Article(id=1192149545795600460, tenantId=1146029695717560320, journalId=1192105938417971205, issueId=1192149543010582589, articleNumber=null, orderNo=null, doi=10.13343/j.cnki.wsxb.20250214, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1742227200000, receivedDateStr=2025-03-18, revisedDate=null, revisedDateStr=null, acceptedDate=1744214400000, acceptedDateStr=2025-04-10, onlineDate=1762160200785, onlineDateStr=2025-11-03, pubDate=1756915200000, pubDateStr=2025-09-04, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1762160200785, onlineIssueDateStr=2025-11-03, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1762160200785, creator=13701087609, updateTime=1762160200785, updator=13701087609, issue=Issue{id=1192149543010582589, tenantId=1146029695717560320, journalId=1192105938417971205, year='2025', volume='65', issue='10', pageStart='4241', pageEnd='4713', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1762160200113, creator=13701087609, updateTime=1762160638682, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1192151382586175735, tenantId=1146029695717560320, journalId=1192105938417971205, issueId=1192149543010582589, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1192151382586175736, tenantId=1146029695717560320, journalId=1192105938417971205, issueId=1192149543010582589, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=4528, endPage=4536, ext={EN=ArticleExt(id=1192149546005315662, articleId=1192149545795600460, tenantId=1146029695717560320, journalId=1192105938417971205, language=EN, title=Biological characteristics of the transposon insertion mutant of TonB in Avibacterium paragallinarum, columnId=1192149543992045670, journalTitle=Acta Microbiologica Sinica, columnName=Research Article, runingTitle=null, highlight=null, articleAbstract=

[Objective] To elucidate the virulence-associated biological characteristics of a transposon insertion mutant with impaired biofilm formation of Avibacterium paragallinarum. [Methods] The wild-type strain JZIC-005 and a biofilm-deficient mutant Tn-1504 (from a pre-established transposon mutant library) were selected for determination of insertion sites biological characterization. [Results] PCR results demonstrated site-specific transposon integration into TonB of A. paragallinarum. While mutant Tn-1504 exhibited no growth defects compared with the wild-type strain (P>0.05), it demonstrated reductions of 46.57% in adhesion to DF-1 cells and 77.61% in cellular invasion. Cytotoxicity assays revealed a 34.97% reduction of Tn-1504 in inducing host cell damage. All of the above phenotypic differences were statistically significant (P<0.01). [Conclusion] We demonstrate that inactivation of TonB specifically impairs the adhesion, invasion, and virulence characteristics of A. paragallinarum, providing a key target for analyzing the pathogenic mechanism and developing anti-virulence strategies for this pathogen.

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【目的】 探究生物被膜形成能力减弱的转座子插入突变株对副鸡禽杆菌生物学特性的调控作用。 【方法】 以野生株JZIC-005和转座子突变株Tn-1504 (从突变库中筛选获得，生物被膜形成能力减弱)为研究对象，进行插入位点鉴定及生物学特性分析。 【结果】 PCR验证显示转座子特异性插入副鸡禽杆菌TonB基因中。与野生株相比，突变株Tn-1504的增殖能力未发生显著改变(P>0.05)，但对DF-1细胞的黏附率降低46.57%，侵袭率下降77.61%，细胞毒性减弱34.97%。上述表型差异均具有统计学意义(P<0.01)。 【结论】 本研究证实TonB基因失活可特异性削弱副鸡禽杆菌的宿主黏附、侵袭及毒性特征，为解析该病原致病机制及抗毒力策略开发提供了关键靶点。

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issue=10, pageStart=115, pageEnd=116, url=null, language=null, rfNumber=[1], rfOrder=1, authorNames=WU LL, journalName=China Animal Husbandry, refType=null, unstructuredReference=WU LL. Clinical symptoms and recent advances in diagnosis and treatment of infectious coryza in chickens[J]. China Animal Husbandry, 2023, (10): 115-116 (in Chinese)., articleTitle=null, refAbstract=null), Reference(id=1192161078768447980, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=1962, volume=23, issue=null, pageStart=85, pageEnd=95, url=null, language=null, rfNumber=[2], rfOrder=2, authorNames=PAGE LA, journalName=American Journal of Veterinary Research, refType=null, unstructuredReference=PAGE LA. Haemophilus infections in chickens. I. characteristics of 12 Haemophilus isolates recovered from diseased chickens[J]. American Journal of Veterinary Research, 1962, 23: 85-95., articleTitle=Haemophilus infections in chickens. I. characteristics of 12 Haemophilus isolates recovered from