中国畜牧杂志

鱼腥草及其提取物在畜禽饲粮中的应用研究进展

PDF下载

中国畜牧杂志 | 综述 2026,62(2): 44-54

收起

中国畜牧杂志 |综述 2026 , 62 (2) : 44 -54

鱼腥草及其提取物在畜禽饲粮中的应用研究进展

全屏

冯伦杰¹, 汤华玉¹, 吴天赐¹, 陈玲², 陈帅³, 陈莉文³, 蒋成全², 严鸿林¹

作者信息

通讯作者:

蒋成全

作者简介:

冯伦杰（1999-），男，四川宜宾人，硕士研究生，主要从事动物营养与饲料科学研究，E-mail:lunjiefeng2023@163.com;

Affiliations

出版时间: 2025-12-24 doi: 10.19556/j.0258-7033.20250329-01

文章导航

摘要

收起

鱼腥草在中医中具有悠久的药用历史，具有抗炎、抗菌、抗病毒、利尿、抗氧化和抗肿瘤的作用，这与其富含生物碱、挥发油、酚酸和类黄酮等多种生物活性物质有关。自我国饲料端禁用抗生素以来，鱼腥草与其提取物作为潜在的抗生素替代品受到了广泛关注。目前，关于鱼腥草与其提取物对畜禽生长和健康有益效果的研究日益增多，但其活性成分复杂、作用机制不明以及在畜禽饲粮中的应用潜力尚未得到充分挖掘。本文综述了鱼腥草与其提取物的生物学活性以及在畜禽饲粮中的应用及可能机制，以期为鱼腥草与其提取物在畜禽饲粮中的高效合理利用提供一定理论依据和参考。

关键词

饲粮 / 鱼腥草 / 鱼腥草提取物 / 生物学功能

引用本文

冯伦杰, 汤华玉, 吴天赐, 陈玲, 陈帅, 陈莉文, 蒋成全, 严鸿林. 鱼腥草及其提取物在畜禽饲粮中的应用研究进展. 中国畜牧杂志, 2026 , 62 (2) : 44 -54 . DOI: 10.19556/j.0258-7033.20250329-01

基金

收起

中央引导地方科技发展项目(2022ZYDF081);

