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Both unsuitable temperatures and air pollution increase the health risks of chronic obstructive pulmonary disease (COPD). To evaluate the single-effect effects of temperature, PM_2.5 and O₃, as well as the the interaction effects of temperature and PM_2.5 (or O₃) and the interaction effects of PM_2.5 and O₃, COPD hospital admissions among residents in Tianjin from 2014 to 2019 were collected for quantitative analysis using the generalized additive model. The results indicated that temperature significantly influenced COPD hospitalizations in Tianjin, with the low-temperature effect markedly stronger than the high-temperature effect. Low temperatures exerted a greater impact on females and the elderly. At maximum lag effects, every 10μg/m³ increase in PM_2.5 and O₃ concentrations was associated with 1.23% (95% CI: 0.79%, 1.67%) and 0.90% (95% CI: 0.58%, 1.23%) rise in COPD hospitalization risk, respectively. Interaction analysis revealed synergistic effects between low temperatures and high PM_2.5 levels, as well as between high temperatures and elevated O₃ concentrations.Moreover, at high temperatures, as the concentration of PM₂.5 increases, the risk of hospitalization for COPD caused by O₃ exposure will increase. Given the increasing frequency of extreme weather events, greater attention should be directed to the combined health risks of non-optimal temperatures and air pollution for COPD. Measures such as early warning systems and preemptive interventions are recommended.

, authors=Xiao-jia WANG, Jing DING, Qing YAO^*, Su-qin HAN, authorsList=Xiao-jia WANG, Jing DING, Qing YAO, Su-qin HAN, authorCompany=null, correspAuthors=Qing YAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1314918548544258434, articleId=1314918548091273600, tenantId=1146029695717560320, journalId=1234093305789726721, language=CN, title=气温与PM_2.5、O₃交互作用对天津市慢性阻塞性肺疾病住院人数的影响, columnId=1234106394006311784, journalTitle=中国环境科学, columnName=环境毒理与健康, runingTitle=null, highlight=null, articleAbstract=

不适气温与空气污染都会增加慢性阻塞性肺疾病（简称慢阻肺）的健康风险，为评价气温、PM_2.5和O₃的单效应影响，以及气温与PM_2.5（或O₃）交互作用、PM_2.5与O₃交互作用的影响，采用广义相加模型，收集2014~2019年天津市居民慢阻肺住院数据，进行定量分析．结果表明，气温对天津市慢阻肺住院人数有着显著影响，低温效应明显强于高温效应，且低温对女性及老年人群影响更大．在最大滞后效应下，PM_2.5和O₃每增加10μg/m³，慢阻肺住院风险增加1.23%（95%CI：0.79%，1.67%）和0.90%（95%CI：0.58%，1.23%）．交互作用结果分析显示，低温与高浓度PM_2.5存在协同加强效应，高温与高浓度O₃存在协同加强效应，且高温时，随着PM_2.5浓度的升高，O₃暴露带来的慢阻肺住院风险会增强．极端天气频发，应加强关注不适气温与空气污染对慢阻肺健康风险的影响，采取措施做好早期预警和提前干预．

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王晓佳（1990-），女，内蒙古，工程师，博士，主要从事环境与健康气象研究．发表论文10余篇．wangxj90@qq.com.

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王晓佳（1990-），女，内蒙古，工程师，博士，主要从事环境与健康气象研究．发表论文10余篇．wangxj90@qq.com.

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