Article(id=1319995136252170324, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1319995133400035493, articleNumber=null, orderNo=null, doi=10.12377/1671-4393.25.09.12, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792640964806, onlineDateStr=2026-10-22, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792640964806, onlineIssueDateStr=2026-10-22, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792640964806, creator=13701087609, updateTime=1792640964806, updator=13701087609, issue=Issue{id=1319995133400035493, tenantId=1146029695717560320, journalId=1296801528146919473, year='2025', volume='', issue='9', pageStart='1', pageEnd='156', issueExtLink='null', onlineDate='null', pubDate='1758729600000', pubDateStr='2025-09-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792640964126, creator='13701087609', updateTime=1792641131282, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319995834578620801, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1319995133400035493, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319995834578620802, tenantId=1146029695717560320, journalId=1296801528146919473, issueId=1319995133400035493, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=78, endPage=83, ext={EN=ArticleExt(id=1319995138533871702, articleId=1319995136252170324, tenantId=1146029695717560320, journalId=1296801528146919473, language=EN, title=Impacts of Heat Stress on Production Performance,Milk Quality,and Blood Biochemical Indicators of Dairy Cows in Different Lactation Stages in Linyi Region, columnId=1297134029740995352, journalTitle=China Dairy, columnName=FEEDING MANAGEMENT, runingTitle=null, highlight=null, articleAbstract=[Objective] This study aimed to investigate the effects of heat stress on production performance, milk composition,and blood biochemical indicators of dairy cows in different lactation stages in the Linyi region. [Methods] A total of 24 healthy Holstein cows were selected and divided into three groups according to days in milk: early lactation （≤60 d）, mid-lactation （61~150 d）,and late lactation （≥151 d）. The experiment was conducted from May to August 2024. Milk yield,respiratory rate,rectal temperature,milk composition,and blood indicators （HSP70,prolactin,leptin） were monitored during non-heat stress and heat stress periods. [Results] Heat stress significantly reduced milk yield in all lactation stages （P< 0.05） and significantly increased respiratory rate and rectal temperature. The lactose and solid content increased significantly in early and mid-lactation cows （P< 0.05）,while milk fat rate and milk protein rate showed no significant changes. Heat stress also significantly up-regulated HSP70 expression and reduced prolactin levels in early and mid-lactation cows （P< 0.05）,with no significant change in leptin levels. [Conclusion] Heat stress significantly affects the production performance,milk quality,and blood indicators of dairy cows,with early and mid-lactation cows being more susceptible. The results provide a theoretical basis for developing regional strategies for the prevention and control of heat stress in dairy cows., authors=ZHAO Jianfa, authorsList=ZHAO Jianfa, authorCompany=Livestock Development Promotion Center of Hedong District,Linyi Shandong 276032, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319995138445791317, articleId=1319995136252170324, tenantId=1146029695717560320, journalId=1296801528146919473, language=CN, title=临沂地区热应激对不同泌乳期奶牛生产性能、乳品质及血液生化指标的影响, columnId=1297134031582294810, journalTitle=中国乳业, columnName=饲养管理, runingTitle=null, highlight=null, articleAbstract=[目的]探究热应激条件下临沂地区不同泌乳阶段奶牛的生产性能、乳成分及血液生化指标的变化特征。[方法]选取24 头健康荷斯坦牛,按泌乳天数分为早期（≤60 d）、中期（61~150 d）和晚期（≥151 d）三组,于2024年5—8月进行试验,监测非热应激期与热应激期奶牛的产奶量、呼吸频率、直肠温度、乳成分及血液指标（HSP70、催乳素、瘦素）。[结果]热应激显著降低各泌乳阶段奶牛的产奶量（P<0.05）,并导致呼吸频率和直肠温度显著升高。泌乳早期和中期奶牛的乳糖与固形物含量显著增加（P<0.05）,而乳脂肪率和乳蛋白率无显著变化。热应激还显著上调HSP70表达,并降低泌乳早期和中期奶牛的催乳素水平（P<0.05）,瘦素水平变化不显著。[结论]热应激对奶牛生产性能、乳品质和血液指标均有显著影响,泌乳早期和中期奶牛更为敏感。研究结果为制定区域性奶牛热应激防控策略提供了理论依据。, authors=赵建发, authorsList=赵建发, authorCompany=临沂市河东区畜牧发展促进中心,山东临沂 276032, correspAuthors=null, authorNote=赵建发（1986-）,男,山东临沂人,本科,高级兽医师,研究方向为畜牧兽医技术。, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=w35WwAXVkAJAdDoOO65jDA==, pdfFileSize=1296346, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1319995138684866647, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=1, keyword=热应激), Keyword(id=1319995138747781208, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=2, keyword=泌乳阶段), Keyword(id=1319995138810695769, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=3, keyword=产奶量), Keyword(id=1319995138886193242, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=4, keyword=乳成分), Keyword(id=1319995138957496411, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=5, keyword=血液指标), Keyword(id=1319995139049771100, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=CN, orderNo=6, keyword=临沂地区), Keyword(id=1319995139175600221, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=1, keyword=heat stress), Keyword(id=1319995139246903390, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=2, keyword=lactation stage), Keyword(id=1319995139322400863, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=3, keyword=milk yield), Keyword(id=1319995139389509728, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=4, keyword=milk composition), Keyword(id=1319995139465007201, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=5, keyword=blood indicators), Keyword(id=1319995139544698978, tenantId=1146029695717560320, journalId=1296801528146919473, articleId=1319995136252170324, language=EN, orderNo=6, keyword=Linyi region)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1296801172792901679, delFlag=0, nameCn=中国乳业, nameEn=China Dairy, nameHistory1=null, nameHistory2=null, issn=1671-4393, eissn=null, cn=11-4768/S, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=fy0U6rTUhrcBdKszdYVe3w==, journalPrice=null, startedYear=null, abbrevIsoEn=China Dairy, journalRemark=null, publicationField=null, createdTime=1787111092997, updatedTime=1788949480572, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Agriculture, subjectName=null, subjectCodeEn=Agriculture, subjectNameEn=null, picCn=fy0U6rTUhrcBdKszdYVe3w==, picEn=1lm7RNSd456gWkkoaDGdEQ==, jcr=null, cjcr=null, exts=[JournalExt(id=1304511929255481461, language=CN, name=中国乳业, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949480594, updatedTime=1788949480594, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zgryauthor.cast.org.cn/webm, submissionEditorUrl=https://zgryeditor.cast.org.cn/webm, submissionReviewUrl=https://zgryauthor.cast.org.cn/webm, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304511929301618806, language=EN, name=China Dairy, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949480605, updatedTime=1788949480605, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zgryauthor.cast.org.cn/webm, submissionEditorUrl=https://zgryeditor.cast.org.cn/webm, submissionReviewUrl=https://zgryauthor.cast.org.cn/webm, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1296801528146919473, websiteList=[Website(id=1296802542923572121, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1296801528146919473, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgry/CN, language=CN, createTime=1787111419659, createBy=18614031015, updateTime=1787111471367, updateBy=18614031015, name=中国乳业-中文, tplId=1146099689490845704, title=中国乳业, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1296802881777198042, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=articleTextType, value=kx, createTime=1787111500448, updateTime=1787111500448, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881747837911, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=banner, value=null, createTime=1787111500441, updateTime=1787111500441, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881827529693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=grayFlag, value=0, createTime=1787111500460, updateTime=1787111500460, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881735254998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=logo, value=https://castjournals.cast.org.cn/joweb/zgry/CN/file/pic?fileId=qVbzVKBQlSo4CZ2uDrqTZw==, createTime=1787111500438, updateTime=1787111500438, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881844306911, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=minRunFlag, value=0, createTime=1787111500464, updateTime=1787111500464, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881768809433, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgry/CN/file/pic, createTime=1787111500446, updateTime=1787111500446, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881835918302, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=silenceFlag, value=0, createTime=1787111500462, updateTime=1787111500462, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881760420824, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1787111500444, updateTime=1787111500444, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881810752475, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=themeColor, value=null, createTime=1787111500456, updateTime=1787111500456, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802881819141084, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802542923572121, code=themeStyle, value=null, createTime=1787111500458, updateTime=1787111500458, creator=18614031015, updator=18614031015)]), Website(id=1296802543032624028, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1296801528146919473, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgry/EN, language=EN, createTime=1787111419685, createBy=18614031015, updateTime=1787111462939, updateBy=18614031015, name=中国乳业-英文, tplId=1146101810881728533, title=China