参考文献

收起

文献

收起

参考文献引证文献

排序方式：

[1]Rafiq S, Hao H, Ijaz M, et al. Pharmacological effects of Houttuynia cordata Thunb(H. cordata):a comprehensive review[J].Pharmaceuticals, 2022, 15(9):1079-1088.
[2]Tabashsum Z, Scriba A, Biswas D. Alternative approaches to therapeutics and subtherapeutics for sustainable poultry production[J]. Poult Sci, 2023, 102(7):102750.
[3]董晨扬,魏曼琳,张航,等.植物提取物在动物生产中的研究进展[J].饲料研究, 2022, 45(4):136-139.
[4]Wei P, Luo Q, Hou Y, et al. Houttuynia Cordata Thunb:a comprehensive review of traditional applications, phytoch-emistry,pharmacology and safety[J]. Phytomedicine, 2024, 123(1):155195.
[5]Wu Z, Deng X, Hu Q, et al. Houttuynia cordata Thunb:an ethnopharmacological review[J]. Front Pharmacol, 2021, 12(1):714694.
[6]Ahn J, Chae H, Chin Y, et al. Alkaloids from aerial parts of Houttuynia cordata and their anti-inflammatory activity[J].Bioorg Med Chem Lett, 2017, 27(12):2807-2811.
[7]吴丽萍,徐纪英.复方鱼腥草合剂治疗急性咽炎疗效观察及对血清炎症因子、免疫功能的影响[J].新中医, 2024, 56(8):111-115.
[8]Ghosh A, Ghosh B, Parihar N, et al. Nutraceutical prospects of Houttuynia cordata against the infectious viruses[J]. Food Biosci, 2022, 50(1):101977.
[9]Cao G, Liu J, Liu H, et al. Integration of network pharmacology and molecular docking to analyse the mechanism of action of oregano essential oil in the treatment of bovine mastitis[J]. Vet Sci, 2023, 10(5):350-362.
[10]Yu-Syuan L I, Kuan-Hung L, Chun-Wei W U, et al. Effects of temperatures on growth, physiological, and antioxidant characteristics in Houttuynia cordata[J]. Not Bot Horti Agrobo,2021, 49(4):12536.
[11]Pang J, Dong W, Li Y, et al. Purification of Houttuynia cordata Thunb. essential oil using macroporous resin followed by microemulsion encapsulation to improve its safety and antiviral activity[J]. Molecules, 2017, 22(2):293-309.
[12]Gurung A B, Ali M A, Lee J, et al. Identification of SARSCoV-2 inhibitors from extracts of Houttuynia cordata Thunb[J].Saudi J Biol Sci, 2021, 28(12):7517-7527.
[13]Pham H G, Ha M T, Cao T Q, et al. Alkaloids from Houttuynia cordata Thunb. and their chemotaxonomic significance[J].Biochem Syst Ecol, 2023, 109(1):104665.
[14]Zhang C, Shi L, Wang F S. Liver injury in COVID-19:management and challenges[J]. Lancet Gastroenterol, 2020, 5(5):428-430.
[15]Lu Y, Zhang J J, Huo J Y, et al. Structural characterization and anti-complementary activities of two polysaccharides from Houttuynia cordata[J]. Planta Med, 2019, 85(13):1098-1106.
[16]Ahn J, Kim J. Chemical constituents from Houttuynia cordata[J]. Planta Med, 2016, 82(S1):P309.
[17]Quan W X, Wei X F, Yang Z N, et al. Effects of 6-benzyladenine and kinetin on growth and secondary metabolites of Houttuynia cordata Thunb.(Saururaceae)[J]. Pak J Bot, 2021,53(4):1219-1225.
[18]Hamed M, Abdallah I A, Bedair A, et al. Sample preparation methods for determination of quercetin and quercetin glycosides in diverse matrices[J]. Microchem J, 2023, 194(1):109233.
[19]Tang J, Diao P, Shu X, et al. Quercetin and quercitrin attenuates the inflammatory response and oxidative stress in LPS-induced RAW264. 7 cells:In vitro assessment and a theoretical model[J]. Biomed Res Int, 2019, 2019(1):7039802.
[20]Imani A, Maleki N, Bohlouli S, et al. Molecular mechanisms of anticancer effect of rutin[J]. Phytother Res, 2021, 35(5):2500-2513.
[21]Yang W, Tu H, Tang K, et al. Reynoutrin improves ischemic heart failure in rats via targeting S100A1[J]. Front Pharmacol,2021, 12(1):703962.
[22]Song H, Shen T, Wu J, et al. Extraction and activity of chemical constituents from Houttuynia cordata Thunb by ultrasonic method[J]. Cell Mol Biol, 2021, 67(6):281-290.
[23]Chen M X, Haider M K, Kim I S, et al. Characterization of antioxidant Houttuynia cordata extracts loaded polyurethane nanofibers[J]. Fash Text, 2023, 10(1):1-17.
