , figureFileSmall=XJKxhAdfQD4IRIwJyG1lgw==, figureFileBig=FacisaXu/wDtOmHbP+znuQ==, tableContent=null), ArticleFig(id=1208491441052038104, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=c8plMADmu8RTJATr0AS3SQ==, figureFileBig=kQ37x023+zBIW8UF8kAn8g==, tableContent=null), ArticleFig(id=1208491442276774882, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 2, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on histopathological changes of liver in alcoholic liver injury mice. <i>n</i> = 5. Scale bar = 100 μm , figureFileSmall=c8plMADmu8RTJATr0AS3SQ==, figureFileBig=kQ37x023+zBIW8UF8kAn8g==, tableContent=null), ArticleFig(id=1208491442406798321, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=YfnVShhnysVuAfEsdWRnuw==, figureFileBig=i1toDP8LPIHQ2osBjpfkbQ==, tableContent=null), ArticleFig(id=1208491442494878712, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 3, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on lipid deposition of liver in alcoholic liver injury mice. A: Oil red O staining; B: Quantitative analysis of lipid deposition in different groups. <i>n</i> = 5, ± <i>s.</i> <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD. Scale bar = 100 μm , figureFileSmall=YfnVShhnysVuAfEsdWRnuw==, figureFileBig=i1toDP8LPIHQ2osBjpfkbQ==, tableContent=null), ArticleFig(id=1208491442616512514, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=VQx77O69fo8QSKGsKavDKQ==, figureFileBig=yp8qSbZ5wfiKvW44A0pMng==, tableContent=null), ArticleFig(id=1208491442725564425, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 4, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in alcoholic liver injury mice. <i>n</i> = 5, ± <i>s</i>. <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD , figureFileSmall=VQx77O69fo8QSKGsKavDKQ==, figureFileBig=yp8qSbZ5wfiKvW44A0pMng==, tableContent=null), ArticleFig(id=1208491442796867602, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=Na86jwK48zMPtz2a/+D8lw==, figureFileBig=rRmYWKi3GS/p8NPB2My7HQ==, tableContent=null), ArticleFig(id=1208491442880753690, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 5, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on apoptosis in alcoholic liver injury mice. A: TUNEL staining of liver sections; B: Quantitative analysis of apoptosis in different groups. <i>n</i> = 5, ± <i>s.</i> <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD. Scale bar = 100 μm , figureFileSmall=Na86jwK48zMPtz2a/+D8lw==, figureFileBig=rRmYWKi3GS/p8NPB2My7HQ==, tableContent=null), ArticleFig(id=1208491442973028384, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=NxIDFnwrVkoj1zVrwUiVqw==, figureFileBig=uDYZ9Bw/P5Jbwng9DwsQkA==, tableContent=null), ArticleFig(id=1208491443052720172, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 6, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on histopathological changes of small intestine in alcoholic liver injury mice. <i>n</i> = 5. Scale bar = 100 μm , figureFileSmall=NxIDFnwrVkoj1zVrwUiVqw==, figureFileBig=uDYZ9Bw/P5Jbwng9DwsQkA==, tableContent=null), ArticleFig(id=1208491443144994871, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=FQWxnQmVChwErNMTqBplLw==, figureFileBig=BMEqNOApTaYbcbWDS8qoFg==, tableContent=null), ArticleFig(id=1208491443254046785, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 7, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on the expression of plasmalemma vesicle-associated protein-1 (PV1) in alcoholic liver injury mice. A: Immunofluorescence staining of small intestine sections; B: Bar graph showed a quantification of the expression of PV1. <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD; <sup>$</sup><i>P</i> < 0.05 <i>vs</i> BIF. <i>n</i> = 3, ± <i>s.</i> Scale bar = 100 μm , figureFileSmall=FQWxnQmVChwErNMTqBplLw==, figureFileBig=BMEqNOApTaYbcbWDS8qoFg==, tableContent=null), ArticleFig(id=1208491443367293003, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=Ygwo45xTUZj34JuHQVAiDQ==, figureFileBig=u1Wcb5mSyeI+rdf2GaNGcw==, tableContent=null), ArticleFig(id=1208491443480539224, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 8, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on contents of endotoxin (ET), diamine oxidase (DAO), and <i>D</i>-lactic acid (<i>D</i>-LA) in alcoholic liver injury mice. <i>n</i> = 5, ± <i>s</i>. <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD , figureFileSmall=Ygwo45xTUZj34JuHQVAiDQ==, figureFileBig=u1Wcb5mSyeI+rdf2GaNGcw==, tableContent=null), ArticleFig(id=1208491443602174047, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=wKOJFLphMKgbyoBK3QQu5A==, figureFileBig=cJruZ6/eppM0W34MjQIX6w==, tableContent=null), ArticleFig(id=1208491443715420263, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 9, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on nuclear factor E2 related factors (Nrf-2)/kelch-like ECH-associated protein-1 (Keap-1) pathway in alcoholic liver injury mice. A: Immunofluorescence staining and quantitative statistics of Nrf-2, scale bar = 50 μm; B: Immunofluorescence staining and quantitative statistics of Keap-1, scale bar = 100 μm. <i>n</i> = 5, ± <i>s</i>. <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD , figureFileSmall=wKOJFLphMKgbyoBK3QQu5A==, figureFileBig=cJruZ6/eppM0W34MjQIX6w==, tableContent=null), ArticleFig(id=1208491443824472180, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=EN, label=null, caption=null, figureFileSmall=mYOboScGrGp91LVLrDE9Aw==, figureFileBig=bpolRc57OGnI3znmX5wUhQ==, tableContent=null), ArticleFig(id=1208491443967078527, tenantId=1146029695717560320, journalId=1189982191388893191, articleId=1208491434466980428, language=CN, label=Figure 10, caption=
Effects of extracts of <i>C. deserticola</i> Y. C. Ma on oxidative stress of liver in alcoholic liver injury mice. <i>n</i> = 5, ± <i>s</i>. <sup>*</sup><i>P</i> < 0.05 <i>vs</i> NOR; <sup>#</sup><i>P</i> < 0.05 <i>vs</i> MOD. CAT: Catalase; GSH-Px: Glutathione peroxidase; MDA: Malondialdehyde; SOD: Superoxide dismutase , figureFileSmall=mYOboScGrGp91LVLrDE9Aw==, figureFileBig=bpolRc57OGnI3znmX5wUhQ==, tableContent=null)], attaches=null, journal=Journal(id=1189982048455397383, delFlag=0, nameCn=药学学报, nameEn=Acta Pharmaceutica Sinica, nameHistory1=null, nameHistory2=null, issn=0513-4870, eissn=null, cn=11-2163/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=BTxjudbJDVO4PqdBR6On6Q==, journalPrice=null, startedYear=null, abbrevIsoEn=null, journalRemark=null, publicationField=null, createdTime=1761643429151, updatedTime=1761735768113, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=A, firstLetterEn=A, subjectCode=Life Sciences, subjectName=Life Sciences, subjectCodeEn=Life Sciences, subjectNameEn=null, picCn=BTxjudbJDVO4PqdBR6On6Q==, picEn=c4l1ckL55nWbhl1KrFdWIA==, jcr=null, cjcr=null, exts=[JournalExt(id=1190369346338783397, language=CN, name=药学学报, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1761735768160, updatedTime=1761735768160, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.yxxb.com.cn/journalx_yxxb/authorLogOn.action, submissionEditorUrl=https://www.yxxb.com.cn/journalx_yxxb/editorLogOn.action, submissionReviewUrl=https://www.yxxb.com.cn/journalx_yxxb/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1190369346376532134, language=EN, name=Acta Pharmaceutica Sinica, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1761735768169, updatedTime=1761735768169, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.yxxb.com.cn/journalx_yxxb/authorLogOn.action, submissionEditorUrl=https://www.yxxb.com.cn/journalx_yxxb/editorLogOn.action, submissionReviewUrl=https://www.yxxb.com.cn/journalx_yxxb/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1189982191388893191, websiteList=[Website(id=1189982271588340489, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1189982191388893191, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/yxxb/CN, language=CN, createTime=1761643482348, createBy=18614031015, updateTime=1761643498101, updateBy=18614031015, name=药学学报-中文, tplId=1146099689490845704, title=药学学报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1189982873114448678, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=articleTextType, value=kx, createTime=1761643625763, updateTime=1761643625763, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873093477155, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=banner, value=null, createTime=1761643625758, updateTime=1761643625758, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873135420201, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=grayFlag, value=0, createTime=1761643625768, updateTime=1761643625768, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873085088546, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=logo, value=https://castjournals.cast.org.cn/joweb/yxxb/CN/file/pic?fileId=w+t2v8bJnX5lh3+hRRJcDA==, createTime=1761643625756, updateTime=1761643625756, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873152197419, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=minRunFlag, value=0, createTime=1761643625772, updateTime=1761643625772, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873110254373, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/yxxb/CN/file/pic, createTime=1761643625762, updateTime=1761643625762, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873143808810, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=silenceFlag, value=0, createTime=1761643625770, updateTime=1761643625770, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873101865764, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1761643625760, updateTime=1761643625760, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873122837287, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=themeColor, value=null, createTime=1761643625765, updateTime=1761643625765, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982873127031592, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271588340489, code=themeStyle, value=null, createTime=1761643625766, updateTime=1761643625766, creator=18614031015, updator=18614031015)]), Website(id=1189982271655449355, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1189982191388893191, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/yxxb/EN, language=EN, createTime=1761643482364, createBy=18614031015, updateTime=1761643514085, updateBy=18614031015, name=药学学报-英文, tplId=1146101810881728533, title=Acta Pharmaceutica Sinica, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1189982903015633534, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=articleTextType, value=kx, createTime=1761643632892, updateTime=1761643632892, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982902990467707, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=banner, value=null, createTime=1761643632886, updateTime=1761643632886, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903036605057, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=grayFlag, value=0, createTime=1761643632897, updateTime=1761643632897, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982902982079098, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=logo, value=https://castjournals.cast.org.cn/joweb/yxxb/EN/file/pic?fileId=w+t2v8bJnX5lh3+hRRJcDA==, createTime=1761643632884, updateTime=1761643632884, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903053382275, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=minRunFlag, value=0, createTime=1761643632901, updateTime=1761643632901, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903007244925, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/yxxb/EN/file/pic, createTime=1761643632890, updateTime=1761643632890, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903044993666, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=silenceFlag, value=0, createTime=1761643632899, updateTime=1761643632899, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982902998856316, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1761643632888, updateTime=1761643632888, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903019827839, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=themeColor, value=null, createTime=1761643632893, updateTime=1761643632893, creator=18614031015, updator=18614031015), WebsiteProps(id=1189982903028216448, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1189982271655449355, code=themeStyle, value=null, createTime=1761643632895, updateTime=1761643632895, creator=18614031015, updator=18614031015)])], journalTitle=药学学报, weixinUrl=null, journalUrl=https://www.yxxb.com.cn/aps, iacademicId=null, status=1, seqNo=null, journalTitleEn=Acta Pharmaceutica Sinica, journalPhotoCn=BTxjudbJDVO4PqdBR6On6Q==, journalPhotoEn=c4l1ckL55nWbhl1KrFdWIA==, journalFirstLetter=A, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false), detailUrlCn=https://castjournals.cast.org.cn/joweb/yxxb/CN/10.16438/j.0513-4870.2020-1563, detailUrlEn=https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2020-1563, pdfUrlCn=https://castjournals.cast.org.cn/joweb/yxxb/CN/PDF/10.16438/j.0513-4870.2020-1563, pdfUrlEn=https://castjournals.cast.org.cn/joweb/yxxb/EN/PDF/10.16438/j.0513-4870.2020-1563, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, reference=null)
全屏
文章导航
PDF下载
192
118
关闭全屏
北京市海淀区学院南路86号
010-62199257
qkjq@cast.org.cn
