Article(id=1297134150536942145, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297134059608630052, articleNumber=null, orderNo=null, doi=10.12377/1671-4393.26.02.12, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1787190481074, onlineDateStr=2026-08-20, pubDate=1771948800000, pubDateStr=2026-02-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1787190481074, onlineIssueDateStr=2026-08-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1787190481074, creator=13701087609, updateTime=1787190481074, updator=13701087609, issue=Issue{id=1297134059608630052, tenantId=1146029695717560320, journalId=1296801528146919473, year='2026', volume='', issue='2', pageStart='2', pageEnd='110', issueExtLink='null', onlineDate='null', pubDate='1771948800000', pubDateStr='2026-02-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1787190459396, creator='13701087609', updateTime=1787192285157, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1297141717472407869, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297134059608630052, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1297141717472407870, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1297134059608630052, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=74, endPage=80, ext={EN=ArticleExt(id=1297134150717297218, articleId=1297134150536942145, tenantId=1146029695717560320, journalId=1296801528146919473, language=EN, title=A Comprehensive Study of Ion Chromatography and Enzymatic Colorimetry in the Determinatiotion of Choline in Infant Formula, columnId=1297134031947194991, journalTitle=China Dairy, columnName=QUALITY CONTROL, runingTitle=null, highlight=null, articleAbstract=
[Objective]

Compare and evaluate the application of ion chromatography and enzymatic colorimetry in the determination of choline in infant formula milk powder, and select a more suitable detection method for enterprise quality control.

[Method]

A comparative analysis between ion chromatography and enzymatic colorimetry was conducted by using indicators such as standard curves, detection limits, precision, accuracy, uncertainty assessment and determination costs.

[Result]

Both ion chromatography and enzymatic colorimetry demonstrated good linear relationships within their respective concentration ranges, with correlation coefficients (R2) of 0.999 7 and 0.999 1, respectively. The detection limits and quantification limits of ion chromatography were 0.7 mg/100 g and 2.1 mg/100 g, while those of enzymatic colorimetry were 0.9 mg/100 g and 2.7 mg/100 g. The recovery rates of ion chromatography and enzymatic colorimetry ranged were 90.7%~102.7% and 86.0%~100.6% (with the spiked amount ranging from 3 mg/100 g to 150 mg/100 g), respectively. The precision of ion chromatography (0.61%~3.83%) was superior to that of enzymatic colorimetry (1.30%~5.85%). The expanded uncertainties for ion chromatography and enzymatic colorimetry were 4.02% and 4.04%, respectively.

[Conclusion]

Ion chromatography demonstrated comparable advantages over enzymatic colorimetry in terms of sensitivity, precision and cost. It is more suitable for both qualitative and quantitative analysis of choline in infant formula and is recommended as the primary method for enterprises determination.

, authors=Xing GAO1, Dan ZHAO2, Hao ZHANG2, Jindi TU1, Weijing YANG2, Bin LIANG2, Li ZHANG1, Guofeng HOU1, *, authorsList=Xing GAO, Dan ZHAO, Hao ZHANG, Jindi TU, Weijing YANG, Bin LIANG, Li ZHANG, Guofeng HOU, authorCompany=null, correspAuthors=Guofeng HOU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1297134150939595331, articleId=1297134150536942145, tenantId=1146029695717560320, journalId=1296801528146919473, language=CN, title=离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的对比研究, columnId=1297134032135938673, journalTitle=中国乳业, columnName=质量安全, runingTitle=null, highlight=null, articleAbstract=
[目的]

对比评估离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的应用,选择一种更适用于企业质量控制的检测方法。

[方法]

通过对比标准曲线、检出限、精密度、准确度、不确定度评定及检测成本等指标,对离子色谱法和酶比色法进行分析。

[结果]

离子色谱法和酶比色法在各自的浓度范围内均表现出良好的线性关系,相关系数(R2)分别为0.999 7和0.999 1;离子色谱法的检出限和定量限分别为0.7 mg/100 g和2.1 mg/100 g,酶比色法的检出限和定量限分别为0.9 mg/100 g和2.7 mg/100 g;离子色谱法和酶比色法的回收率范围分别为90.7%~102.7%和86.0%~100.6%(加标量在3 mg/100 g~150 mg/100 g时);离子色谱法的精密度(0.61%~3.83%)优于酶比色法(1.30%~5.85%);离子色谱法和酶比色法的扩展不确定度分别为4.02%和4.04%。