[24]Nguyen V T, Le V M, Vo T S, et al. Preliminary phytochemical screening and determination of total polyphenols and flavonoids content in the leaves of Houttuynia cordata Thunb:IOP conference series[J]. Mater Sci Eng A, 2020, 736(6):062013.
[25]李静,陈长勋,高阳,等.鱼腥草素抗炎与抗动脉硬化作用的探索[J].中成药, 2010(1):26-30.
[26]Xu X, Liu S, Zhao Y, et al. Combination of Houttuynia cordata polysaccharide and Lactiplantibacillus plantarum P101alleviates acute liver injury by regulating gut microbiota in mice[J]. J Sci Food Agr, 2022, 102(15):6848-6857.
[27]Li T, Sang T, Song Y, et al. Houttuynia cordata polysaccharide alleviates chronic vascular inflammation by suppressing calcium-sensing receptor in rats[J]. J Funct Foods, 2022, 95(1):105172.
[28]Yang Z, Ji P, Li C, et al. Research progress on the chemical constituents and pharmacological effects of houttuynia cordata thunb and a predictive analysis of quality markers[J]. Curr Issues Mol Biol, 2024, 47(1):18-41.
[29]吴苹,刘晋倩,董晶,等.鱼腥草多糖对DSS诱导小鼠结肠炎的改善作用[J].食品工业科技, 2021, 42(23):362-369.
[30]Wang C, Huang C, Li M. Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/rorγ t expression and reversing Treg/Th17 cell imbalance[J]. Int Immunopharmacol, 2022, 103(1):108487.
[31]Yu M, Wang L, Luo H, et al. Zebrafish as a promising model for investigating biological activities of ginseng species—a review[J]. Qual Assur Saf Crop, 2024, 16(1):38-59.
[32]Saadat S, Beigoli S, Khazdair M R, et al. Experimental and clinical studies on the effects of natural products on noxious agents-induced lung disorders, a review[J]. Front Nutr, 2022,9(1):867914.
[33]Sumneang N, Kobroob A, Phungphong S, et al. Fermented Houttuynia cordata juice exerts cardioprotective effects by aleviating cardiac inflammation and apoptosis in rats with lipopolysaccharide-induced sepsis[J]. Nutrients, 2025, 17(3):501-515.
[34]Liu J, Zou J, Wang J, Wang R, et al. Extraction, purification,structural features, and pharmacological properties of polysaccharides from Houttuynia cordata:A review[J]. Int J Biol Macromol, 2024, 279(1):135230.
[35]Wang Y, Shen X, Yin K, et al. Structural characteristics and immune-enhancing activity of fractionated polysaccharides from Athyrium Multidentatum(Doll.)Ching[J]. Int J Biol Macromol, 2022, 205(1):76-89.
[36]Gururuloo S L, Shahpudin S N M, Sandai D A, et al. anticancer properties of locally available natural products in malaysia against colorectal cancer[J]. Jummec, 2023(1):23-35.
[37]Vo T S. Natural products targeting FcεRI receptor for antiallergic therapeutics[J]. J Food Biochem, 2020, 44(8):e13335.
[38]Yang Y, Wang L, Zhao B, et al. Chemical compositions of Houttuynia cordata Thunb. volatile oil and its analogues attenuate Staphylococcus aureus virulence by targeting α-hemolysin[J]. Russ J Bioorg Chem, 2022, 48(1):166-177.
[39]ŘebíčkováK, Bajer T,Šilha D, et al. Chemical composition and determination of the antibacterial activity of essential oils in liquid and vapor phases extracted from two different southeast Asian herbs—Houttuynia cordata(saururaceae)and Persicaria odorata(polygonaceae)[J]. Molecules, 2020, 25(10):2432-2442.
[40]Liang J, Huang X, Ma G. Antimicrobial activities and mechanisms of extract and components of herbs in East Asia[J]. Rsc Adv, 2022, 12(45):29197-29213.
[41]Laldinsangi C. The therapeutic potential of Houttuynia cordata:A current review[J]. Heliyon, 2022, 8(8):e10386.
[42]Pan F, Liu Z, Chen Q, et al. Endophytic fungus strain 28isolated from Houttuynia cordata possesses wide-spectrum antifungal activity[J]. Braz J Microbiol, 2016, 47(2):480-488.
