Article(id=1314918410392269470, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918356222829028, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1742313600000, receivedDateStr=2025-03-19, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791430579040, onlineDateStr=2026-10-08, pubDate=1763568000000, pubDateStr=2025-11-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791430579040, onlineIssueDateStr=2026-10-08, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791430579040, creator=13701087609, updateTime=1791430579040, updator=13701087609, issue=Issue{id=1314918356222829028, tenantId=1146029695717560320, journalId=1234093305789726721, year='2025', volume='45', issue='11', pageStart='5921', pageEnd='6512', issueExtLink='null', onlineDate='null', pubDate='1763568000000', pubDateStr='2025-11-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791430566125, creator='13701087609', updateTime=1791431596967, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1314922679942078535, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918356222829028, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1314922679942078536, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314918356222829028, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=6411, endPage=6422, ext={EN=ArticleExt(id=1314918410610373279, articleId=1314918410392269470, tenantId=1146029695717560320, journalId=1234093305789726721, language=EN, title=Accurate exposure modeling and health risks of heavy metals in mainstream smoke of best-selling cigarettes: A case study in Hubei Province, columnId=1234106388687934088, journalTitle=China Environmental Science, columnName=Environmental Toxicology and Environmental Health, runingTitle=null, highlight=null, articleAbstract=

Heavy metals in mainstream cigarette smoke can pose risks to smokers and other exposed populations. Although international standards have released to control of hazardous substances in tobacco products, no recognized standard currently exists for quantitative management of heavy metals in cigarettes. The scientific and precise exposure modeling and health risk assessment of heavy metals in mainstream smoke from best-selling cigarettes could provide theoretical support for developing targeted quantitative control strategies on both government and smoker scales. The basic levels of arsenic (As), cadmium (Cd), and lead (Pb) in the 15best-selling brands of cigarettes in Hubei Province were investigated, and a comparative analysis of the content in different cigarette types was conducted. Further, the human respiratory tract model was introduced to calculate the deposition rates of particulate matter of different sizes in mainstream smoke, and then the deposition doses in each part of the human respiratory tract were estimated. Finally, integratedly using inhalation exposure feature of mainstream smoke, the regional exposure parameters and triangular fuzzy numbers, an optimized health risk assessment model was established and carried out. The results showed that the mean values and ranges of As, Cd, and Pb in mainstream smoke were as follows: Cd (1.95mg/kg, 0.623~2.81mg/kg), As (1.33mg/kg, 0.172~2.88mg/kg) and Pb (1.13mg/kg, 0.413~1.65mg/kg). PM_2.5 accounted for 75%~85% of the particulate matter released from mainstream smoke, and the deposition rates in respiratory tract after fuzzy number operation were [27.48%, 29.19%] for PM_2.5and [28.50%, 30.46%] for PM₅. The carcinogenic risk of As, Cd, and Pb in mainstream smoke was ranked as follows: Cd (Ⅱ-Ⅴ) > As (Ⅱ-Ⅳ) > Pb (Ⅰ), hence As and Cd were identified as the priority heavy metals for control. Based on the annual mortality rates attributed to tobacco consumption, the standard value of Class Ⅱ risk (1×10^-5) was chosen as the risk control value for daily smokers. And according to the inverse calculation of the total exposure of mainstream smoke, the daily smoking amount based on this survey should be controlled at 3~4 cigarettes for thick cigarettes and menthol cigarettes, and 1~2 cigarettes for thin cigarettes. Advise all types of smokers to quit smoking as soon as possible.

, authors=Fei LI¹, Jin-yuan GUO¹, Wen-zhuo DENG¹, Mian WU¹, Rui-zhi ZHANG², Chao-yang LIU¹, Jing-dong ZHANG^{1, *}, authorsList=Fei LI, Jin-yuan GUO, Wen-zhuo DENG, Mian WU, Rui-zhi ZHANG, Chao-yang LIU, Jing-dong ZHANG, authorCompany=null, correspAuthors=Jing-dong ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1314918411981910688, articleId=1314918410392269470, tenantId=1146029695717560320, journalId=1234093305789726721, language=CN, title=畅销香烟主烟气流中重金属的精准暴露模拟与健康风险研究——以湖北省烟民为例, columnId=1234106394006311784, journalTitle=中国环境科学, columnName=环境毒理与健康, runingTitle=null, highlight=null, articleAbstract=

调查了湖北省15种畅销品牌烟草中砷（As）、镉（Cd）、铅（Pb）的基本含量,探究重金属的分布特征.而后利用人体呼吸道模型计算主烟气流中不同粒径颗粒物进入人体呼吸道中的沉积率,测度人体呼吸道各部分中的沉积剂量.最后基于主烟气流的吸入暴露途径,优选区域暴露参数和三角模糊数构建精准健康风险评估模型.研究结果表明,香烟烟丝中As、Cd、Pb的测定结果均值及范围为:Cd（1.95mg/kg, 0.623~2.81mg/kg）、As（1.33mg/kg, 0.172~2.88mg/kg）、Pb（1.13mg/kg, 0.413~1.65mg/kg）.PM_2.5占主烟气流释放颗粒物的75~85%,经过三角模糊化后PM_2.5在呼吸道内沉积率为[27.48%, 29.19%],PM₅为[28.50%, 30.46%].香烟主烟气流中As、Cd、Pb的致癌风险排序为:Cd（Ⅱ级风险~Ⅴ级风险）>As（Ⅱ级风险~Ⅳ级风险）>Pb（极低风险）,As和Cd被识别为优先控制重金属.综合选用Ⅱ级风险标准值（1×10^-5）作为每日吸烟者风险管控值,根据主烟气流暴露限值反算,对于粗支烟和薄荷烟,每日吸烟量应控制在3~4支;对于细支烟,每日吸烟量应控制在1~2支,劝解各类烟民尽快戒烟.

, authors=李飞¹, 郭锦媛¹, 邓文倬¹, 吴冕¹, 张睿智², 刘朝阳¹, 张敬东^{1, *}, authorsList=李飞, 郭锦媛, 邓文倬, 吴冕, 张睿智, 刘朝阳, 张敬东, authorCompany=null, correspAuthors=张敬东, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=RYE/oA3qTUkNJNzsQ/Sjkw==, magXml=mC6jvXF6eDGZyhZER6YaDQ==, pdfUrl=null, pdf=7n+/Q+QKCmV+UeRqbFj3fg==, pdfFileSize=962029, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=jy4v82e0px/d/zq2asvADQ==, mapNumber=null, fund=null)}, authors=[Author(id=1314918412392952488, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918410392269470, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=lifei@zuel.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1314918412472644266, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918410392269470, authorId=1314918412392952488, language=EN, stringName=Fei LI, firstName=Fei, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Research Center for Environment and Health, School of Information Engineering, Zhongnan University of Economics and Law, Wuhan 430073, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1314918412556530347, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314918410392269470, authorId=1314918412392952488, language=CN, stringName=李飞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.中南财经政法大学信息工程学院，环境与健康研究中心，湖北 武汉 430073, bio={"content":"

李飞（1986-），男，河南新乡人，教授，博士，主要研究方向为环境监测、环境健康风险管理、环境与健康大数据、环境修复技术.发表论文100余篇．lifei@zuel.edu.cn.

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李飞（1986-），男，河南新乡人，教授，博士，主要研究方向为环境监测、环境健康风险管理、环境与健康大数据、环境修复技术.发表论文100余篇．lifei@zuel.edu.cn.

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