中国畜牧杂志

非编码RNA调控家畜肌肉生长发育的分子机制

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魏亚丽, 房华, 王永飞, 董宇, 李舜, 林正辉, 托合提麦麦提·努日, 张云峰

中国畜牧杂志 | 综述 2026,62(2): 103-111

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中国畜牧杂志 |综述 2026 , 62 (2) : 103 -111

非编码RNA调控家畜肌肉生长发育的分子机制

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魏亚丽, 房华, 王永飞, 董宇, 李舜, 林正辉, 托合提麦麦提·努日, 张云峰

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作者简介:

魏亚丽(1999-),女,硕士,助理研究员,主要从事动物遗传育种研究,E-mail:3098761734@qq.com;

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出版时间: 2026-01-08 doi: 10.19556/j.0258-7033.20250529-07

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家畜肌肉生长速度、产量及肉品质直接关系到畜牧业的经济效益，因此，骨骼肌发育研究对畜牧业生产具有重要意义。近年来，随着测序技术和组学技术的不断进步，研究人员在肌肉细胞中鉴定出了大量非编码RNA(ncRNA)。ncRNA具有生物学功能但不参与蛋白质翻译，主要包括微小RNA(microRNA,miRNA)、长链非编码RNA(long non-coding RNA,lncRNA)和环状RNA(circular RNA,circRNA)，这些ncRNA通过多种调控机制在转录后水平调控肌肉生长发育关键基因，进而影响肌细胞的数量和体积，最终决定肌肉质量。本文综述了参与肌肉生长发育调控的候选ncRNA(miRNA、lncRNA和circRNA)及其相关基因、调控机制和相关信号通路（如Wnt、PI3K/Akt通路），旨在为进一步阐明ncRNA在家畜肌肉生长发育中的分子调控机制提供理论参考。

关键词

肌肉生长发育 / miRNAs / lncRNAs / circRNAs

引用本文

魏亚丽, 房华, 王永飞, 董宇, 李舜, 林正辉, 托合提麦麦提·努日, 张云峰. 非编码RNA调控家畜肌肉生长发育的分子机制. 中国畜牧杂志, 2026 , 62 (2) : 103 -111 . DOI: 10.19556/j.0258-7033.20250529-07

基金

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兵团科技计划项目支持（2024CC006）;新疆农垦科学院青年基金项目（2025YJQN19）;新疆农垦科学院农业科技创新工程（NCG202313）;

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2026年第62卷第2期

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doi: 10.19556/j.0258-7033.20250529-07

首发时间：2026-07-01
出版时间：2026-01-08

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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