Article(id=1320381065655603827, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, articleNumber=null, orderNo=null, doi=10.11876/mimt202601009, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792732977546, onlineDateStr=2026-10-23, pubDate=1770652800000, pubDateStr=2026-02-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792732977546, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792732977546, creator=13701087609, updateTime=1792732977546, updator=13701087609, issue=Issue{id=1320381045866873144, tenantId=1146029695717560320, journalId=1319373289681944729, year='2026', volume='32', issue='1', pageStart='1', pageEnd='106', issueExtLink='null', onlineDate='null', pubDate='1770652800000', pubDateStr='2026-02-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792732972828, creator='13701087609', updateTime=1792746352003, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320437162382840024, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320437162382840025, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320381045866873144, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=60, endPage=66, ext={EN=ArticleExt(id=1320381065840153204, articleId=1320381065655603827, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=Dosimetric analysis of dynamic and static IMRT in flattening filter free mode for left-sided early-stage breast cancer conserving surgery, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective To compare the dosimetric differences between dynamic intensity-modulated radiotherapy (dIMRT) and static intensity-modulated radiation therapy (sIMRT) with varying minimum segment area (MSA) parameters, using 6 MV flattening filter-free (FFF) photon beams for left-sided early-stage breast cancer patients after breast-conserving surgery.
Methods A retrospective study was conducted using clinical imaging and treatment data from twelve female patients with left-sided early-stage breast cancer, who were treated at the Third People's Hospital of Bengbu from March 2024 to March 2025. Each patient received dIMRT and sIMRT (MSA values of 0.3, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, 8.0, and 10.0 cm2 were applied) plans in FFF mode using treatment planning system of United Imaging. The prescription dose was 50 Gy, delivered at 2 Gy per time, 5 times per week. Plan comparisons included the dose distribution in the target volume, dose to organs at risk (OARs), skin dose (skin 0~2, skin 2~5, skin 5~8), plan efficiency [monitor units (MUs), delivery time], and gamma passing rates (1 mm/1% criteria).
Results dIMRT demonstrated slightly superior target coverage (V95, Dmean, HI) and significantly improved V107 and Dmax compared to sIMRT (P<0.05). The Dmean of heart was significantly lower in dIMRT (P<0.05). The Dmean of skin doses were reduced in dIMRT (P>0.05). Although dIMRT required higher MUs, it reduced delivery time by 25% (P<0.05). γ passing rates under 1 mm/1% criteria were marginally lower for dIMRT (MSA≤5.0 cm2, P<0.05).
Conclusion For early-stage left-sided breast cancer patients receiving IMRT after breast-conserving surgery under the FFF mode on the United Imaging platform, dIMRT demonstrates superiority over sIMRT in terms of target dose distribution, dose sparing of OARs, and delivery efficiency. It is therefore recommended that dIMRT be preferentially considered for treatment planning under similar equipment and clinical conditions.
, authors=Yaming Fan, Shuang Liu, Feng Nian, Qi Zhang, Xinyu Li, authorsList=Yaming Fan, Shuang Liu, Feng Nian, Qi Zhang, Xinyu Li, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=
All copyrights in 2026 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320381067656286837, articleId=1320381065655603827, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=非均整模式下左侧早期乳腺癌保乳术后动态与静态调强放疗技术的剂量学对比研究, columnId=1320381058969883180, journalTitle=现代仪器与医疗, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 比较6 MV光子束非均整模式（flattening filter free，FFF）下左侧早期乳腺癌保乳术后动态调强（dynamic intensity modulated radiotherapy，dIMRT）与不同最小子野面积（the minimum segment area，MSA）参数下静态调强（static intensity modulated radiotherapy，sIMRT）放疗技术的剂量学差异。
方法 回顾性收集2024年3月至2025年3月在蚌埠市第三人民医院接受放射治疗的12例左侧早期乳腺癌女性患者的临床影像与治疗资料，应用联影放射治疗计划系统（uTPS）采用FFF模式为每例患者设计dIMRT和sIMRT计划，sIMRT计划的MSA分别为0.3、1.0、2.0、3.0、4.0、5.0、6.0、8.0和10.0 cm2，每例患者得到10个计划，处方剂量为50 Gy，常规分割照射2 Gy/次，5次/周。比较不同计划的靶区剂量分布、危及器官（organs at risk，OARs）剂量受量以及计划执行效率和γ通过率。
结果 dIMRT的95%处方剂量的体积（V95）、平均剂量（Dmean）、均匀性指数（HI）均略优于sIMRT，107%处方剂量的体积（V107）、最大剂量（Dmax）具有明显优势，dIMRT心脏的Dmean明显优于sIMRT，差异均具有统计学意义（P<0.05）；dIMRT skin 0~2、skin 2~5、skin 5~8的Dmean优于sIMRT，但是差异无统计学意义（P>0.05）；dIMRT的机器跳数（monitor units，MU）明显比sIMRT高，但是治疗时间节省了约25%，差异具有统计学意义（P<0.05）；在1 mm/1%评判标准下，dIMRT的γ通过率略低于sIMRT，且当MSA≤5.0 cm2时，差异具有统计学意义（P<0.05）。
结论 基于联影平台FFF模式下的左侧早期乳腺癌保乳术后调强放疗中，dIMRT在靶区剂量分布、OARs剂量受量以及计划执行效率等方面优于sIMRT，建议在类似设备与临床条件下倾向于选择dIMRT进行计划设计。
, authors=范亚明, 刘爽, 年峰, 张琦, 李新宇, authorsList=范亚明, 刘爽, 年峰, 张琦, 李新宇, authorCompany=null, correspAuthors=null, authorNote=
范亚明，男，硕士研究生，工程师，研究方向：医用放射线设备
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2026年版权归本刊主办单位所有未经本刊书面许可, 不得转载、摘编本刊所有文章内容。, copyrightOwner=中国科学器材公司, extLink=null, articleAbsUrl=null, sourceXml=3H96tSQ7oiUV7Bwp0N9sAg==, magXml=UQBXj/6q+iKGutlXNgvobw==, pdfUrl=null, pdf=Oc9SL77msmwCtXu7/3HPYw==, pdfFileSize=2074835, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=oemDHdVzmz7Ge4ndfGBdlw==, mapNumber=null, fund=null)}, authors=[Author(id=1320381067945693818, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381065655603827, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320381068029579900, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381065655603827, authorId=1320381067945693818, language=EN, stringName=Yaming Fan, firstName=Yaming, middleName=null, lastName=Fan, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Department of Radiotherapy, the Third People's Hospital of Bengbu, Bengbu 233000, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320381068117660285, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320381065655603827, authorId=1320381067945693818, language=CN, stringName=范亚明, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=蚌埠市第三人民医院放射治疗科，蚌埠 233000, bio={"content":"
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