diseased chickens, refAbstract=null), Reference(id=1192161078814585325, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=39, issue=5, pageStart=131, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=3, authorNames=KILIC T, BALI EB, journalName=World Journal of Microbiology & Biotechnology, refType=null, unstructuredReference=KILIC T, BALI EB. Biofilm control strategies in the light of biofilm-forming microorganisms[J]. World Journal of Microbiology & Biotechnology, 2023, 39(5): 131., articleTitle=Biofilm control strategies in the light of biofilm-forming microorganisms, refAbstract=null), Reference(id=1192161078869111278, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2024, volume=175, issue=3, pageStart=104172, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=4, authorNames=ARANSIOLA SA, SELVARAJ B, MADDELA NR, journalName=Research in Microbiology, refType=null, unstructuredReference=ARANSIOLA SA, SELVARAJ B, MADDELA NR. Bacterial biofilm formation and anti-biofilm strategies[J]. Research in Microbiology, 2024, 175(3): 104172., articleTitle=Bacterial biofilm formation and anti-biofilm strategies, refAbstract=null), Reference(id=1192161078932025839, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=1994, volume=176, issue=8, pageStart=2326, pageEnd=2338, url=null, language=null, rfNumber=[5], rfOrder=5, authorNames=JASKULA JC, LETAIN TE, ROOF SK, SKARE JT, POSTLE K, journalName=Journal of Bacteriology, refType=null, unstructuredReference=JASKULA JC, LETAIN TE, ROOF SK, SKARE JT, POSTLE K. Role of the TonB amino terminus in energy transduction between membranes[J]. Journal of Bacteriology, 1994, 176(8): 2326-2338., articleTitle=Role of the TonB amino terminus in energy transduction between membranes, refAbstract=null), Reference(id=1192161078982357488, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2007, volume=20, issue=3, pageStart=467, pageEnd=483, url=null, language=null, rfNumber=[6], rfOrder=6, authorNames=CHU BCH, PEACOCK RS, VOGEL HJ, journalName=Biometals, refType=null, unstructuredReference=CHU BCH, PEACOCK RS, VOGEL HJ. Bioinformatic analysis of the TonB protein family[J]. Biometals, 2007, 20(3): 467-483., articleTitle=Bioinformatic analysis of the TonB protein family, refAbstract=null), Reference(id=1192161079028494833, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=7, authorNames=宫金烁, journalName=null, refType=null, unstructuredReference=宫金烁. 维氏气单胞菌TH0426株Fur基因的缺失及其功能的初探[D]. 长春: 吉林农业大学, 2023., articleTitle=维氏气单胞菌TH0426株Fur基因的缺失及其功能的初探, refAbstract=null), Reference(id=1192161079083020786, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=8, authorNames=GONG JS, journalName=null, refType=null, unstructuredReference=GONG JS. Construction and characterization of Fur deleted mutant in Aeromonas veronii TH0426[D]. Changchun: Jilin Agricultural University, 2023 (in Chinese)., articleTitle=null, refAbstract=null), Reference(id=1192161079129158131, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2024, volume=580, issue=null, pageStart=740361, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=9, authorNames=GONG JS, WANG YD, JIANG YL, ZHANG D, CAI YN, SHAN XF, GONG H, DONG H, journalName=Aquaculture, refType=null, unstructuredReference=GONG JS, WANG YD, JIANG YL, ZHANG D, CAI YN, SHAN XF, GONG H, DONG H. Ferric uptake regulator (fur) affects the pathogenicity of Aeromonas veronii TH0426 by regulating flagellar assembly and biofilm formation[J]. Aquaculture, 2024, 580: 740361., articleTitle=Ferric uptake regulator (fur) affects the pathogenicity of Aeromonas veronii TH0426 by regulating flagellar assembly and biofilm formation, refAbstract=null), Reference(id=1192161079196266996, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2024, volume=14, issue=1, pageStart=13, pageEnd=22, url=null, language=null, rfNumber=[9], rfOrder=10, authorNames=SCHMITZ M, QUERQUES I, journalName=FEBS Open Bio, refType=null, unstructuredReference=SCHMITZ M, QUERQUES I. DNA on the move: mechanisms, functions and applications of transposable elements[J]. FEBS Open Bio, 2024, 14(1): 13-22., articleTitle=DNA on the move: mechanisms, functions and applications of transposable elements, refAbstract=null), Reference(id=1192161079284347381, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2011, volume=39, issue=13, pageStart=7820, pageEnd=7823, url=null, language=null, rfNumber=[10], rfOrder=11, authorNames=贺云霞, 徐慧, 叶飞, 孙慧玲, 王宏俊, 龚玉梅, 张莉, 黄秀芬, 张培君, journalName=安徽农业科学, refType=null, unstructuredReference=贺云霞, 徐慧, 叶飞, 孙慧玲, 王宏俊, 龚玉梅, 张莉, 黄秀芬, 张培君. 