Article(id=1297139238940729924, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297139203754709410, articleNumber=null, orderNo=null, doi=10.12377/1671-4393.26.06.02, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1787191694245, onlineDateStr=2026-08-20, pubDate=1782316800000, pubDateStr=2026-06-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1787191694245, onlineIssueDateStr=2026-08-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1787191694245, creator=13701087609, updateTime=1787191694245, updator=13701087609, issue=Issue{id=1297139203754709410, tenantId=1146029695717560320, journalId=1296801528146919473, year='2026', volume='', issue='6', pageStart='3', pageEnd='156', issueExtLink='null', onlineDate='null', pubDate='1782316800000', pubDateStr='2026-06-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1787191685856, creator='13701087609', updateTime=1787192210976, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1297141406343131394, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297139203754709410, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1297141406343131395, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297139203754709410, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=12, endPage=20, ext={EN=ArticleExt(id=1297139239188193861, articleId=1297139238940729924, tenantId=1146029695717560320, journalId=1296801528146919473, language=EN, title=Research Progress on the Molecular Mechanisms and Applications of Nutrient Regulation of Immune Function in Dairy Ruminants, columnId=1297139204610347427, journalTitle=China Dairy, columnName=RUMINANT NUTRITION AND HEALTH, runingTitle=null, highlight=null, articleAbstract=

The immune function of dairy ruminants is a core factor in safeguarding their health status, production performance, and product quality. Nutrients, as the material basis for life activities, also serve as key signaling molecules regulating immune function. Through multiple pathways, such as directly acting on immune cells or indirectly modulating the gastrointestinal microbiota, nutrients profoundly influence the immune function of dairy ruminants. This paper systematically reviewed the direct regulatory mechanisms of key nutrients, such as amino acids and fatty acids, on immune cells, the indirect immune regulatory pathways of nutrients via the gastrointestinal microbiota and their metabolites, the role of nutrients in maintaining the intestinal physical and immune barrier, and the functions of nutrients in alleviating oxidative stress and regulating the balance of inflammatory cytokines. Furthermore, it summarized application strategies for immune enhancement, including the use of functional feed additives, precision nutrition, and phase-feeding. The aim is to provide a theoretical reference for formulating precision nutrition plans, enhancing immunity, and promoting healthy farming practices for dairy ruminants.

, authors=Jianghong LEI¹, Longfei SHI², Qing WANG¹, Yahui QI¹, Min ZHAO¹, authorsList=Jianghong LEI, Longfei SHI, Qing WANG, Yahui QI, Min ZHAO, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1297139239406297670, articleId=1297139238940729924, tenantId=1146029695717560320, journalId=1296801528146919473, language=CN, title=营养素调控乳用反刍动物免疫功能的分子机制与应用研究进展, columnId=1297139204757148069, journalTitle=中国乳业, columnName=反刍动物营养与健康养殖专题, runingTitle=null, highlight=null, articleAbstract=

乳用反刍动物免疫功能是保障其健康状况、生产性能及产品质量的核心要素。营养素作为机体生命活动的物质基础，同时也是调控免疫功能的关键信号分子，通过直接作用于免疫细胞或间接调节胃肠道微生物区系等多条途径，对乳用反刍动物免疫功能产生深远影响。本文系统综述了氨基酸、脂肪酸等关键营养素对免疫细胞的直接调控机制，营养素通过胃肠道微生物区系及代谢产物的间接免疫调控途径，营养素对肠道物理与免疫屏障的维护作用，以及营养素在缓解氧化应激、调节炎症因子平衡中的作用，并总结了功能性饲料添加剂应用、精准营养与阶段饲养等免疫增强应用策略，旨在为乳用反刍动物精准营养方案的制定、免疫力提升及健康养殖提供理论参考。

, authors=雷江红¹, 石龙飞², 王青¹, 齐亚辉¹, 赵敏¹, authorsList=雷江红, 石龙飞, 王青, 齐亚辉, 赵敏, authorCompany=null, correspAuthors=null, authorNote=, correspAuthorsNote=null, copyrightStatement=发表在《中国乳业》上的论文，视为将本论文的数字化复制权、发行权、汇编权及信息网络传播权许可给《中国乳业》使用。本刊已许可中国学术期刊（光盘版）电子杂志社、北京万方数据股份有限公司等多家单位在其相关数据库产品中以数字化方式复制、汇编、发行、信息网络传播本刊全文。作者向本刊提交文章发表的行为即视为同意我刊授权使用该文著作权。, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=vIwJYoPSswT+7YFFKej/Yw==, magXml=lp496yGx8z+IILyAHFyA7A==, pdfUrl=null, pdf=DXsRQ9uTMkvqiHeevV51wA==, pdfFileSize=1895941, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=0ZePfz0bGW7fKLoFbWb1ZQ==, mapNumber=null, fund=null)}, authors=[Author(id=1297139239779590734, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1297139238940729924, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1297139239855088208, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1297139238940729924, authorId=1297139239779590734, language=EN, stringName=Jianghong LEI, firstName=Jianghong, middleName=null, lastName=LEI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Shaanxi Provincial Animal Health and Slaughter Management Station, Xi'an Shaanxi 710016, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1297139239926391377, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1297139238940729924, authorId=1297139239779590734, language=CN, stringName=雷江红, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．陕西省动物卫生与屠宰管理站，陕西 西安 710016, bio={"content":"

雷江红（1973-），男，陕西西安人，本科，高级兽医师，研究方向为动物疫病诊断与防治、兽医公共卫生

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雷江红（1973-），男，陕西西安人，本科，高级兽医师，研究方向为动物疫病诊断与防治、兽医公共卫生

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石龙飞（1988-），男，陕西西安人，硕士，兽医师，研究方向为动物疫病诊断与防治、兽药与生物技术

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石龙飞（1988-），男，陕西西安人，硕士，兽医师，研究方向为动物疫病诊断与防治、兽药与生物技术

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王青（1983-），女，陕西西安人，本科，高级兽医师，研究方向为兽医公共卫生、动物防疫

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王青（1983-），女，陕西西安人，本科，高级兽医师，研究方向为兽医公共卫生、动物防疫

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齐亚辉（1981-），女，陕西西安人，本科，高级兽医师，研究方向为兽医公共卫生、动物防疫

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齐亚辉（1981-），女，陕西西安人，本科，高级兽医师，研究方向为兽医公共卫生、动物防疫

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赵敏（1984-），女，陕西西安人，硕士，高级兽医师，研究方向为动物疫病诊断与防治、兽医公共卫生。

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赵敏（1984-），女，陕西西安人，硕士，高级兽医师，研究方向为动物疫病诊断与防治、兽医公共卫生。

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