Article(id=1320381145674527418, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381108315870143, articleNumber=null, orderNo=null, doi=10.11876/mimt202603016, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1770566400000, receivedDateStr=2026-02-09, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792732996624, onlineDateStr=2026-10-23, pubDate=1781020800000, pubDateStr=2026-06-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792732996624, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792732996624, creator=13701087609, updateTime=1792732996624, updator=13701087609, issue=Issue{id=1320381108315870143, tenantId=1146029695717560320, journalId=1319373289681944729, year='2026', volume='32', issue='3', pageStart='1', pageEnd='132', issueExtLink='null', onlineDate='null', pubDate='1781020800000', pubDateStr='2026-06-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792732987716, creator='13701087609', updateTime=1792746098645, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320436099600728986, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381108315870143, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320436099600728987, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381108315870143, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=110, endPage=114, ext={EN=ArticleExt(id=1320381145850688187, articleId=1320381145674527418, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=Application value of endoscopic ultrasound-guided fine-needle aspiration/biopsy in upper gastrointestinal and extramural lesions, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the clinical diagnostic value and safety of endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) in upper gastrointestinal and extramural lesions.
Methods A retrospective analysis was performed on 50 patients who underwent EUS-FNA/B from January 2024 to December 2025. The final comprehensive diagnosis was based on surgical pathology when available, or on follow-up imaging and treatment response in nonsurgical cases. Diagnostic agreement, sensitivity, specificity, predictive values, accuracy, AUC and complications were analyzed.
Results The final diagnosis included 18 benign and 32 malignant lesions. EUS-FNA/B identified 31 malignant and 19 benign lesions, with 30 true positives, 17 true negatives, 2 false negatives and 1 false positive. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 93.75%, 94.44%, 96.77%, 89.47% and 94.00%, respectively. The AUC was 0.94. No serious complications occurred.
Conclusion EUS-FNA/B has high diagnostic accuracy and favorable safety for upper gastrointestinal and extramural lesions, and can provide reliable evidence for clinical decision-making.
, authors=Lixin Ren, Baoping Di, Shengyong Zhou, Yihua Dou, authorsList=Lixin Ren, Baoping Di, Shengyong Zhou, Yihua Dou, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=
All copyrights in 2026 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320381146081374908, articleId=1320381145674527418, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=超声内镜引导下细针穿刺抽吸或活检对上消化道及壁外占位性病变的诊断价值, columnId=1320381058969883180, journalTitle=现代仪器与医疗, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 探讨超声内镜引导下细针穿刺抽吸或活检（endoscopic ultrasound-guided fine-needle aspiration/biopsy，EUS-FNA/B）在上消化道及壁外占位性病变诊断中的临床应用价值及安全性。
方法 采用回顾性分析方法，选取2024年1月至2025年12月在我院消化内镜中心接受EUS-FNA/B检查的上消化道及壁外占位性病变患者50例。以手术切除标本病理结果、影像学复查结果和临床治疗反应的综合诊断结果作为诊断参考标准，比较EUS-FNA/B诊断结果与最终综合诊断结果的一致性，计算其诊断敏感度、特异度、阳性预测值、阴性预测值及总体诊断准确率，并绘制受试者工作特征（receiver operating characteristic，ROC）曲线，计算曲线下面积（area under curve，AUC），评价诊断效能。同时观察检查相关并发症发生情况。
结果 最终综合诊断结果显示，良性病变18例，恶性病变32例。EUS-FNA/B诊断恶性病变31例、良性病变19例；与综合诊断结果比较，真阳性30例、真阴性17例、假阴性2例、假阳性1例。EUS-FNA/B诊断的敏感度为93.75%，特异度为94.44%，阳性预测值为96.77%，阴性预测值为89.47%，总体诊断准确率为94.00%。ROC曲线分析显示AUC为0.94。检查过程中及术后未出现严重并发症，仅个别患者出现轻度咽部不适或短暂腹部胀痛，经对症处理后缓解。
结论 EUS-FNA/B在上消化道及壁外占位性病变诊断中具有较高的准确性及良好的安全性，可为病变性质判断及临床治疗决策提供可靠依据，具有一定的临床应用价值。
, authors=任丽新, 邸宝平, 周生勇, 窦义花, authorsList=任丽新, 邸宝平, 周生勇, 窦义花, authorCompany=null, correspAuthors=null, authorNote=
任丽新，女，本科，副主任医师，研究方向：消化内科及消化内镜
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2026年版权归本刊主办单位所有未经本刊书面许可, 不得转载、摘编本刊所有文章内容。, copyrightOwner=中国科学器材公司, extLink=null, articleAbsUrl=null, sourceXml=ItPCQQfmd8Usoo8phGqBeA==, magXml=fj58DGCqjOeAIW1jJ1sxwQ==, pdfUrl=null, pdf=ezUOLe18obvYgYrohgpcLA==, pdfFileSize=1656720, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=VsdHHFhIcGkU0ls7qKzVvA==, mapNumber=null, fund=null)}, authors=[Author(id=1320381146400142017, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381145674527418, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320381146484028099, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381145674527418, authorId=1320381146400142017, language=EN, stringName=Lixin Ren, firstName=Lixin, middleName=null, lastName=Ren, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Jiayuguan First People's Hospital, Jiayuguan 735100, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320381146559525572, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381145674527418, authorId=1320381146400142017, language=CN, stringName=任丽新, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=嘉峪关市第一人民医院，嘉峪关 735100, bio={"content":"
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