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This paper systematically elaborated the mechanisms through which heat stress affects dairy cows, with a focus on the scientific application strategies of reproductive hormones (such as GnRH and progesterone), glucocorticoids (such as dexamethasone), and melatonin in alleviating heat stress. Practical cases from dairy farms in both northern and southern regions demonstrate the effectiveness of hormonal regulation in enhancing stress resistance,improving reproductive efficiency, and restoring production performance. The study emphasized that hormone use should adhere to the principles of short-term and low-dose application, combined with comprehensive measures such as physical cooling and nutritional adjustments, to ensure dairy product safety and farming profitability. 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articleAbstract=热应激对奶牛生产性能、繁殖功能及免疫系统造成显著负面影响,导致产奶量下降15%~20%、受胎率降低25%~35%,并引发多种健康问题。本文系统阐述了热应激对奶牛的影响机制,重点探讨了生殖激素(如GnRH、孕酮)、糖皮质激素(如地塞米松)及褪黑激素等在缓解热应激中的科学应用策略。结合南北地区牧场实际案例,验证了激素调控在提升奶牛抗应激能力、改善繁殖效率及恢复生产性能方面的有效性。研究强调,激素使用应遵循短期、低剂量原则,并配合物理降温和营养调控等综合措施,以确保乳品安全与养殖效益。本文为奶牛场应对热应激提供了理论依据与实践指导。, authors=赵新春, authorsList=赵新春, authorCompany=曹县畜牧服务中心,山东菏泽 274400, correspAuthors=null, authorNote=赵新春(1970-),男 ,山东曹县人,本科,畜牧师,研究方向为畜牧兽医技术。, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=ltylDqfzD48zAPA6PdczmA==, pdfFileSize=1282376, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1321421051762946645, tenantId=1146029695717560320, journalId=1296801528146919473, 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[13] De Rensis F,Scaramuzzi R J.Heat stress and seasonal effects on reproduction in the dairy cow—a review[J].Theriogenology,2003,60(6):1139-1151. [14] García-Ispierto I,López-Gatius F,Bech-Sabat G,et al.Climate factors affecting conception rate of high producing dairy cows in northeastern Spain[J].Theriogenology,2007,67(8):1379-1385. [15] Sheldon I M,Dobson H. Postpartum uterine health in cattle[J].Animal Reproduction Science,2004,82-83:295-306. [16] Rhoads M L,Rhoads R P,Vanbaale M J,et al.Effects of heat stress and plane of nutrition on lactating Holstein cows:I. Production,metabolism,and aspects of circulating somatotropin[J].Journal of Dairy Science,2009,92(5):1986-1997. [17] Harper M E,Seifert E L.Thyroid hormone effects on mitochondrial energetics[J]. Thyroid,2008,18(2):145-156. [18] Kadzere C T,Murphy M R,Silanikove N,et al.Heat stress in lactating dairy cows: a review[J].Livestock production science,2002,77(1):59-91. [19] 程广龙. 奶牛热应激的发生及减缓措施[J].安徽农业科学,2008,36(7):2797-2798. [20] 边小娜,张家新.褪黑激素抗氧化作用的研究进展[J].安徽农学通报,2017,23(9):24-27. [21] 李卫群,陈钟英,周瑶玺.免疫调节中白细胞介素2和γ-干扰素的相互关系[J].国外医学(免疫学分册),1986(6):312-315. [22] 杨利国. 下丘脑促性腺激素释放激素的神经内分泌调节[J].黑龙江动物繁殖,1995(4): 39-41. [23] 田文儒,胡庆德,李俊伟,等.前列腺素F2α对产后奶牛繁殖性能影响的研究[J].辽宁畜牧兽医,1993(4):7-9. [24] López-Gatius F,López-Béjar M,Fenech M,et al.Ovulation failure and double ovulation in dairy cattle:risk factors and effects[J].Theriogenology,2005, 63(5):1298-1307. [25] Pugliesi G,Santos F B,Lopes E,et al.Improved fertility in suckled beef cows ovulating large follicles or supplemented with long-acting progesterone after timed-AI[J].Theriogenology,2016,85(7):1239-1248. [26] Bech-Sabat G,López-Gatius F,Yániz J L,et al.Factors affecting plasma progesterone in the early fetal period in high producing dairy cows[J]. Theriogenology,2008,69(4):426-432. [27] Friedman E,Voet H,Reznikov D,et al.Hormonal treatment before and after artificial insemination differentially improves fertility in subpopulations of dairy cows during the summer and autumn[J].Journal of Dairy Science,2014,97(12): 7465-7475. [28] 陈仗榴. 兽医药理学[M].北京:中国农业出版社,2002. [29] 谭健,余诗强,赵玉超,等.