Article(id=1320388988398063764, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388933154878311, articleNumber=null, orderNo=null, doi=10.11876/mimt202504006, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792734866474, onlineDateStr=2026-10-23, pubDate=1754755200000, pubDateStr=2025-08-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792734866474, onlineIssueDateStr=2026-10-23, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792734866474, creator=13701087609, updateTime=1792734866474, updator=13701087609, issue=Issue{id=1320388933154878311, tenantId=1146029695717560320, journalId=1319373289681944729, year='2025', volume='31', issue='4', pageStart='2', pageEnd='132', issueExtLink='null', onlineDate='null', pubDate='1754755200000', pubDateStr='2025-08-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792734853304, creator='13701087609', updateTime=1792746408152, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1320437397758791917, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388933154878311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1320437397758791918, tenantId=1146029695717560320, journalId=1319373289681944729, issueId=1320388933154878311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=58, endPage=66, ext={EN=ArticleExt(id=1320388988813299862, articleId=1320388988398063764, tenantId=1146029695717560320, journalId=1319373289681944729, language=EN, title=Polarization control and applications in structured illumination microscopy, columnId=null, journalTitle=Modern Instruments & Medical Treatment, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Fluorescence polarization analysis requires rotating the excitation beam's polarization direction, while conventional structured illumination microscopy (SIM) relies on three illumination orientations to achieve super-resolution. Polarized structured illumination microscopy (Polar-SIM), as an integrated approach combining these two techniques, enables high-precision investigation of the spatial orientation and structure of various subcellular organelles. This study theoretically investigates the relationship between the contrast of interferometric fringes and polarization modulation, compares the advantages and disadvantages of employing a pizza waveplate, circular polarization, and a variable liquid crystal phase retarder for polarization modulation, and further simulates the accuracy of polarization analysis under different modulation conditions. Finally, our experimental results demonstrate Polar-SIM's unique capability for super-resolution directional analysis of molecular dipoles, highlighting its broad potential for addressing diverse biological questions in future research.

, authors=Wenyi Wang¹, Peng Xi^{1, 2}, Meiqi Li³, Liang Qiao^{1, *}, authorsList=Wenyi Wang, Peng Xi, Meiqi Li, Liang Qiao, authorCompany=null, correspAuthors=Liang Qiao, authorNote=null, correspAuthorsNote=null, copyrightStatement=All copyrights in 2025 belong to the sponsor of the journal.Not content published by the journal may be reproduced or abridged without authorization., copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1320388989417279641, articleId=1320388988398063764, tenantId=1146029695717560320, journalId=1319373289681944729, language=CN, title=结构光照明显微成像系统中的偏振控制及成像应用, columnId=1320388935667266410, journalTitle=现代仪器与医疗, columnName=技术进展, runingTitle=null, highlight=null, articleAbstract=

由于荧光偏振方向求解需要旋转激发光束偏振方向，而传统结构光照明显微镜需要3个方向的结构光照明来实现超分辨，因此，偏振结构光照明显微成像技术（polarized structured illumination microscopy，Polar-SIM）作为两种技术的有机结合能够在更高精度上去探究细胞内各种亚细胞器的精确空间取向与结构。本文通过理论公式探究了干涉条纹对比度与偏振调制的关系，对比了使用Pizza波片、圆偏振与可变液晶相位延迟器进行偏振调制的优缺点，同时通过仿真模拟了在不同的偏振调制情况下偏振解析结果的准确性。最后，通过多种生物实验结果证明了Polar-SIM具有独特的偶极子超分辨方向解析能力，在解决相关生物问题方面具有广阔的应用前景。

, authors=王文熠¹, 席鹏^{1, 2}, 李美琪³, 乔良^{1, *}, authorsList=王文熠, 席鹏, 李美琪, 乔良, authorCompany=null, correspAuthors=乔良, authorNote=, correspAuthorsNote=, copyrightStatement=2025年版权归本刊主办单位所有未经本刊书面许可, 不得转载、摘编本刊所有文章内容。, copyrightOwner=中国科学器材公司, extLink=null, articleAbsUrl=null, sourceXml=Mcq7iVpASjHJ8dxbWk5XIA==, magXml=Zhr9yQvTQmUFXk3ydTzfnw==, pdfUrl=null, pdf=SpRwfQ2cT+onc8edSHKEIQ==, pdfFileSize=3829283, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=vlFCBy0P71vnmLfYS3p5yQ==, mapNumber=null, fund=null)}, authors=[Author(id=1320388991472488612, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320388991560568998, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991472488612, language=EN, stringName=Wenyi Wang, firstName=Wenyi, middleName=null, lastName=Wang, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Airy Technologies Co., Ltd., Beijing 100086, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320388991627677863, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991472488612, language=CN, stringName=王文熠, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.北京艾锐精仪科技有限公司，北京　100086, bio={"content":"

王文熠，男，本科，研究方向：超分辨显微成像

"}, bioImg=null, bioContent=

王文熠，男，本科，研究方向：超分辨显微成像

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1320388989610217626, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=1., ext=[AuthorCompanyExt(id=1320388989622800539, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Airy Technologies Co., Ltd., Beijing 100086, China), AuthorCompanyExt(id=1320388989631189148, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.北京艾锐精仪科技有限公司，北京　100086)])]), Author(id=1320388991703175337, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320388991799644332, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991703175337, language=EN, stringName=Peng Xi, firstName=Peng, middleName=null, lastName=Xi, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=^1.Airy Technologies Co., Ltd., Beijing 100086, China