[43]Ye H, Luo S, Yang Z, et al. Latent pathogenic fungi in the medicinal plant Houttuynia cordata Thunb. Are modulated by secondary metabolites and colonizing microbiota originating from soil[J]. Pol J Microbiol, 2021, 70(3):359-372.
[44]Maimaiti X, Bassey A P, Liu X, et al. Green synthesis of silver nanoparticles using Houttuynia cordata Thunb rhizome extracts and their antibacterial potential against common foodborne pathogens[J]. Int J Food Sci Tech, 2024, 59(5):3283-3296.
[45]Cheng T, Xu C, Wu D, et al. Sodium houttuyfonate derived from Houttuynia cordata Thunb improves intestinal malfunction via maintaining gut microflora stability in Candida albicans overgrowth aggravated ulcerative colitis[J]. Food Function,2023, 14(2):1072-1086.
[46]Cen L F, Yi T, Hao Y Z, et al. Houttuynia cordata polysaccharides alleviate ulcerative colitis by restoring intestinal homeostasis[J]. Chin J Nat Medicines, 2022, 20(12):914-924.
[47]Wang S, Li L, Chen Y, et al. Houttuynia cordata thunb. alleviates inflammatory bowel disease by modulating intestinal microenvironment:a research review[J]. Front Immunol, 2023,14(1):1306375.
[48]Lin R, Piao M, Song Y. Dietary quercetin increases colonic microbial diversity and attenuates colitis severity in Citrobacter rodentium-infected mice[J]. Front Microbiol, 2019, 10(1):1092-1100.
[49]Nie J, Zhang L, Zhao G, et al. Quercetin reduces atherosclerotic lesions by altering the gut microbiota and reducing atherogenic lipid metabolites[J]. J Appl Microbiol, 2019, 127(6):1824-1834.
[50]Li Q, Wu Y, Qi X, et al. Prickly ash seeds improve the ruminal epithelial development and growth performance of Hu sheep by modulating the rumen microbiota and metabolome[J].Microorganisms, 2024, 12(11):2242-2260.
[51]Chang K, Lin T Y, Fu S L, et al. A houttuynia cordata–based Chinese herbal formula improved symptoms of allergic rhinitis during the COVID-19 pandemic[J]. J Chin Med Assoc, 2022,85(6):717-722.
[52]Tuyen P T, Anh T T T, Trang P T, et al. Antioxidant properties and total phenolic contents of various extracts from Houttuynia cordata Thunb[J]. Acad J Biol, 2018, 40(2se):149-154.
[53]Shingnaisui K, Dey T, Manna P, et al. Therapeutic potentials of houttuynia cordata Thunb. against inflammation and oxidative stress:a review[J]. J Ethnopharmacol, 2018, 220(1):35-43.
[54]Park M H, Kim B. Antioxidant and anti-wrinkle effects of fermented Houttuynia cordata extract[J]. Food Sci Preserv,2025, 32(2):280-288.
[55]Ling L, Lu Y, Zhang Y, et al. Flavonoids from Houttuynia cordata attenuate H1N1-induced acute lung injury in mice via inhibition of influenza virus and Toll-like receptor signalling[J].Phytomedicine, 2020, 67:153150.
[56]Devi A B, Sarala R. Substantial effect of phytochemical constituents against the pandemic disease influenza—a review[J].Futur J Pharm Sci, 2021 ,7(1):120-152.
[57]Dhiman M, Sharma L, Dadhich A, et al. Traditional knowledge to contemporary medication in the treatment of infectious disease dengue:a review[J]. Front Pharmacol, 2022, 13:750494.
[58]Ruansit W, Charerntantanakul W. Oral supplementation of Houttuynia cordata extract reduces viremia in PRRSV-1 modified-live virus-vaccinated pigs in response to the HP-PRRSV-2challenge[J]. Front Immunol, 2022, 13:929338.
[59]Yasmin A R, Chia S L, Looi Q H, et al. Herbal extracts as antiviral agents[M]. Feed Additives, 2020(1):115-132.
[60]Wu Y, Li N, Zhang T, et al. Glycyrrhiza polysaccharides can improve and prolong the response of chickens to the Newcastle disease vaccine[J]. Poult Sci, 2022, 101(1):101549.
[61]Yüce F N, YörüH B, Acar G, et al. Herpesviral infections of the nervous system in ruminants:BoHV-1, BoHV-5, MCFV,PRV[J]. Curr Vet Sci, 2025, 2(1):11-18.
[62]Saleh M S, Kamisah Y. Potential medicinal plants for the treatment of dengue fever and severe acute respiratory syndromecoronavirus[J]. Biomolecules, 2021, 11(1):42.