Dairy, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1296802850798068681, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=articleTextType, value=kx, createTime=1787111493062, updateTime=1787111493062, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850768708550, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=banner, value=null, createTime=1787111493055, updateTime=1787111493055, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850819040204, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=grayFlag, value=0, createTime=1787111493067, updateTime=1787111493067, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850760319941, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=logo, value=https://castjournals.cast.org.cn/joweb/zgry/EN/file/pic?fileId=qVbzVKBQlSo4CZ2uDrqTZw==, createTime=1787111493053, updateTime=1787111493053, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850831623118, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=minRunFlag, value=0, createTime=1787111493070, updateTime=1787111493070, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850789680072, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgry/EN/file/pic, createTime=1787111493060, updateTime=1787111493060, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850823234509, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=silenceFlag, value=0, createTime=1787111493068, updateTime=1787111493068, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850781291463, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1787111493058, updateTime=1787111493058, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850802262986, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=themeColor, value=null, createTime=1787111493063, updateTime=1787111493063, creator=18614031015, updator=18614031015), WebsiteProps(id=1296802850810651595, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1296802543032624028, code=themeStyle, value=null, createTime=1787111493065, updateTime=1787111493065, creator=18614031015, updator=18614031015)])], journalTitle=中国乳业, weixinUrl=null, journalUrl=http://zhgry.aiijournal.com/, iacademicId=null, status=1, seqNo=null, journalTitleEn=China Dairy, journalPhotoCn=fy0U6rTUhrcBdKszdYVe3w==, journalPhotoEn=1lm7RNSd456gWkkoaDGdEQ==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zgry/CN/10.12377/1671-4393.25.09.12, detailUrlEn=https://castjournals.cast.org.cn/joweb/zgry/EN/10.12377/1671-4393.25.09.12, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zgry/CN/PDF/10.12377/1671-4393.25.09.12, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zgry/EN/PDF/10.12377/1671-4393.25.09.12, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1792640964806, fullTextJson=null, articleText=null, reference=[1] 郭咏梅,李佳荣,闫素梅,等.热应激对奶牛的危害及营养调控措施[J].饲料研究,2023,46(14):174-179.
[2] 刘淑荣. 奶牛热应激的预防[J].今日畜牧兽医,2024,40(12):45-47.
[3] 周进,李艳,吴佳颖,等.不同温湿指数下奶牛体温、脉搏和呼吸频率的变化规律研究[J].黑龙江畜牧兽医,2024(12):50-53.
[4] 郑洁怡,杨舒黎,赵开玲,等.热应激对反刍动物瘤胃功能及潜在耐热标志物的影响[J].中国畜牧兽医,2024,51(3):1041-1049.
[5] 王海利,顾鲲涛.热应激对奶牛产奶性能和泌乳相关激素影响[J].中兽医学杂志,2019(5):97-99.
[6] 赵加军. 临沂市奶牛主要寄生虫病的流行现状与对策[J].中国乳业,2024(3):39-45.
[7] 杜肖肖,邓铭,孙宝丽,等.奶牛热应激调控措施研究进展[J].中国奶牛,2024(5):1-7.
[8] 张志登,敬盈嘉,刘影,等.热应激对泌乳奶牛生理指标及生产性能的影响[J].中国畜牧杂志,2020,56(4):169-172.
[9] 张凡建,徐聪,翁晓刚,等.不同程度热应激对泌乳中期奶牛产奶量和乳成分的影响[J].中国兽医学报,2014,34(10):1686-1688.
[10] Tao S,Rivas R M O,Marins T N,et al.Impact of heat stress on lactational performance of dairy cows[J].Theriogenology,2020,150:437-444.
[11] Tao S,Bubolz J W,Do Amaral B C,et al.Effect of heat stress during the dry period on mammary gland development[J].Journal of Dairy Science,2011,94(12):5976-5986.
[12] 彭丹丹. 温热环境和个体热敏感性对奶牛产奶性能及生理应激指标的影响[D].北京:中国农业科学院,2018.
[13] Soriani N,Panella G,Calamari L.Rumination time during the summer season and its relationships with metabolic conditions and milk production[J].Journal of Dairy Science ,2013, 96(8):5082-5094.
[14] El-tarabany M S,El-tarabany A A.Impact of maternal heat stress at insemination on the subsequent reproductive performance of Holstein Brown Swis,and their crosses[J].Theriogenology,2015,(84)9:1523-1529.
[15] 陈强,李忠浩,王根林.奶牛HSP70基因多态性与生产性能的关系[J].江西农业学报,2007,19(7):84-86.
[16] 宋代军,何钦,姚焰础.热应激对不同泌乳阶段奶牛生产性能和血清激素浓度的影响[J].动物营养学报,2013,25(10):2294-2302.
[17] 牛淑玲,李艳飞,王哲,等.围产期健康奶牛干物质摄入水平与血浆瘦素浓度及乳产量的关系[J].中国畜牧杂志,2005,41(3):17-20.)