^2.College of Future Technology, Peking University, Beijing 100871, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320388991891919021, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991703175337, language=CN, stringName=席鹏, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=^1.北京艾锐精仪科技有限公司，北京　100086
^2.北京大学未来技术学院，北京　100871, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1320388989610217626, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=1., ext=[AuthorCompanyExt(id=1320388989622800539, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Airy Technologies Co., Ltd., Beijing 100086, China), AuthorCompanyExt(id=1320388989631189148, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.北京艾锐精仪科技有限公司，北京　100086)]), AuthorCompany(id=1320388991283744925, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=2., ext=[AuthorCompanyExt(id=1320388991292133534, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991283744925, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.College of Future Technology, Peking University, Beijing 100871, China), AuthorCompanyExt(id=1320388991304716447, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991283744925, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.北京大学未来技术学院，北京　100871)])]), Author(id=1320388991959027887, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1320388992042913969, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991959027887, language=EN, stringName=Meiqi Li, firstName=Meiqi, middleName=null, lastName=Li, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=³, address=^3.School of Life Sciences, Peking University, Beijing 100871, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320388992118411442, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388991959027887, language=CN, stringName=李美琪, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=³, address=^3.北京大学生命科学学院，北京　100871, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1320388991376019616, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=3., ext=[AuthorCompanyExt(id=1320388991384408225, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991376019616, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.School of Life Sciences, Peking University, Beijing 100871, China), AuthorCompanyExt(id=1320388991392796834, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991376019616, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.北京大学生命科学学院，北京　100871)])]), Author(id=1320388992202297524, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1320388992290377910, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388992202297524, language=EN, stringName=Liang Qiao, firstName=Liang, middleName=null, lastName=Qiao, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, *}, address=^1.Airy Technologies Co., Ltd., Beijing 100086, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1320388992361681079, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, authorId=1320388992202297524, language=CN, stringName=乔良, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, *}, address=^1.北京艾锐精仪科技有限公司，北京　100086, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1320388989610217626, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=1., ext=[AuthorCompanyExt(id=1320388989622800539, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Airy Technologies Co., Ltd., Beijing 100086, China), AuthorCompanyExt(id=1320388989631189148, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.北京艾锐精仪科技有限公司，北京　100086)])])], keywords=[Keyword(id=1320388992474927288, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=EN, orderNo=1, keyword=Structured illumination microscopy), Keyword(id=1320388992554619065, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=EN, orderNo=2, keyword=Fluorescence polarization microscopy), Keyword(id=1320388992621727930, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=EN, orderNo=3, keyword=Dipole orientation analysis), Keyword(id=1320388992705614011, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=EN, orderNo=4, keyword=Super-resolution fluorescence imaging), Keyword(id=1320388992793694396, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=CN, orderNo=1, keyword=结构光照明显微镜), Keyword(id=1320388992877580477, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=CN, orderNo=2, keyword=荧光偏振显微镜), Keyword(id=1320388992953077950, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=CN, orderNo=3, keyword=偶极子取向解析), Keyword(id=1320388993041158335, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, language=CN, orderNo=4, keyword=荧光超分辨成像)], refs=[Reference(id=1320388993334759618, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=Zunino A, Garrè G, Perego E, et al. Structured detection for simultaneous super-resolution and optical sectioning in laser scanning microscopy[J]. Nature Photonics, 2025, 19(8): 888-897., articleTitle=null, refAbstract=null), Reference(id=1320388993397674179, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang L, Chen Y, Guo J, et al. Phasor-FSTM: a new paradigm for multicolor super-resolution imaging of living cells based on fluorescence modulation and lifetime multiplexing[J]. Light: Science & Applications, 2025, 14: 32., articleTitle=null, refAbstract=null), Reference(id=1320388993477365956, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=Scipioni L, Rossetta A, Tedeschi G, et al. Phasor S-FLIM: a new paradigm for fast and robust spectral fluorescence lifetime imaging[J]. Nature Methods, 2021, 18(5): 542-550., articleTitle=null, refAbstract=null), Reference(id=1320388993540280517, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhanghao K, Chen L, Yang X S, et al. Super-resolution dipole orientation mapping via polarization demodulation[J]. Light: Science & Applications, 2016, 5: e16166., articleTitle=null, refAbstract=null), Reference(id=1320388993619972294, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=杨子仪, 李世晗, 刘芷如, 等. 