Article(id=1320388825893941289, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388792901554957, articleNumber=null, orderNo=null, doi=10.11876/mimt202506008, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792734827730, onlineDateStr=2026-10-23, pubDate=1765296000000, pubDateStr=2025-12-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792734827730, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792734827730, creator=13701087609, updateTime=1792734827730, updator=13701087609, issue=Issue{id=1320388792901554957, tenantId=1146029695717560320, journalId=1319373289681944729, year='2025', volume='31', issue='6', pageStart='1', pageEnd='96', issueExtLink='null', onlineDate='null', pubDate='1765296000000', pubDateStr='2025-12-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792734819865, creator='13701087609', updateTime=1792746371372, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320437243483902178, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388792901554957, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320437243483902179, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388792901554957, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=48, endPage=52, ext={EN=ArticleExt(id=1320388826044936234, articleId=1320388825893941289, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=Diagnostic value of high-resolution CT in pulmonary adenocarcinoma presenting as pure ground-glass nodules, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the association between CT features and histopathology of lung adenocarcinoma presenting as pure ground-glass nodules under high-resolution CT examination conditions.
Methods A retrospective analysis was conducted on the CT manifestations of lung adenocarcinoma with pure ground-glass nodules confirmed by pathology in our hospital from October 2021 to December 2024. The main objective factors to be observed are the size and density of ground-glass nodules, as well as the CT manifestations such as vacuole sign, bronchial changes, vascular changes, presence or absence of spicules, lobulation and nodule - lung interface. Compare the differences in CT features among different histopathological subtypes: pre-invasive group [including atypical adenomatous hyperplasia (AAH) and adenocarcinoma in situ (AIS)] and invasive group [including minimally invasive adenocarcinoma (MIA) and invasive adenocarcinoma cancer (IAC)].
Results This study enrolled a total of 419 patients with pulmonary nodules. The pathological subtypes included 21 cases (5.0%) of AAH, 133 cases (31.7%) of AIS, 123 cases (29.4%) of MIA, and 142 cases (33.9%) of IAC. The invasive group showed significantly greater lesion size, long-to-short diameter ratio, mean CT attenuation, CT enhancement, and standard deviation of CT values than the pre-invasive group (P<0.05). The incidences of vascular abnormality, air-space change, and tumor–lung interface abnormality were also higher in the invasive group than in the pre-invasive group (P<0.05).
Conclusion A diagnostic framework for the precise preoperative grading of pure ground-glass nodule pulmonary adenocarcinoma can be constructed from high-resolution CT features, providing important basis for assessment of invasion degree and treatment decision-making.
, authors=Yan Li, Yunjian Li
*, authorsList=Yan Li, Yunjian Li, authorCompany=null, correspAuthors=Yunjian Li, authorNote=null, correspAuthorsNote=null, copyrightStatement=
All copyrights in 2025 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320388826309177387, articleId=1320388825893941289, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=高分辨率CT在表现为纯磨玻璃结节肺腺癌中的诊断价值, columnId=1320381058969883180, journalTitle=现代仪器与医疗, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 分析在高分辨率CT（high-resolution CT，HRCT）检查条件下表现为纯磨玻璃结节（pure ground-glass nodule，pGGN）的肺腺癌的CT特征与病理组织学之间的联系。
方法 采用回顾性研究方法，选取我院2021年10月至2024年12月收治的经病理证实的pGGN肺腺癌患者作为研究对象。根据病理组织学结果将病变分为浸润前病变[包括不典型腺瘤样增生（atypical adenomatous hyperplasia，AAH）和原位腺癌（adenocarcinoma in situ，AIS）]和浸润性病变[包括微浸润性腺癌（minimally invasive adenocarcinoma，MIA）和浸润性腺癌（invasive adenocarcinoma cancer，IAC）]两类，比较两类病变在CT特征和血管、气腔及瘤肺交界面特征方面的差异。
结果 本研究共纳入419例肺结节患者，病理类型包括AAH 21例（5.0%）、AIS 133例（31.7%）、MIA123例（29.4%）和IAC 142例（33.9%）。浸润性病变组的病变大小、长短径比值、平均CT值、CT增加值及CT值标准差均显著高于浸润前病变组，差异均有统计学意义（P<0.05）。浸润性病变组的血管改变、气腔改变和瘤肺交界面异常发生率高于浸润前病变组，差异均有统计学意义（P<0.05）。
结论 HRCT的定量与形态学特征可构建用于pGGN肺腺癌术前精准分级的诊断框架，为浸润程度评估及治疗决策提供重要依据。
, authors=李艳, 李运健
*, authorsList=李艳, 李运健, authorCompany=null, correspAuthors=李运健, authorNote=
李艳，女，硕士研究生，副主任医师，研究方向：心胸乳腺方向
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李运健，男，硕士研究生，副主任医师，研究方向：心胸方向
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2025年版权归本刊主办单位所有未经本刊书面许可, 不得转载、摘编本刊所有文章内容。, copyrightOwner=中国科学器材公司, extLink=null, articleAbsUrl=null, sourceXml=Vjlkrm6ZKid9RXYFCB+vWA==, magXml=uorZR8zpSEVG+VJOvybRWQ==, pdfUrl=null, pdf=v9DXDef8k411xxxEQPtOyQ==, pdfFileSize=1532488, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=uctcQsG84psVSUQOuOxihg==, mapNumber=null, fund=null)}, authors=[Author(id=1320388826577612848, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388825893941289, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320388826644721714, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388825893941289, authorId=1320388826577612848, language=EN, stringName=Yan Li, firstName=Yan, middleName=null, lastName=Li, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Imaging Department, the Third People's Hospital of Yancheng City, Yancheng 224008, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320388826720219187, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388825893941289, authorId=1320388826577612848, language=CN, stringName=李艳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=江苏省盐城市第三人民医院影像科，盐城 224008, bio={"content":"
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