糖皮质激素与热应激奶牛免疫系统互作机制的研究进展[J]. 动物营养学报,2023,35(9):5496-5504. [30] 李瑾,曾晓.地塞米松的作用及在奶牛疾病治疗中的禁忌[J].畜牧兽医科学(电子版), 2019(7):47-48. [31] Li Z Q,Zhang K Y,Zhou Y M,et al.Role of melatonin in bovine reproductive biotechnology[J].Molecules,2023,28(13):4940. [32] Gao Y J,Li Y N,Wang J M,et al.Melatonin alleviates lipopolysaccharide-induced endometritis by inhibiting the activation of NLRP3 inflammasome through autophagy[J].Animals,2023,13(15):2449. [33] Zhao X M,Wang N,Hao H S,et al.Melatonin improves the fertilization capacity and developmental ability of bovine oocytes by regulating cytoplasmic maturation events[J]. Journal of Pineal Research,2018,64(1):e12445. [34] Ahmad S B,Ali A,Bilal M,et al.Melatonin and health:Insights of melatonin action,biological functions,and associated disorders[J].Cellular and Molecular Neurobiology,2023,43(6):2437-2458. [35] Brockus K E,Hart C G,Gilfeather C L,et al.Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers[J].Domestic animal endocrinology,2016,55:1-10. [36] Ratchanak R,Thananurak P,Boonkum W,et al.The melatonin treatment improves the ovarian responses after superstimulation in Thai-Holstein crossbreeds under heat stress conditions[J].Frontiers in Veterinary Science,2022,9:888039. [37] 孙伟,郭雅欣,王超,等.褪黑素对高产荷斯坦奶牛体外胚胎生产质量及效率的影响[J].中国畜牧杂志,2025:1-8. [38] 戴艳菲,王弘浩,张瑞,等.维生素缓解奶牛热应激的研究进展[J].家畜生态学报,2025,46(5):5-10.)
中国乳业
|奶牛繁殖健康管理专栏
2025
,
(8) :
8
-14
热应激下奶牛激素调控策略及其应用效果分析
全屏
赵新春
作者信息
作者简介:
赵新春(1970-),男 ,山东曹县人,本科,畜牧师,研究方向为畜牧兽医技术。
Regulation Strategies and Application Effects of Hormones in Dairy Cows under Heat Stress
ZHAO Xinchun
Affiliations
Animal Husbandry Service Center of Cao County, Heze Shandong 274400
doi: 10.12377/1671-4393.25.08.02
文章导航
热应激对奶牛生产性能、繁殖功能及免疫系统造成显著负面影响,导致产奶量下降15%~20%、受胎率降低25%~35%,并引发多种健康问题。本文系统阐述了热应激对奶牛的影响机制,重点探讨了生殖激素(如GnRH、孕酮)、糖皮质激素(如地塞米松)及褪黑激素等在缓解热应激中的科学应用策略。结合南北地区牧场实际案例,验证了激素调控在提升奶牛抗应激能力、改善繁殖效率及恢复生产性能方面的有效性。研究强调,激素使用应遵循短期、低剂量原则,并配合物理降温和营养调控等综合措施,以确保乳品安全与养殖效益。本文为奶牛场应对热应激提供了理论依据与实践指导。
Heat stress exerts significant negative impacts on the production performance, reproductive function, and immune system of dairy cows, leading to a 15%~20% decrease in milk yield, a 25%~35% reduction in conception rate, and various health disorders. This paper systematically elaborated the mechanisms through which heat stress affects dairy cows, with a focus on the scientific application strategies of reproductive hormones (such as GnRH and progesterone), glucocorticoids (such as dexamethasone), and melatonin in alleviating heat stress. Practical cases from dairy farms in both northern and southern regions demonstrate the effectiveness of hormonal regulation in enhancing stress resistance,improving reproductive efficiency, and restoring production performance. The study emphasized that hormone use should adhere to the principles of short-term and low-dose application, combined with comprehensive measures such as physical cooling and nutritional adjustments, to ensure dairy product safety and farming profitability. This paper provides a theoretical basis and practical guidance for dairy farms to mitigate heat stress.
heat stress
/
dairy cows
/
hormone application
/
management strategies
赵新春.
热应激下奶牛激素调控策略及其应用效果分析.
中国乳业,
2025
,
(8)
: 8
-14
.
DOI: 10.12377/1671-4393.25.08.02
ZHAO Xinchun.
Regulation Strategies and Application Effects of Hormones in Dairy Cows under Heat Stress[J].
China Dairy ,
2025
,
(8)
: 8
-14
.
DOI: 10.12377/1671-4393.25.08.02
参考文献
引证文献
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2025年第卷第8期
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doi: 10.12377/1671-4393.25.08.02
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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