荧光偏振成像技术及其生物学应用[J]. 激光与光电子学进展, 2024, 61(18): 1-15., articleTitle=null, refAbstract=null), Reference(id=1320388993691275463, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=Hall M D, Yasgar A, Peryea T, et al. Fluorescence polarization assays in high-throughput screening and drug discovery: a review[J]. Methods and Applications in Fluorescence, 2016, 4(2): 022001., articleTitle=null, refAbstract=null), Reference(id=1320388993749995720, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=Jameson D M, Croney J C. Fluorescence polarization: past, present and future[J]. Combinatorial Chemistry & High Throughput Screening, 2003, 6(3): 167-176., articleTitle=null, refAbstract=null), Reference(id=1320388993829687497, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=Masters B R. Book review: principles of fluorescence spectroscopy, third edition[J]. Journal of Biomedical Optics, 2008, 13(2): 029901., articleTitle=null, refAbstract=null), Reference(id=1320388993905184970, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=Betzig E, Patterson G H, Sougrat R, et al. Imaging intracellular fluorescent proteins at nanometer resolution[J]. Science, 2006, 313(5793): 1642-1645., articleTitle=null, refAbstract=null), Reference(id=1320388993968099531, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=Gustafsson M G L. Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy[J]. Journal of Microscopy, 2000, 198(2): 82-87., articleTitle=null, refAbstract=null), Reference(id=1320388994035208396, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=Liu Y, Lu Y, Yang X, et al. Amplified stimulated emission in upconversion nanoparticles for super-resolution nanoscopy[J]. Nature, 2017, 543(7644): 229-233., articleTitle=null, refAbstract=null), Reference(id=1320388994102317261, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=York A G, Parekh S H, Nogare D D, et al. Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy[J]. Nature Methods, 2012, 9(7): 749-754., articleTitle=null, refAbstract=null), Reference(id=1320388995754873038, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=Rego E H, Shao L. Practical structured illumination microscopy[M]//Verveer P J. Advanced fluorescence microscopy: methods and protocols. New York: Springer, 2015: 175-192., articleTitle=null, refAbstract=null), Reference(id=1320388995826176207, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhanghao K, Chen X, Liu W, et al. Super-resolution imaging of fluorescent dipoles via polarized structured illumination microscopy[J]. Nature Communications, 2019, 10(1): 4694., articleTitle=null, refAbstract=null), Reference(id=1320388995901673680, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=Wang H, Wang W, Xu X, et al. High-spatiotemporal-resolution structured illumination microscopy: principles, instrumentation, and applications[J]. Photonics Insights, 2025, 4(1): R01., articleTitle=null, refAbstract=null), Reference(id=1320388996069445841, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=Huang X, Fan J, Li L, et al. Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy[J]. Nature Biotechnology, 2018, 36: 451-459., articleTitle=null, refAbstract=null), Reference(id=1320388996136554706, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=Li Y, Cao R, Ren W, et al. High-speed autopolarization synchronization modulation three-dimensional structured illumination microscopy[J]. Advanced Photonics Nexus, 2024, 3(1): 016001., articleTitle=null, refAbstract=null), Reference(id=1320388996220440787, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=赵天宇, 周兴, 但旦, 等. 结构光照明显微中的偏振控制[J]. 物理学报, 2017, 66(14): 288-299., articleTitle=null, refAbstract=null), Reference(id=1320388996300132564, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=Duarte S, Viedma-Poyatos Á, Navarro-Carrasco E, et al. Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division[J]. Nature Communications, 2019, 10: 4200., articleTitle=null, refAbstract=null), Reference(id=1320388996363047125, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=Gatti P, Schiavon C, Cicero J, et al. Mitochondria- and ER-associated actin are required for mitochondrial fusion[J]. Nature Communications, 2025, 16: 451., articleTitle=null, refAbstract=null), Reference(id=1320388996442738902, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=Cao R, Li Y, Chen X, et al. Open-3DSIM: an open-source three-dimensional structured illumination microscopy reconstruction platform[J]. Nature Methods, 2023, 20: 1183-1186., articleTitle=null, refAbstract=null), Reference(id=1320388996509847767, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=Xu J, Wang G A, Gao L, et al. Enabling programmable dynamic DNA chemistry using small-molecule DNA binders[J]. Nature Communications, 2023, 