[结论]

离子色谱法在灵敏度、精密度和检测成本方面均优于酶比色法,更适用于婴幼儿配方乳粉中胆碱的定性和定量分析,建议作为企业检测的首选方法。

, authors=高星1, 赵丹2, 张浩2, 屠锦娣1, 杨维静2, 梁斌2, 张莉1, 候国峰1, *, authorsList=高星, 赵丹, 张浩, 屠锦娣, 杨维静, 梁斌, 张莉, 候国峰, authorCompany=null, correspAuthors=候国峰, authorNote=

高星(1990-),女,甘肃白银人,硕士,工程师,研究方向为食品检测

赵丹(1992-),男,陕西宝鸡人,本科,工程师,研究方向为乳制品检测

张浩(1991-),男,陕西渭南人,本科,助理工程师,研究方向为食品检测

屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

杨维静(1991-),女,陕西渭南人,本科,工程师,研究方向为乳制品生产质量安全

梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

, correspAuthorsNote=

*

候国峰(1988-),男,山西临汾人,硕士,高级工程师,研究方向为食品检测。
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高星(1990-),女,甘肃白银人,硕士,工程师,研究方向为食品检测

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张浩(1991-),男,陕西渭南人,本科,助理工程师,研究方向为食品检测

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张浩(1991-),男,陕西渭南人,本科,助理工程师,研究方向为食品检测

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屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

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屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

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杨维静(1991-),女,陕西渭南人,本科,工程师,研究方向为乳制品生产质量安全

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梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

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梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

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张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

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张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

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离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的对比研究
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高星 1 , 赵丹 2 , 张浩 2 , 屠锦娣 1 , 杨维静 2 , 梁斌 2 , 张莉 1 , 候国峰 1, *
中国乳业 | 质量安全 2026,(2): 74-80
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中国乳业 |质量安全 2026 , (2) : 74 -80
离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的对比研究
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高星(1990-),女,甘肃白银人,硕士,工程师,研究方向为食品检测

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赵丹(1992-),男,陕西宝鸡人,本科,工程师,研究方向为乳制品检测

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张浩(1991-),男,陕西渭南人,本科,助理工程师,研究方向为食品检测

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屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

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屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

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杨维静(1991-),女,陕西渭南人,本科,工程师,研究方向为乳制品生产质量安全

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杨维静(1991-),女,陕西渭南人,本科,工程师,研究方向为乳制品生产质量安全

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梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

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梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

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张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

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张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

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高星1, 赵丹2, 张浩2, 屠锦娣1, 杨维静2, 梁斌2, 张莉1, 候国峰1, *
作者信息
  • 1.陕西科仪阳光检测技术服务有限公司,陕西 西安 710000
  • 2.陕西圣唐乳业有限公司,陕西 渭南 711700
通讯作者:

*

候国峰(1988-),男,山西临汾人,硕士,高级工程师,研究方向为食品检测。
作者简介:

高星(1990-),女,甘肃白银人,硕士,工程师,研究方向为食品检测

赵丹(1992-),男,陕西宝鸡人,本科,工程师,研究方向为乳制品检测

张浩(1991-),男,陕西渭南人,本科,助理工程师,研究方向为食品检测

屠锦娣(1977-),女,陕西咸阳人,本科,高级工程师,研究方向为食品、环境检测

杨维静(1991-),女,陕西渭南人,本科,工程师,研究方向为乳制品生产质量安全

梁斌(1990-),男,陕西咸阳人,硕士,工程师,研究方向为婴幼儿配方羊奶粉生产工艺

张莉(1957-),女,陕西西安人,本科,高级工程师,研究方向为食品、环境检测。

A Comprehensive Study of Ion Chromatography and Enzymatic Colorimetry in the Determinatiotion of Choline in Infant Formula
Xing GAO1, Dan ZHAO2, Hao ZHANG2, Jindi TU1, Weijing YANG2, Bin LIANG2, Li ZHANG1, Guofeng HOU1, *
Affiliations
  • 1.Shaanxi Keyi Sunshine Test Services Co., Ltd., Xi'an Shanxi 710000
  • 2.Shaanxi Shengtang Dairy Co., Ltd., Weinan Shaanxi 711700
出版时间: 2026-02-25 doi: 10.12377/1671-4393.26.02.12
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[目的]

