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[Method] A total of 60 late lactating Holstein cows with similar body weight,parity,lactation period, and milk yield were selected and randomly divided into 4 groups：Control group,Experiment I Experiment II and Experiment III,with 15 cows per group. The control group was fed conventional feed,while Experiment I,II and III groups were supplemented with 100 g/d,200 g/d,and 300 g/d herbal additives,respectively,on the basis of conventional feed. The entire experimental period lasted for 9 weeks. [Result] From the second week,the milk yield in the experimental groups significantly increased （p<0.05）. The milk quality indicators （milk fat rate,lactose rate, and milk protein rate）, serum biochemical indicators （albumin and globulin）,and immune indicators （IgM, IgG, and IL-2） in Experiment II and III groups were significantly higher than those in the control group （p<0.05）. [Conclusion] Herbal feed additives significantly improved the milk yield and milk composition of late lactating dairy cows,enhanced metabolic levels,and boosted immune function,with the optimal effect at 200 g/d. These findings provide a reference for improving dairy cow production efficiency., authors=YI Wenjuan, authorsList=YI Wenjuan, authorCompany=Animal Disease Prevention and Control Center,Qixia Shandong 265300, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319613287768117550, articleId=1319613287449350445, tenantId=1146029695717560320, journalId=1296801528146919473, language=CN, title=中草药饲料添加剂对奶牛泌乳后期泌乳性能、血清生化和免疫功能的影响, columnId=1297134031582294810, journalTitle=中国乳业, columnName=饲养管理, runingTitle=null, highlight=null, articleAbstract=[目的] 研究不同剂量中草药添加剂对奶牛泌乳后期的泌乳性能、乳品质量、血清生化指标和免疫功能的影响。[方法] 选取60 头体重、胎次、泌乳期、泌乳量相近的泌乳后期荷斯坦牛,将奶牛随机分成 4 组：对照组、试验Ⅰ组、试验Ⅱ组、试验Ⅲ组,每组 15 头。对照组饲喂常规饲料,试验Ⅰ组、试验Ⅱ组和试验Ⅲ组在常规饲料基础上添加100 g/d、200 g/d、300 g/d中草药添加剂。整个试验周期为9 周。[结果] 从第2周开始,试验组产奶量显著增加（p<0.05）。试验Ⅱ组、试验Ⅲ组乳品质指标（乳脂率、乳糖率、乳蛋白率）、血清生化指标（白蛋白、球蛋白）、免疫指标（IgM、IgG、IL-2）显著高于对照组（p<0.05）。[结论] 中草药添加剂可明显提高泌乳后期奶牛产奶量和乳品成分,改善代谢水平,增强免疫功能,200 g/d的效果最佳。这些研究结果为提高奶牛生产效益提供了参考依据。, authors=衣文娟, authorsList=衣文娟, authorCompany=山东省栖霞市动物疫病预防控制中心,山东栖霞 265300, correspAuthors=null, authorNote=衣文娟（1973- ）,女,山东栖霞人,本科,高级兽医师,研究方向为畜牧兽医。, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, 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[2] 赵明山. 中草药饲料添加剂对奶牛产奶量及牛奶品质的影响[J]. 今日畜牧兽医,2024,40(1):71-73.
[3] 公啸,王悦尚.中草药添加剂的生物学功能及其在反刍动物生产和疾病防治中的应用[J]. 饲料研究,2024,47(10):171-175.
[4] 杨爱荣. 中草药添加剂对荷斯坦奶牛生产性能的影响[J]. 中国畜禽种业,2023,19(4):75-78.
[5] 欧阳富龙,彭媛媛,蔡懿鑫,等.复方中草药添加剂对围产期奶牛干物质采食量、生产性能及生殖激素的影响[J]. 中国饲料,2017(3):27-32.
[6] 牛章杰,许雪玲,苏立群,等.黄芪通乳汤辨证加减治疗缺乳[J]. 光明中医,2011,26(4):2.
[7] 霍萍丽,马金波.复方中草药对奶牛泌乳性能、乳品质和血清生化指标的影响[J]. 饲料研究,2022(10):45.
[8] 汪悦,王炳,苏汉书,等.牛奶体细胞生成与乳品质量和安全的关系[J]. 动物营养学报,2017,29(7):9.
[9] 郑国军,罗天瑶,王刚,等.发酵黄芪对奶牛泌乳及体细胞的影响[J]. 现代畜牧科技,2020(5):5-7.
[10] 李自鸿,刘衡,陈佳洁,等.五种滇西中草药的总黄酮含量测定及抗菌、抗氧化活性初步研究[J]. 广州化工,2023(21):051.
[11] 毛桂芸,张永飞,郭延生,等.山楂对围产期奶牛肝功能和血脂的影响[J]. 中国奶牛,2020(8):4.
[12] 张磊,冯士彬,王希春,等.乳房炎奶牛部分血液生化指标的变化[J]. 畜牧与饲料科学,2009,30(3):163-164.
[13] 张春刚. 乳中IgA和IgM含量的变化及其影响因素的机理研究[D]. 扬州大学,2008.
[14] Zhang Q,Hresko M E,Picton L K,et al.A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia[J]. Science Translational Medicine,2021,13(625):eabg6986.
[15] 杨志操. 中草药对奶牛生产性能和血清免疫指标的影响[J]. 现代畜牧科技,2023(5):50-52.
[16] 赵贵宝. 复方中草药对奶牛产后瘫痪症的临床疗效试验[J]. 中国乳业,2024(10):44-49.)