Article(id=1279144249295876966, tenantId=1146029695717560320, journalId=1279045329999892481, issueId=1279144148057960780, articleNumber=PA20260323_xN2DXr5V, orderNo=null, doi=10.19556/j.0258-7033.20250307-01, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1782901354383, onlineDateStr=2026-07-01, pubDate=1765468800000, pubDateStr=2025-12-12, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1782901354382, onlineIssueDateStr=2026-07-01, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1782901354382, creator=admin, updateTime=1782901354382, updator=admin, issue=Issue{id=1279144148057960780, tenantId=1146029695717560320, journalId=1279045329999892481, year='2026', volume='62', issue='2', pageStart='1', pageEnd='388', issueExtLink='null', onlineDate='null', pubDate='1770652800000', pubDateStr='2026-02-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1782901330245, creator='ztmeta', updateTime=1783650204703, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1282285155289108897, tenantId=1146029695717560320, journalId=1279045329999892481, issueId=1279144148057960780, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1282285155289108898, tenantId=1146029695717560320, journalId=1279045329999892481, issueId=1279144148057960780, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=121, endPage=127, ext={CN=ArticleExt(id=1284209626233160579, articleId=1279144249295876966, tenantId=1146029695717560320, journalId=1279045329999892481, language=CN, title=半番鸭不同羽色比较及其相关调控基因表达分析, columnId=1282278062347764011, journalTitle=中国畜牧杂志, columnName=遗传育种, runingTitle=null, highlight=null, articleAbstract=半番鸭是番鸭和家鸭的杂交后代，羽色是其重要包装性状，白羽性状可以保持胴体的美观度，并满足市场羽绒的加工需求。本研究采集8周龄半番鸭5个黑羽个体以及5个白羽个体背腹部毛囊组织，提取总RNA后进行转录组测序，比较分析不同羽色组别间的转录表达谱，对筛选到的差异表达基因进行GO和KEGG富集分析，qRT-PCR验证挑选的DEGs表达水平。以黑羽个体为对照组，黑羽组与白羽组间共鉴定到383个差异表达基因，其中219个上调基因和164下调基因，qRT-PCR结果显示，转录组测序结果准确可靠。GO富集分析结果表明，上述差异基因主要参与内皮素受体信号通路，其中TYR、KIT、MC1R、EDNRB2、ASIP、TYRP1和WNT8A基因显著影响黑色素的形成。KEGG富集分析结果表明，有7个差异表达基因与黑色素生成有关。结合GSEA分析和蛋白网络互作，其中TYR、KIT、MC1R、EDNRB2、ASIP、TYRP1和WNT8A基因与黑色素发生通路相关的差异基因被特别关注，表明这些基因与半番鸭的羽色发育有密切相关。本研究为了解半番鸭羽色发育的差异提供了依据，为其他家禽的羽色研究提供了参考。, authors=王逸飞^1,2, 周玮³, 朱春红^1,2, 王志成^1,2, 徐文娟^1,2, 曾涛⁴, 宋卫涛^1,2, 顾昊天^1,2, 陶志云^1,2, 章双杰^1,2, 李慧芳^1,2, 刘宏祥^1,2, authorsList=王逸飞, 周玮, 朱春红, 王志成, 徐文娟, 曾涛, 宋卫涛, 顾昊天, 陶志云, 章双杰, 李慧芳, 刘宏祥, authorCompany=1.中国农业科学院家禽研究所;
2.江苏省家禽科学研究所;
3.江苏桂柳牧业集团有限公司;
4.浙江省农业科学院畜牧兽医研究所农产品质量安全危害因子与风险防控国家重点实验室, correspAuthors=刘宏祥, authorNote=王逸飞（2000-），男，河南平顶山人，在读硕士研究生，研究方向：家禽遗传育种，E-mail:YifeiWWWWWW@126.com; 周玮（1988-），女，广西桂林人，畜牧师，研究方向：家禽生产与健康养殖，E-mail:glyzzj2018@163.com;, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=Xsy1xvFYTg6u2Nw57ETI5Q==, pdfFileSize=2477732, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=江苏省“种业振兴”揭榜挂帅项目（JBGS[2021]111,JBGS[2021]030）;扬州市现代农业项目（YZ2024054）;扬州市自然科学基金（YZ2023167）;“天池英才”引进计划;)}, authors=null, keywords=[Keyword(id=1284217189800592209, tenantId=1146029695717560320, journalId=1279045329999892481, articleId=1279144249295876966, language=CN, orderNo=1, keyword=羽色), Keyword(id=1284217189892866898, tenantId=1146029695717560320, 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