14: 4248., articleTitle=null, refAbstract=null), Reference(id=1320388996568568024, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhong S, Qiao L, Ge X, et al. Three-dimensional dipole orientation mapping with high temporal-spatial resolution using polarization modulation[J]. PhotoniX, 2024, 5: 12., articleTitle=null, refAbstract=null), Reference(id=1320388996631482585, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=Liu Q, Liu Y, Zhao J, et al. Impact of manufacturing processes on glycerolipid and polar lipid composition and ultrastructure in infant formula[J]. Food Chemistry, 2024, 444: 138623., articleTitle=null, refAbstract=null), Reference(id=1320388996698591450, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=Liu Y, Liu Y, Liu Q, et al. Comparison of phospholipid composition and microstructure of milk fat globules contained in human milk and infant formulae[J]. Food Chemistry, 2023, 415: 135762., articleTitle=null, refAbstract=null), Reference(id=1320388996774088923, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=Blanchard A, Combs J D, Brockman J M, et al. Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope[J]. Nature Communications, 2021, 12: 4693., articleTitle=null, refAbstract=null), Reference(id=1320388996841197788, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhanghao K, Liu W, Li M, et al. High-dimensional super-resolution imaging reveals heterogeneity and dynamics of subcellular lipid membranes[J]. Nature Communications, 2020, 11: 5890., articleTitle=null, refAbstract=null), Reference(id=1320388996912500957, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=Zhanghao K, Li M, Chen X, et al. Fast segmentation and multiplexing imaging of organelles in live cells[J]. Nature Communications, 2025, 16: 2769., articleTitle=null, refAbstract=null)], funds=[Fund(id=1320388993158598848, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, awardId=62025501; 92150301; 62335008; 62405010, language=CN, fundingSource=国家自然科学基金(62025501; 92150301; 62335008; 62405010), fundOrder=null, country=null), Fund(id=1320388993229902017, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, awardId=2022YFC3401100, language=CN, fundingSource=国家重点研发计划(2022YFC3401100), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1320388989610217626, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=1., ext=[AuthorCompanyExt(id=1320388989622800539, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.Airy Technologies Co., Ltd., Beijing 100086, China), AuthorCompanyExt(id=1320388989631189148, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388989610217626, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.北京艾锐精仪科技有限公司，北京　100086)]), AuthorCompany(id=1320388991283744925, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=2., ext=[AuthorCompanyExt(id=1320388991292133534, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991283744925, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.College of Future Technology, Peking University, Beijing 100871, China), AuthorCompanyExt(id=1320388991304716447, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991283744925, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.北京大学未来技术学院，北京　100871)]), AuthorCompany(id=1320388991376019616, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, xref=3., ext=[AuthorCompanyExt(id=1320388991384408225, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991376019616, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.School of Life Sciences, Peking University, Beijing 100871, China), AuthorCompanyExt(id=1320388991392796834, tenantId=1146029695717560320, journalId=1319373289681944729, articleId=1320388988398063764, companyId=1320388991376019616, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^3.北京大学生命科学学院，北京　100871)])], figs=null, attaches=null, journal=Journal(id=1319373034752147606, delFlag=0, nameCn=现代仪器与医疗, nameEn=Modern Instruments & Medical Treatment, nameHistory1=null, nameHistory2=null, issn=2095-5200, eissn=null, cn=10-1084/TH, coden=null, periodic=1, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=ndMvm7vxHT79E2yRWNKNzQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Modern Instruments & Medical Treatment, journalRemark=null, publicationField=null, createdTime=1792492644252, updatedTime=1792494001447, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=X, firstLetterEn=X, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=ndMvm7vxHT79E2yRWNKNzQ==, picEn=KKKOecvm1TyCdUk3lioBZw==, jcr=null, cjcr=null, exts=[JournalExt(id=1319378727318958500, language=CN, name=现代仪器与医疗, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1792494001464, updatedTime=1792494001464, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://xdyi.cbpt.cnki.net/editor/, submissionEditorUrl=https://xdyi.cbpt.cnki.net/editor/, submissionReviewUrl=https://xdyi.cbpt.cnki.net/editor/, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1319378727369290149, language=EN, name=Modern Instruments & Medical