[63]Liu Y, Jiang Y, Yang Y, et al. Houttuynia essential oil and its self-microemulsion preparation protect against LPS-induced murine mastitis by restoring the blood-milk barrier and inhibiting inflammation[J]. Front Immunol, 2022, 13:842189.
[64]司雨豪.鱼腥草对断奶清平仔猪生长性能、血液理化指标与肠道健康的影响[D].武汉:华中农业大学, 2024.
[65]Ma J, Long S, Wang J, et al. Microencapsulated essential oils combined with organic acids improves immune antioxidant capacity and intestinal barrier function as well as modulates the hindgut microbial community in piglets[J]. J Anim Sci Biotechno, 2022, 13(1):16-32.
[66]Huang X L, Yu P, Luo Y H, et al. The nutritional value, application status and challenges of Houttuynia cordata Thunb(H.cordata)[J]. Phytochem Rev, 2025, 10(1):1-23.
[67]Li Z H, Cao H, Cheng Y F, et al. Inhibition of porcine epidemic diarrhea virus replication and viral 3C-like protease by quercetin[J]. Int J Mol Sci, 2020, 21(21):1-13.
[68]Wang N, Zhu Y, Li D, et al. 2-methyl nonyl ketone from Houttuynia cordata thunb alleviates LPS-induced inflammatory response and oxidative stress in bovine mammary epithelial cells[J]. Front Chem, 2022, 9(1):793475.
[69]赵桂新,付祥,王凤杰,等. 5种中药体外抗牛传染性鼻气管炎病毒作用方式的研究[J].中国预防兽医学报, 2023, 45(8):846-852.
[70]Liu S Q, Li S H, Huang S C, et al. Exploring the anticoccidial efficacy of Houttuynia cordata:Insights into gut microbiota modulation and metabolic enhancement in lambs[J]. Res Vet Sci, 2025, 194:105821.
[71]Yu S, Li L, Zhao H, et al. Dietary citrus flavonoid extract improves lactational performance through modulating rumen microbiome and metabolites in dairy cows[J]. Food Funct,2023, 14(1):94-111.
[72]Singh S, Hundal J S, Patra A K, et al. A composite polyphenolrich extract improved growth performance, ruminal fermentation and immunity, while decreasing methanogenesis and excretion of nitrogen and phosphorus in growing buffaloes[J].Environ Sci Pollut R, 2022, 29(17):24757-24773.
[73]Odhaib K J, Al-Hajjar Q N, Alallawee M H. Incorporation of herbal plants in the diet of ruminants:Effect on meat quality[J].Iraqi J Vet Med, 2021, 45(1):22-30.
[74]Ha N C, Thuy N T, Phuong L T. Effect of adding Houttuynia cordata and Perilla frutescens leaves powders in diets on growth, intestinal microflora and meat quality of local chickens in Vietnam[J]. Vet Integr Sci, 2025, 23(2):1-9.
[75]Yu A, Wang M, Chen L, et al. Effects of dietary pretreated Chinese herbal medicine supplementation on production performance, egg quality, uterine histopathological changes,and antioxidant capacity in late-phase laying hens[J]. Front Physiol, 2023, 14(1):1110301.
[76]Lee H, Kim O. Anticoccidial effects of the Houttuynia cordata extract on experimental animal infection model[J]. J Biomed Transl Res, 2022, 23(1):29-33.
[77]Wang Y, Liang Y, Hu F, et al. Chinese herbal formulae defend against Mycoplasma gallisepticum infection[J]. J Integr Agr,2022, 21(10):3026-3036.
[78]Jang W W, Chung T H, Choi I H. Dietary Houttuynia cordata/fermented red koji blends to improve duck growth performance and alum blends addition to reduce litter ammonia concentration[J]. Adv Anim Vet Sci, 2019, 7(12):1101-1106.
[79]Jeong Y. Evaluation of blood profile and meat color using houttuynia cordata pellet in duck diets[J]. J Environ Sci Int,2021, 30(5):425-428.."

2026年第62卷第2期

PDF下载

引用本文

BibTeX

文章信息

doi: 10.19556/j.0258-7033.20250329-01

首发时间：2026-07-01
出版时间：2025-12-24

补充材料

相关文章

文章信息

作者

出版历史

基金

作者信息

参考文献

分享链接

https://castjournals.cast.org.cn/joweb/zgxmzz/CN/10.19556/j.0258-7033.20250329-01

分享至

全文二维码

扫描看全文

引用本文

BibTeX

本文的引用情况

2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

关闭全屏

BibTeX
EndNote
RefWorks
TxT