Article(id=1320381177572213166, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381076653060187, articleNumber=null, orderNo=null, doi=10.11876/mimt202602014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792733004229, onlineDateStr=2026-10-23, pubDate=1775750400000, pubDateStr=2026-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792733004229, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792733004229, creator=13701087609, updateTime=1792733004229, updator=13701087609, issue=Issue{id=1320381076653060187, tenantId=1146029695717560320, journalId=1319373289681944729, year='2026', volume='32', issue='2', pageStart='1', pageEnd='120', issueExtLink='null', onlineDate='null', pubDate='1775750400000', pubDateStr='2026-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792732980168, creator='13701087609', updateTime=1792746330832, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320437073467789517, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381076653060187, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320437073467789518, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381076653060187, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=85, endPage=90, ext={EN=ArticleExt(id=1320381177781928367, articleId=1320381177572213166, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=The diagnostic value of contrast-enhanced ultrasound guided biopsy in the differential diagnosis of benign and malignant liver lesions, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) guided biopsy in the differential diagnosis of benign and malignant liver lesions.
Methods A total of 160 patients with suspected liver cancer admitted to Qinzhou First People's Hospital from December 2022 to December 2023 were retrospectively selected, and all of them received conventional ultrasound-guided and CEUS-guided puncture biopsy after admission, and the detection, diagnostic efficacy and contrast-enhanced ultrasound indexes of benign and malignant lesions were analyzed with the results of pathological examination as the gold standard.
Results Among the 160 patients with suspected liver cancer, 95 were malignant and 65 were benign confirmed by surgery and pathology. CEUS-guided biopsy detected 84 cases of malignant and 60 cases of benign, with a positive rate of 88.42% (84/95). The sensitivity, specificity and accuracy of CEUS-guided biopsy were 88.42%, 92.31% and 90.00%, respectively, which were significantly higher than those of conventional ultrasound-guided biopsy (69.47%, 75.38% and 71.86%, respectively), while the missed diagnosis rate and misdiagnosis rate of CEUS-guided biopsy were 11.58% and 7.69%, respectively, which were significantly lower than those of conventional ultrasound-guided biopsy (30.53% and 24.62%, respectively), with statistically significant differences (all P<0.05). The regional blood flow (rBF) and perfusion index of malignant lesions in arterial phase were higher than those of benign lesions (P<0.05), and the rBF in delayed phase was lower than that of benign lesions (P<0.05). The initial peak time, peak time, rise time and transit time of contrast agent were shorter than those of benign lesions (P<0.05).
Conclusion For the differential diagnosis of benign and malignant liver lesions, CEUS-guided biopsy has higher sensitivity, specificity and accuracy than conventional ultrasound. It can observe the blood perfusion characteristics of liver lesions and effectively distinguish between benign and malignant liver diseases.
, authors=Juyi Jiang, Yongrong Liang, Qibin Su, Jiapeng Zhou, Peisheng Wu
*, authorsList=Juyi Jiang, Yongrong Liang, Qibin Su, Jiapeng Zhou, Peisheng Wu, authorCompany=null, correspAuthors=Peisheng Wu, authorNote=null, correspAuthorsNote=null, copyrightStatement=
All copyrights in 2026 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320381178096501168, articleId=1320381177572213166, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=超声造影引导下穿刺活检对肝脏良恶性病变鉴别的诊断价值, columnId=1320381058969883180, journalTitle=现代仪器与医疗, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 探究超声造影（contrast-enhanced ultrasound，CEUS）引导下的穿刺活检对肝脏良恶性病变鉴别的诊断价值。
方法 回顾性选取2022年12月至2023年12月期间钦州市第一人民医院收治的160例疑似肝癌患者，入院后均接受常规超声引导下及CEUS引导下的穿刺活检，以病理学检查结果为金标准，分析良恶性病变检出情况、诊断效能和超声造影指标。
结果 160例疑似肝癌患者中经手术病理确诊恶性95例、良性65例，CEUS引导下穿刺活检检出恶性84例、良性60例，阳性率为88.42%（84/95）；CEUS引导下穿刺活检的灵敏度、特异度、准确度分别为88.42%、92.31%、90.00%，显著高于常规超声引导下穿刺活检的69.47%、75.38%、71.86%，同时CEUS引导下穿刺活检漏诊率、误诊率分别为11.58%、7.69%，显著低于常规超声引导下穿刺活检的30.53%、24.62%，差异均有统计学意义（P<0.05）。恶性病变动脉期局部血流量（regional blood flow，rBF）和灌注指数高于良性病变，延迟期rBF低于良性病变，造影剂始峰时间、达峰时间、上升时间、通过时间短于良性病变，差异均有统计学意义（P<0.05）。
结论 肝脏良恶性病变鉴别选择CEUS引导下的穿刺活检，灵敏度、特异度、准确度均高于常规超声，可观察肝脏病变的血流灌注特征，能够有效鉴别肝脏良恶性病变。
, authors=蒋居毅, 梁泳荣, 苏奇斌, 周佳鹏, 吴培生
*, authorsList=蒋居毅, 梁泳荣, 苏奇斌, 周佳鹏, 吴培生, authorCompany=null, correspAuthors=吴培生, authorNote=
蒋居毅，男，硕士研究生，主治医师，研究方向：肝胆胰外科临床工作
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吴培生，男，本科，副主任医师，研究方向：肝胆胰外科临床工作
, copyrightStatement=
2026年版权归本刊主办单位所有未经本刊书面许可, 不得转载、摘编本刊所有文章内容。, copyrightOwner=中国科学器材公司, extLink=null, articleAbsUrl=null, sourceXml=wNfZM7KPqsQjVKkPSUmB0A==, magXml=uoC32MPd7QvHPyeXcwSi+w==, pdfUrl=null, pdf=3umZNRQ2jzuA+ZpA9nT6gA==, pdfFileSize=2153194, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=B/b4fwqM8Q9xId24gLrnlg==, mapNumber=null, fund=null)}, authors=[Author(id=1320381178369130933, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381177572213166, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320381180021686711, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381177572213166, authorId=1320381178369130933, language=EN, stringName=Juyi Jiang, firstName=Juyi, middleName=null, lastName=Jiang, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Hepatobiliary and Pancreatic Surgery, the First People's Hospital of Qinzhou, Qinzhou 535009, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320381180105572792, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381177572213166, authorId=1320381178369130933, language=CN, stringName=蒋居毅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=钦州市第一人民医院肝胆胰外科，钦州 535009, bio={"content":"
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