Treatment, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1792494001476, updatedTime=1792494001476, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=https://xdyi.cbpt.cnki.net/editor/, submissionEditorUrl=https://xdyi.cbpt.cnki.net/editor/, submissionReviewUrl=https://xdyi.cbpt.cnki.net/editor/, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1319373289681944729, websiteList=[Website(id=1319376331830313888, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1319373289681944729, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/xdyqyyl/CN, language=CN, createTime=1792493430335, createBy=18614031015, updateTime=1792493771498, updateBy=18614031015, name=现代仪器与医疗-中文, tplId=1146099689490845704, title=现代仪器与医疗, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1319377854559802284, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=articleTextType, value=kx, createTime=1792493793382, updateTime=1792493793382, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854522053545, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=banner, value=null, createTime=1792493793373, updateTime=1792493793373, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854597551023, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=grayFlag, value=0, createTime=1792493793391, updateTime=1792493793391, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854509470632, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=logo, value=https://castjournals.cast.org.cn/joweb/xdyqyyl/CN/file/pic?fileId=31v6dhjrP9Yy6tUJUZA+UQ==, createTime=1792493793370, updateTime=1792493793370, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854614328241, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=minRunFlag, value=0, createTime=1792493793395, updateTime=1792493793395, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854538830763, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/xdyqyyl/CN/file/pic, createTime=1792493793377, updateTime=1792493793377, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854605939632, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=silenceFlag, value=0, createTime=1792493793393, updateTime=1792493793393, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854530442154, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1792493793375, updateTime=1792493793375, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854568190893, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=themeColor, value=null, createTime=1792493793384, updateTime=1792493793384, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377854584968110, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376331830313888, code=themeStyle, value=null, createTime=1792493793388, updateTime=1792493793388, creator=18614031015, updator=18614031015)]), Website(id=1319376332157469608, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1319373289681944729, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/xdyqyyl/EN, language=EN, createTime=1792493430420, createBy=18614031015, updateTime=1792493768050, updateBy=18614031015, name=现代仪器与医疗-英文, tplId=1146101810881728533, title=Modern Instruments & Medical Treatment, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1319377880879059898, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=articleTextType, value=kx, createTime=1792493799657, updateTime=1792493799657, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880845505463, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=banner, value=null, createTime=1792493799649, updateTime=1792493799649, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880921002941, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=grayFlag, value=0, createTime=1792493799667, updateTime=1792493799667, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880832922550, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=logo, value=https://castjournals.cast.org.cn/joweb/xdyqyyl/EN/file/pic?fileId=31v6dhjrP9Yy6tUJUZA+UQ==, createTime=1792493799646, updateTime=1792493799646, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880937780159, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=minRunFlag, value=0, createTime=1792493799671, updateTime=1792493799671, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880866476985, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/xdyqyyl/EN/file/pic, createTime=1792493799654, updateTime=1792493799654, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880929391550, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=silenceFlag, value=0, createTime=1792493799669, updateTime=1792493799669, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880858088376, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1792493799652, updateTime=1792493799652, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880887448507, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=themeColor, value=null, createTime=1792493799659, updateTime=1792493799659, creator=18614031015, updator=18614031015), WebsiteProps(id=1319377880900031420, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1319376332157469608, code=themeStyle, value=null, createTime=1792493799662, updateTime=1792493799662, creator=18614031015, updator=18614031015)])], journalTitle=现代仪器与医疗, weixinUrl=null, journalUrl=https://xdyi.cbpt.cnki.net/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Modern Instruments & Medical Treatment, journalPhotoCn=ndMvm7vxHT79E2yRWNKNzQ==, journalPhotoEn=KKKOecvm1TyCdUk3lioBZw==, journalFirstLetter=X, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/xdyqyyl/CN/10.11876/mimt202504006, detailUrlEn=https://castjournals.cast.org.cn/joweb/xdyqyyl/EN/10.11876/mimt202504006, pdfUrlCn=https://castjournals.cast.org.cn/joweb/xdyqyyl/CN/PDF/10.11876/mimt202504006, pdfUrlEn=https://castjournals.cast.org.cn/joweb/xdyqyyl/EN/PDF/10.11876/mimt202504006, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1754755200000, fullTextJson=null, articleText=null, reference=null)