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[26]刘之园,贾俊霞,姜昊蔚,等.耐酸耐胆盐益生菌的筛选及其益生特性研究[J].中国酿造, 2020, 39(11):103-108.
[27]陈仪婷,张红星,谢远红,等.降胆固醇乳酸菌的筛选鉴定及其耐酸耐胆盐性能研究[J].食品与发酵工业, 2018, 44(5):29-33.
[28]Ru X, Zhang C C, Yuan Y H, et al. Bile salt hydrolase activity is present in nonintestinal lactic acid bacteria at an intermediate level[J]. Appl Microbiol Biotechnol, 2019, 103:893-902.
[29]Zhang L, Ma H, Kulyar M F A, et al. Complete genome analysis of Lactobacillus fermentum YLF016 and its probiotic characteristics[J]. Microb Pathogenesis, 2022, 162:105212.
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[33]代玉明,黄涛,熊涛.鸡源凝结芽孢杆菌的筛选鉴定及益生性能评价[J].南昌大学学报(理科版), 2022, 46(4):464-472, 480.
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[39]刘淑杰,邓波,吴杰,等. ZEN污染饲料中添加植物炭黑对大鼠脏器组织、抗氧化指标及免疫功能的影响[J].中国畜牧杂志, 2022, 58(1):225-230.
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中国畜牧杂志 | 动物健康 2026,62(2): 317-324
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中国畜牧杂志 |动物健康 2026 , 62 (2) : 317 -324
玉米赤霉烯酮降解菌的分离鉴定、益生特性及其对中毒小鼠的缓解作用研究
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张启航1, 吴慧昊2, 陈文燕1, 周瑞1,3, 李耀东1, 臧荣鑫1, 徐红伟1
作者信息
    1.西北民族大学生命科学与工程学院;
    2.西北民族大学实验教学部;
    3.西北民族大学生物技术与生物工程国家民委重点实验室
通讯作者:
臧荣鑫
作者简介:
张启航(1999-),男,山东济南人,硕士,主要从事肠道菌群与健康研究,E-mail:1614427745@qq.com;
  • Affiliations
    出版时间: 2025-12-19 doi: 10.19556/j.0258-7033.20250120-04
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    本研究旨在分离筛选出具有体外降解玉米赤霉烯酮(Zearalenone,ZEN),且具备良好益生性的枯草芽孢杆菌,并评估其缓解小鼠ZEN中毒症状的能力,为其作为饲料添加剂和霉菌毒素脱毒菌剂提供参考依据。从牡丹根际土壤样品中,分离纯化对ZEN具有降解能力的益生菌并探究菌株益生性能。将30只雌鼠随机分为3组,每组10只,每组平均体重25~28 g,对照组小鼠灌服生理盐水,ZEN组灌服ZEN标准品稀释液(50 mg/kg BW),H-1组灌服ZEN标准品稀释液(50 mg/kg BW)与H-1培养液(1×10~8 CFU/mL),每只小鼠灌服剂量为0.2 mL,检测各组生长性能、脏器指标和肝脏与生殖系统相关指标。结果表明:枯草芽孢杆菌H-1玉米赤霉烯酮体外降解率可达88.3%,并且有较好的益生性与安全性。与ZEN组相比,H-1菌株对ZEN造成的生长性能影响有改善作用(P<0.05);同时,与ZEN组相比,H-1组子宫卵巢系数降低(P<0.05),促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E 2 )含量升高(P>0.05),谷丙转氨酶(ALT)、谷草转氨酶(AST)水平降低(P<0.05)。分离所得枯草芽孢杆菌H-1具有体外降解玉米赤霉烯酮的能力与良好的益生性能,可缓解玉米赤霉烯酮中毒对小鼠肝脏及生殖系统造成的损伤。
    枯草芽孢杆菌  /  分离鉴定  /  益生性  /  玉米赤霉烯酮
    张启航, 吴慧昊, 陈文燕, 周瑞, 李耀东, 臧荣鑫, 徐红伟. 玉米赤霉烯酮降解菌的分离鉴定、益生特性及其对中毒小鼠的缓解作用研究. 中国畜牧杂志, 2026 , 62 (2) : 317 -324 . DOI: 10.19556/j.0258-7033.20250120-04

      甘肃省科技计划项目(24ZDNA004、24YFWA016);西北民族大学中央高校基本科研业务费专项资金(31920210060、31920210004);

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    2种不同金属材料的力学参数

    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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