Article(id=1314918555833958877, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918450573701162, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1748275200000, receivedDateStr=2025-05-27, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791430613716, onlineDateStr=2026-10-08, pubDate=1766160000000, pubDateStr=2025-12-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791430613716, onlineIssueDateStr=2026-10-08, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791430613716, creator=13701087609, updateTime=1791430613716, updator=13701087609, issue=Issue{id=1314918450573701162, tenantId=1146029695717560320, journalId=1234093305789726721, year='2025', volume='45', issue='12', pageStart='6513', pageEnd='7104', issueExtLink='null', onlineDate='null', pubDate='1766160000000', pubDateStr='2025-12-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791430588620, creator='13701087609', updateTime=1791431575400, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1314922589479333965, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918450573701162, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1314922589479333966, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918450573701162, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=6996, endPage=7007, ext={EN=ArticleExt(id=1314918556031091166, articleId=1314918555833958877, tenantId=1146029695717560320, journalId=1234093305789726721, language=EN, title=Exposure characteristics and associations of per- and polyfluoroalkyl substances in paired blood and hair samples, columnId=1234106388687934088, journalTitle=China Environmental Science, columnName=Environmental Toxicology and Environmental Health, runingTitle=null, highlight=null, articleAbstract=

Per- and polyfluoroalkyl substances (PFAS) are typical emerging contaminants with persistence, bioaccumulation, and toxicity (PBT) properties. Female e-waste dismantling workers are at heightened risk because of their occupational activities. To characterize exposure patterns and explore the potential of hair as a non-invasive biomarker, we longitudinally evaluated 24 female workers via two sampling rounds separated by three months. Serum and hair samples were analyzed for PFAS concentrations, compositional profiles, and inter-matrix correlations. Twenty-seven PFAS were quantified in serum (median total concentration: 108ng/mL; range: 42.8~228ng/mL), while thirteen PFAS were detected in hair (median total concentration: 6.53ng/g; range: 2.92~37.1ng/g). Perfluorooctanoic acid (PFOA) dominated both matrices, accounting for 47.0% of total PFAS in serum and 39.5% in hair. Positively dose-dependent relationships were observed between contemporaneous serum and hair concentrations for PFOA, perfluorononanoic acid (PFNA), perfluoroundecanoic acid (PFUdA), perfluorooctane sulfonic acid (PFOS), and 6:2 chlorinated polyfluoroalkyl ether sulfonate (6:2Cl-PFESA). When serum levels increased from the 10th to the 75th percentile, corresponding hair concentrations rose by 299.88%, 522.14%, 166.98%, 276.97% and 323.34%, respectively. In contrast, no significant associations were found between current hair PFAS levels and serum levels measured three months earlier. Employment duration and workplace type did not significantly influence PFAS burdens. These results validate hair as a practical, non-invasive matrix for PFAS exposure assessment and provide critical evidence for environmental health risk evaluation in this high-exposure occupational group.

, authors=Li LI^{1, 2}, Zu-lan ZHAO^{1, 2}, Lu-lu HUANG^{1, 2}, Xue CAO^{2, 3}, Rui-xin QIN^{2, 4, 5}, Shi-yi ZHANG^{2, 4, 5}, Chun XIE¹, Qi-long LIAO², Jing ZHENG^{1, 2, *}, authorsList=Li LI, Zu-lan ZHAO, Lu-lu HUANG, Xue CAO, Rui-xin QIN, Shi-yi ZHANG, Chun XIE, Qi-long LIAO, Jing ZHENG, authorCompany=null, correspAuthors=Jing ZHENG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1314918556404384223, articleId=1314918555833958877, tenantId=1146029695717560320, journalId=1234093305789726721, language=CN, title=血液与头发中PFAS暴露特征及关联性研究, columnId=1234106394006311784, journalTitle=中国环境科学, columnName=环境毒理与健康, runingTitle=null, highlight=null, articleAbstract=

本文以24名电子垃圾拆解女工为研究对象，通过间隔3个月的两次血液和头发配对采样，分析了血液和头发中PFAS的浓度水平、组成特征及关联性，并评估了该职业人群的暴露特征及头发作为非侵入性生物标志物的可行性．结果显示，女工血清中共检测到 27种PFAS，总浓度范围为42.8~228ng/mL，中值为108ng/mL；头发中共检测到13种PFAS，总浓度范围为2.92~37.1ng/g，中值为6.53ng/g；全氟辛酸（PFOA）是血清与头发中含量最高的PFAS，占比分别为47.0%和39.5%．在同一采样时间节点，配对血清与头发样本中PFOA、全氟壬酸（PFNA）、全氟十一酸（PFUdA）、全氟辛烷磺酸（PFOS）、6：2氯代全氟醚磺酸（6：2Cl-PFESA）呈剂量依赖性相关，当上述PFAS血清浓度分别处于第75百分位数时，与血清浓度处于第10百分位数相比，头发中浓度分别上升299.88%、522.14%、166.98%、276.97%和323.34%个标准差，暂未观察到头发中PFAS浓度与采样节点前3个月血清PFAS浓度之间的关联．Spearman和Mann-Whitney U分析表明工作年限和工作场所对PFAS浓度无显著影响．本研究揭示了头发在表征PFAS人体内负荷的价值，为PFAS环境暴露风险评估和非侵入性监测方法的开发提供了科学依据．

, authors=李丽^{1, 2}, 赵祖兰^{1, 2}, 黄璐璐^{1, 2}, 曹雪^{2, 3}, 秦瑞欣^{2, 4, 5}, 张释义^{2, 4, 5}, 谢春¹, 廖其龙², 郑晶^{1, 2, *}, authorsList=李丽, 赵祖兰, 黄璐璐, 曹雪, 秦瑞欣, 张释义, 谢春, 廖其龙, 郑晶, authorCompany=null, correspAuthors=郑晶, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=fJTf0b1KrY37PH8wE83rPw==, magXml=XOTqYkdocQTMYTJovU7mkw==, pdfUrl=null, pdf=Ll0lDKuO2NtXcWT1y8slGg==, pdfFileSize=2136237, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=DuYl4JSrqAdXIKIEjAXPRg==, mapNumber=null, fund=null)}, authors=[Author(id=1314918557062889968, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918555833958877, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=1347016269@qq.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1314918557163553267, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918555833958877, authorId=1314918557062889968, language=EN, stringName=Li LI, firstName=Li, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=^1.Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 561113, China
^2.The Key Laboratory of Environmental Pollution Health Risk Assessment, Ministry of Ecology and Environment of the People's Republic of China, Research Center of Emerging Contaminants, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1314918557243245044, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918555833958877, authorId=1314918557062889968, language=CN, stringName=李丽, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=^1.贵州医科大学公共卫生与健康学院，环境污染与疾病监控教育部重点实验室，贵州 贵阳 561113
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李丽（1999-），女，贵州遵义人，贵州医科大学硕士研究生，研究方向为环境与健康．发表论文5篇．1347016269@qq.com.

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李丽（1999-），女，贵州遵义人，贵州医科大学硕士研究生，研究方向为环境与健康．发表论文5篇．1347016269@qq.com.

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