副猪嗜血杆菌EZ-Tn5转座子插入突变体库的构建及减毒株的筛选[J]. 安徽农业科学, 2011, 39(13): 7820-7823, 7831., articleTitle=副猪嗜血杆菌EZ-Tn5转座子插入突变体库的构建及减毒株的筛选, refAbstract=null), Reference(id=1192161079347261942, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2011, volume=39, issue=13, pageStart=7820, pageEnd=7823, url=null, language=null, rfNumber=[10], rfOrder=12, authorNames=HE YX, XU H, YE F, SUN HL, WANG HJ, GONG YM, ZHANG L, HUANG XF, ZHANG PJ, journalName=Journal of Anhui Agricultural Sciences, refType=null, unstructuredReference=HE YX, XU H, YE F, SUN HL, WANG HJ, GONG YM, ZHANG L, HUANG XF, ZHANG PJ. Construction of mutation library in Haemophilus parasuis by inserting Tn5 transposon and the screening of attenuated strain[J]. Journal of Anhui Agricultural Sciences, 2011, 39(13): 7820-7823, 7831 (in Chinese)., articleTitle=null, refAbstract=null), Reference(id=1192161079426953719, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2025, volume=302, issue=null, pageStart=110410, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=13, authorNames=GUO MJ, WANG HN, ZHANG H, BO ZY, ZHANG CC, ZHANG XR, WU YT, journalName=Veterinary Microbiology, refType=null, unstructuredReference=GUO MJ, WANG HN, ZHANG H, BO ZY, ZHANG CC, ZHANG XR, WU YT. Identifcation of the genes involved in biofilm formation of Avibacterium paragallinarum using random transposon mutagenesis[J]. Veterinary Microbiology, 2025, 302: 110410., articleTitle=Identifcation of the genes involved in biofilm formation of Avibacterium paragallinarum using random transposon mutagenesis, refAbstract=null), Reference(id=1192161079494062584, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2020, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=14, authorNames=陶虹, 孙洁, 张彩虹, journalName=null, refType=null, unstructuredReference=陶虹, 孙洁, 张彩虹. 鸡传染性鼻炎检疫技术规范: SN/T 1556—2020 [S]. 北京: 中国标准出版社, 2020., articleTitle=null, refAbstract=null), Reference(id=1192161079561171449, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2020, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=15, authorNames=TAO H, SUN J, ZHANG CH, journalName=null, refType=null, unstructuredReference=TAO H, SUN J, ZHANG CH. Technical specification for quarantine of avian infectious coryza: SN/T 1556—2020 [S]. Beijing: Standards Press of China, 2020 (in Chinese)., articleTitle=null, refAbstract=null), Reference(id=1192161079632474618, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=16, authorNames=张小芸, journalName=null, refType=null, unstructuredReference=张小芸. 副溶血弧菌运动性相关基因筛选及对其毒力影响的研究[D]. 上海: 中国农业科学院, 2023., articleTitle=副溶血弧菌运动性相关基因筛选及对其毒力影响的研究, refAbstract=null), Reference(id=1192161079787663867, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=17, authorNames=ZHANG XY, journalName=null, refType=null, unstructuredReference=ZHANG XY. Screening and identification of motility-associated genes and analysis of their effects on its virulence of Vibrio parahaemolyticus [D]. Shanghai: Chinese Academy of Agricultural Sciences, 2023 (in Chinese)., articleTitle=null, refAbstract=null), Reference(id=1192161079867355644, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2013, volume=55, issue=null, pageStart=21, pageEnd=27, url=null, language=null, rfNumber=[14], rfOrder=18, authorNames=HAN XG, BAI H, LIU L, DONG HL, LIU R, SONG J, DING C, QI KZ, LIU HW, YU SQ, journalName=Microbial Pathogenesis, refType=null, unstructuredReference=HAN XG, BAI H, LIU L, DONG HL, LIU R, SONG J, DING C, QI KZ, LIU HW, YU SQ. The luxS gene functions in the pathogenesis of avian pathogenic Escherichia coli [J]. Microbial Pathogenesis, 2013, 55: 21-27., articleTitle=The luxS gene functions in the pathogenesis of avian pathogenic Escherichia coli, refAbstract=null), Reference(id=1192161079984796157, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2018, volume=8, issue=null, pageStart=242, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=19, authorNames=YU HT, DING XL, SHANG LJ, ZENG XF, LIU HB, LI N, HUANG S, WANG YM, WANG G, CAI S, CHEN MX, LEVESQUE CL, JOHNSTON LJ, QIAO SY, journalName=Frontiers in Cellular and Infection Microbiology, refType=null, unstructuredReference=YU HT, DING