Article(id=1198624474955346551, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1198624466902287155, articleNumber=null, orderNo=null, doi=10.16438/j.0513-4870.2022-1089, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1664812800000, receivedDateStr=2022-10-04, revisedDate=1675699200000, revisedDateStr=2023-02-07, acceptedDate=null, acceptedDateStr=null, onlineDate=1763703944195, onlineDateStr=2025-11-21, pubDate=1681228800000, pubDateStr=2023-04-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1763703944195, onlineIssueDateStr=2025-11-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1763703944195, creator=13701087609, updateTime=1763703944195, updator=13701087609, issue=Issue{id=1198624466902287155, tenantId=1146029695717560320, journalId=1189982191388893191, year='2023', volume='58', issue='4', pageStart='1', pageEnd='1092', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1763703942275, creator=13701087609, updateTime=1763704125380, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1198625234971619912, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1198624466902287155, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1198625234971619913, tenantId=1146029695717560320, journalId=1189982191388893191, issueId=1198624466902287155, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=852, endPage=855, ext={EN=ArticleExt(id=1198624475370582686, articleId=1198624474955346551, tenantId=1146029695717560320, journalId=1189982191388893191, language=EN, title=Advance on anti-tumor theranostics and biosafety of bismuth-based nanomedicine, columnId=null, journalTitle=Acta Pharmaceutica Sinica, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Nanomedicine is one of the most promising fields in biomedicine. Inorganic nanomaterials stand out among many nanomaterials due to their excellent physicochemical properties, stable chemical properties and high biocompatibility. As an inorganic nanomaterial, bismuth-based nanomaterials have the advantages of adjustable band gap, low toxicity, easy functionalization, large X-ray attenuation coefficient, high photothermal conversion efficiency and long cycle half-life, so they have good promising application in cancer diagnosis and treatment. This review summarizes the recent research progress of bismuth-based nanomaterials in tumor diagnosis, treatment and biosafety, which provides a theoretical basis for the design and exploitation of a new generation of bismuth-based nanomedicine systems.
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纳米生物医学是生物医药领域中最具有应用前景的方向之一, 无机纳米材料由于其优良的物理、化学特性、稳定的化学性质以及高生物相容性, 在众多的纳米材料中脱颖而出。作为一种低成本的无机纳米材料, 铋基纳米材料由于具有带隙可调、低毒性、易于功能化、较大X射线衰减系数、较高光热转换效率和长循环半衰期等优势, 在癌症诊断和治疗方面具有种种潜在的用途和广阔的应用前景。本文综述了铋基纳米材料在肿瘤诊断、治疗和生物安全性方面的最新研究进展, 为新一代铋基纳米药物系统的设计和开发提供理论依据和开发思路。
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