Article(id=1314917533447192708, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314917454552327005, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1733068800000, receivedDateStr=2024-12-02, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791430369960, onlineDateStr=2026-10-08, pubDate=1752940800000, pubDateStr=2025-07-20, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791430369960, onlineIssueDateStr=2026-10-08, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791430369960, creator=13701087609, updateTime=1791430369960, updator=13701087609, issue=Issue{id=1314917454552327005, tenantId=1146029695717560320, journalId=1234093305789726721, year='2025', volume='45', issue='7', pageStart='3553', pageEnd='4144', issueExtLink='null', onlineDate='null', pubDate='1752940800000', pubDateStr='2025-07-20', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791430351150, creator='13701087609', updateTime=1791431931754, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1314924084186669335, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314917454552327005, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1314924084186669336, tenantId=1146029695717560320, journalId=1234093305789726721, issueId=1314917454552327005, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3994, endPage=4002, ext={EN=ArticleExt(id=1314917535267520645, articleId=1314917533447192708, tenantId=1146029695717560320, journalId=1234093305789726721, language=EN, title=Toxic effects and mechanisms of thin-bedded molybdenum disulphide on Microcystis aeruginosa, columnId=1234106388687934088, journalTitle=China Environmental Science, columnName=Environmental Toxicology and Environmental Health, runingTitle=null, highlight=null, articleAbstract=

This study investigated the aquatic toxicity effects and underlying mechanisms of thin-layer molybdenum disulfide (MoS₂) using the Microcystis aeruginosa as a model organism. The results demonstrated that various concentration of MoS₂ (0.01~50mg/L) significantly inhibited algal growth during short-term exposure (0~7 days), with the highest inhibition rate of 75% observed in the 50mg/L group after 6days of cultivation. Throughout the 7-day exposure phase, MoS₂ exhibited strong dose-dependent inhibitory effects on pigment biosynthesis and biomass accumulation, as evidenced by concentration-responsive reduction in pigment content (<0.5mg/L), polysaccharides and proteins (<0.05mg/mL), and lipids synthesis (<2×10⁵ fluorescence units). When exposure duration extended to 14~21 days, the observed inhibitory effects gradually alleviated, though high-concentration treatments (50 and 10mg/L) still maintained substantial growth inhibition. Mechanistic analysis revealed that photoactivated MoS₂ nanoparticles generated reactive oxygen species (ROS), triggering acute/chronic oxidative stress in algal cells. During the initial 0~7 day exposure, intracellular ROS levels, superoxide dismutase (SOD) activity, and extracellular polymeric substances (EPS) secretion all significantly increased. These oxidative stress indicators progressively normalized during prolonged exposure (14~21 days). However, under high-concentration exposure conditions (50 and 10mg/L), the oxidative stress response exceeded cellular defense capacity, ultimately causing irreversible membrane damage. These findings provide fundamental data and theoretical support for ecological risk assessment of MoS₂ nanomaterials in aquatic environments.

, authors=Yi-tao MA^{1, 2}, Ke-meng SHENG¹, Zhi-xiang XU^{1, 2, *}, Si-yuan LI¹, Hao LU¹, Cai-qing LI¹, Jin-rui XIONG¹, Xue-jun PAN^{1, 2}, authorsList=Yi-tao MA, Ke-meng SHENG, Zhi-xiang XU, Si-yuan LI, Hao LU, Cai-qing LI, Jin-rui XIONG, Xue-jun PAN, authorCompany=null, correspAuthors=Zhi-xiang XU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1314917535787614342, articleId=1314917533447192708, tenantId=1146029695717560320, journalId=1234093305789726721, language=CN, title=薄层二硫化钼对铜绿微囊藻的毒性效应及机制, columnId=1234106394006311784, journalTitle=中国环境科学, columnName=环境毒理与健康, runingTitle=null, highlight=null, articleAbstract=

本研究以铜绿微囊藻（Microcystis aeruginosa）为受试生物，探究薄层二硫化钼（MoS₂）的水生毒性效应及相关作用机制．结果表明，不同浓度MoS₂处理组（0.01~50mg/L）在短期内（0~7d）抑制藻胞生长，其中在培养6d后50mg/L MoS₂对藻胞生长达到最高抑制作用（75%）．在7d内MoS₂对藻胞色素、有机物合成表现出较强抑制作用（色素低于0.5mg/L，多糖和蛋白质低于0.05mg/mL，脂质低于2×10⁵FU），且浓度越高抑制作用越强．随暴露时间延长至14~21d，抑制作用相对减轻，但高浓度处理组（50，10mg/L）仍对藻胞生长存在较强毒害作用．MoS₂光照产生ROS攻击藻胞使其发生急性/慢性氧化应激，0~7d内藻胞活性氧（ROS）、超氧化物歧化酶活性（SOD）以及胞外分泌物（EPS）升高，暴露14~21d后氧化应激水平逐渐恢复．然而，高浓度（50，10mg/L）暴露下，氧化应激反应超过藻胞的承载能力使其发生膜损伤．研究结果为MoS₂纳米材料的水生生态毒性和评估提供基础数据和理论支撑．

, authors=马乙洮^{1, 2}, 盛科梦¹, 胥志祥^{1, 2, *}, 李思沅¹, 卢浩¹, 李彩情¹, 熊金瑞¹, 潘学军^{1, 2}, authorsList=马乙洮, 盛科梦, 胥志祥, 李思沅, 卢浩, 李彩情, 熊金瑞, 潘学军, authorCompany=null, correspAuthors=胥志祥, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=e/9rL8Btb9MGJbwi9rBtBQ==, magXml=cm3Kh04TgSDWaGl9W8TUkw==, pdfUrl=null, pdf=ZalVMV0V3f+LK7RsYP4pkQ==, pdfFileSize=2369415, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=/S4f9Z2m1XGWZdacrZODVA==, mapNumber=null, fund=null)}, authors=[Author(id=1314917536274153614, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314917533447192708, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=2942169341@qq.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1314917536358039697, tenantId=1146029695717560320, journalId=1234093305789726721, articleId=1314917533447192708, authorId=1314917536274153614, language=EN, stringName=Yi-tao MA, firstName=Yi-tao, middleName=null, lastName=MA, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=^1.Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China
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^2.西南联合研究生院，云南 昆明 650092, bio={"content":"

马乙洮（2001-），女，云南大理人，昆明理工大学硕士研究生，主要从事纳米材料生态安全与健康风险研究．发表论文2篇．2942169341@qq.com.

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马乙洮（2001-），女，云南大理人，昆明理工大学硕士研究生，主要从事纳米材料生态安全与健康风险研究．发表论文2篇．2942169341@qq.com.

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