对比评估离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的应用,选择一种更适用于企业质量控制的检测方法。

[方法]

通过对比标准曲线、检出限、精密度、准确度、不确定度评定及检测成本等指标,对离子色谱法和酶比色法进行分析。

[结果]

离子色谱法和酶比色法在各自的浓度范围内均表现出良好的线性关系,相关系数(R2)分别为0.999 7和0.999 1;离子色谱法的检出限和定量限分别为0.7 mg/100 g和2.1 mg/100 g,酶比色法的检出限和定量限分别为0.9 mg/100 g和2.7 mg/100 g;离子色谱法和酶比色法的回收率范围分别为90.7%~102.7%和86.0%~100.6%(加标量在3 mg/100 g~150 mg/100 g时);离子色谱法的精密度(0.61%~3.83%)优于酶比色法(1.30%~5.85%);离子色谱法和酶比色法的扩展不确定度分别为4.02%和4.04%。

[结论]

离子色谱法在灵敏度、精密度和检测成本方面均优于酶比色法,更适用于婴幼儿配方乳粉中胆碱的定性和定量分析,建议作为企业检测的首选方法。

食品检验  /  胆碱  /  离子色谱法  /  酶比色法  /  婴幼儿配方乳粉
[Objective]

Compare and evaluate the application of ion chromatography and enzymatic colorimetry in the determination of choline in infant formula milk powder, and select a more suitable detection method for enterprise quality control.

[Method]

A comparative analysis between ion chromatography and enzymatic colorimetry was conducted by using indicators such as standard curves, detection limits, precision, accuracy, uncertainty assessment and determination costs.

[Result]

Both ion chromatography and enzymatic colorimetry demonstrated good linear relationships within their respective concentration ranges, with correlation coefficients (R2) of 0.999 7 and 0.999 1, respectively. The detection limits and quantification limits of ion chromatography were 0.7 mg/100 g and 2.1 mg/100 g, while those of enzymatic colorimetry were 0.9 mg/100 g and 2.7 mg/100 g. The recovery rates of ion chromatography and enzymatic colorimetry ranged were 90.7%~102.7% and 86.0%~100.6% (with the spiked amount ranging from 3 mg/100 g to 150 mg/100 g), respectively. The precision of ion chromatography (0.61%~3.83%) was superior to that of enzymatic colorimetry (1.30%~5.85%). The expanded uncertainties for ion chromatography and enzymatic colorimetry were 4.02% and 4.04%, respectively.

[Conclusion]

Ion chromatography demonstrated comparable advantages over enzymatic colorimetry in terms of sensitivity, precision and cost. It is more suitable for both qualitative and quantitative analysis of choline in infant formula and is recommended as the primary method for enterprises determination.

food testing  /  choline  /  ion chromatography  /  enzymatic colorimetry  /  infant formula
高星, 赵丹, 张浩, 屠锦娣, 杨维静, 梁斌, 张莉, 候国峰. 离子色谱法与酶比色法在婴幼儿配方乳粉胆碱检测中的对比研究. 中国乳业, 2026 , (2) : 74 -80 . DOI: 10.12377/1671-4393.26.02.12
Xing GAO, Dan ZHAO, Hao ZHANG, Jindi TU, Weijing YANG, Bin LIANG, Li ZHANG, Guofeng HOU. A Comprehensive Study of Ion Chromatography and Enzymatic Colorimetry in the Determinatiotion of Choline in Infant Formula[J]. China Dairy, 2026 , (2) : 74 -80 . DOI: 10.12377/1671-4393.26.02.12
  • 渭南市重点研发计划项目-免疫功能性羊乳产品研发与示范(2024ZDYFJH-790)
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2026年第卷第2期
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doi: 10.12377/1671-4393.26.02.12
  • 首发时间:2026-08-20
  • 出版时间:2026-02-25
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渭南市重点研发计划项目-免疫功能性羊乳产品研发与示范(2024ZDYFJH-790)
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    1.陕西科仪阳光检测技术服务有限公司,陕西 西安 710000
    2.陕西圣唐乳业有限公司,陕西 渭南 711700

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候国峰(1988-),男,山西临汾人,硕士,高级工程师,研究方向为食品检测。
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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