Article(id=1320381087327568535, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, articleNumber=null, orderNo=null, doi=10.11876/mimt202601016, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792732982712, onlineDateStr=2026-10-23, pubDate=1770652800000, pubDateStr=2026-02-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792732982712, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792732982712, creator=13701087609, updateTime=1792732982712, updator=13701087609, issue=Issue{id=1320381045866873144, tenantId=1146029695717560320, journalId=1319373289681944729, year='2026', volume='32', issue='1', pageStart='1', pageEnd='106', issueExtLink='null', onlineDate='null', pubDate='1770652800000', pubDateStr='2026-02-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792732972828, creator='13701087609', updateTime=1792746352003, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320437162382840024, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320437162382840025, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=102, endPage=106, ext={EN=ArticleExt(id=1320381087520506520, articleId=1320381087327568535, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=Clinical efficacy of optimal pulse technology combined with fluorometholone eye drops in the treatment of dry eye associated with Sjögren's syndrome, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the clinical efficacy of optimal pulse technology (OPT) combined with 0.1% fluorometholone eye drops in the treatment of dry eye related to Sjögren's syndrome.
Methods One hundred patients with Sjögren's syndrome-related dry eye treated in our hospital from March 2021 to March 2025 were selected as the study subjects and randomly divided into a control group and an experimental group, with 50 patients in each group. The control group received 0.3% sodium hyaluronate eye drops, 0.1% fluorometholone eye drops combined with standardized meibomian gland massage and warm compress. The experimental group received the same treatment as the control group, with the addition of OPT treatment. The tear film break-up time (BUT), tear meniscus height (TMH), results of the Schirmer I test (SIt), ocular surface disease index (OSDI) score, corneal fluorescein staining (FL) score, emotional status [self-rating anxiety scale (SAS) score and self-rating depression scale (SDS) score], and treatment efficacy were compared between the two groups.
Results After treatment, the experimental group exhibited significantly higher values in BUT, TMH, and SIt compared to the control group, with statistically significant differences (P<0.05). The OSDI and FL scores of the experimental group were significantly lower than those of the control group after treatment, showing statistically significant differences (P<0.05). Furthermore, the SAS and SDS scores of the experimental group were significantly lower than those of the control group after treatment, with statistically significant differences (P<0.05). The clinical efficacy of the experimental group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05).
Conclusion The combination of optimal pulse technology and fluorometholone eye drops in the treatment of dry eye related to Sjögren's syndrome can effectively improve the clinical symptoms of patients, reduce their negative emotions, and has a good therapeutic effect, which has clinical promotion value.
, authors=Rongrong Yang, Hui Su, Mengting Pan, authorsList=Rongrong Yang, Hui Su, Mengting Pan, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=
All copyrights in 2026 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320381087822496409, articleId=1320381087327568535, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=优化强脉冲光技术联合氟米龙滴眼液治疗干燥综合征相关干眼的临床疗效, columnId=1320381058969883180, journalTitle=现代仪器与医疗, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 探讨优化强脉冲光技术（optimal pulse technology，OPT）联合0.1%氟米龙滴眼液治疗干燥综合征相关干眼的临床疗效。
方法 选取2021年3月至2025年3月我院收治的100例干燥综合征相关干眼患者作为研究对象，随机分为对照组与实验组，各50例。对照组给予0.3%玻璃酸钠滴眼液、0.1%氟米龙滴眼液联合规范睑板腺按摩及热敷；实验组在对照组治疗基础上，联合OPT治疗。比较两组泪膜破裂时间（break-up time，BUT）、双眼泪河高度（tear meniscus height，TMH）、泪液分泌试验结果（Schirmer I test，SIt）、眼表疾病指数量表（ocular surface disease index，OSDI）评分、角膜荧光素染色（corneal fluorescein staining，FL）评分、情绪状态[焦虑自评量表（self-rating anxiety scale，SAS）评分、抑郁自评量表（self-rating depression scale，SDS）评分]、治疗效果。
结果 治疗后实验组BUT、TMH、SIt高于对照组，差异有统计学意义（P<0.05）。治疗后实验组OSDI、FL评分低于对照组，差异有统计学意义（P<0.05）。治疗后实验组SAS、SDS评分低于对照组，差异有统计学意义（P<0.05）。实验组治疗效果好于对照组，差异有统计学意义（P<0.05）。
结论 优化强脉冲光技术联合氟米龙滴眼液治疗干燥综合征相关干眼，可有效改善患者临床症状，降低患者负面情绪，治疗效果良好，有临床推广价值。
, authors=杨荣荣, 苏慧, 潘梦婷, authorsList=杨荣荣, 苏慧, 潘梦婷, authorCompany=null, correspAuthors=null, authorNote=
杨荣荣，女，本科，副主任医师，研究方向：眼表角膜病及干眼
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