XL, SHANG LJ, ZENG XF, LIU HB, LI N, HUANG S, WANG YM, WANG G, CAI S, CHEN MX, LEVESQUE CL, JOHNSTON LJ, QIAO SY. Protective ability of biogenic antimicrobial peptide microcin J25 against enterotoxigenic Escherichia coli-induced intestinal epithelial dysfunction and inflammatory responses IPEC-J2 cells[J]. Frontiers in Cellular and Infection Microbiology, 2018, 8: 242., articleTitle=Protective ability of biogenic antimicrobial peptide microcin J25 against enterotoxigenic Escherichia coli-induced intestinal epithelial dysfunction and inflammatory responses IPEC-J2 cells, refAbstract=null), Reference(id=1192161080488112638, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2010, volume=14, issue=2, pageStart=218, pageEnd=224, url=null, language=null, rfNumber=[16], rfOrder=20, authorNames=KEHL-FIE TE, SKAAR EP, journalName=Current Opinion in Chemical Biology, refType=null, unstructuredReference=KEHL-FIE TE, SKAAR EP. Nutritional immunity beyond iron: a role for manganese and zinc[J]. Current Opinion in Chemical Biology, 2010, 14(2): 218-224., articleTitle=Nutritional immunity beyond iron: a role for manganese and zinc, refAbstract=null), Reference(id=1192161080546832895, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2018, volume=7, issue=null, pageStart=535, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=21, authorNames=MOUMÈNE A, GONZALEZ-RIZZO S, LEFRANÇOIS T, VACHIÉRY N, MEYER DF, journalName=Frontiers in Cellular and Infection Microbiology, refType=null, unstructuredReference=MOUMÈNE A, GONZALEZ-RIZZO S, LEFRANÇOIS T, VACHIÉRY N, MEYER DF. Iron starvation conditions upregulate Ehrlichia ruminantium type IV secretion system, tr1 transcription factor and map1 genes family through the master regulatory protein ErxR[J]. Frontiers in Cellular and Infection Microbiology, 2018, 7: 535., articleTitle=Iron starvation conditions upregulate Ehrlichia ruminantium type IV secretion system, tr1 transcription factor and map1 genes family through the master regulatory protein ErxR, refAbstract=null), Reference(id=1192161080605553152, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2002, volume=184, issue=6, pageStart=1640, pageEnd=1648, url=null, language=null, rfNumber=[18], rfOrder=22, authorNames=HIGGS PI, LETAIN TE, MERRIAM KK, BURKE NS, PARK H, KANG C, POSTLE K, journalName=Journal of Bacteriology, refType=null, unstructuredReference=HIGGS PI, LETAIN TE, MERRIAM KK, BURKE NS, PARK H, KANG C, POSTLE K. TonB interacts with nonreceptor proteins in the outer membrane of Escherichia coli [J]. Journal of Bacteriology, 2002, 184(6): 1640-1648., articleTitle=TonB interacts with nonreceptor proteins in the outer membrane of Escherichia coli, refAbstract=null), Reference(id=1192161080660079105, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2022, volume=90, issue=1, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=23, authorNames=PARKER AC, SEALS NL, BACCANALE CL, ROCHA ER, journalName=Infection and Immunity, refType=null, unstructuredReference=PARKER AC, SEALS NL, BACCANALE CL, ROCHA ER. Analysis of six tonB gene homologs in Bacteroides fragilis revealed that tonB3 is essential for survival in experimental intestinal colonization and intra-abdominal infection[J]. Infection and Immunity, 2022, 90(1): e0046921., articleTitle=Analysis of six tonB gene homologs in Bacteroides fragilis revealed that tonB3 is essential for survival in experimental intestinal colonization and intra-abdominal infection, refAbstract=null), Reference(id=1192161080718799362, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=45, issue=3, pageStart=120, pageEnd=124, url=null, language=null, rfNumber=[20], rfOrder=24, authorNames=孙晨明, 徐亚亚, 朱庭芳, 王梓霏, 袁华根, journalName=中国家禽, refType=null, unstructuredReference=孙晨明, 徐亚亚, 朱庭芳, 王梓霏, 袁华根. 禽致病性大肠杆菌tonB基因缺失株的构建及其生物学特性研究[J]. 中国家禽, 2023, 45(3): 120-124., articleTitle=禽致病性大肠杆菌tonB基因缺失株的构建及其生物学特性研究, refAbstract=null), Reference(id=1192161080773325315, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, doi=null, pmid=null, pmcid=null, year=2023, volume=45, issue=3, pageStart=120, pageEnd=124, url=null, language=null, rfNumber=[20], rfOrder=25, authorNames=SUN CM, XU YY, ZHU TF, WANG ZF, YUAN HG, journalName=China Poultry, refType=null, unstructuredReference=SUN CM, XU YY, ZHU TF, WANG ZF, YUAN HG. 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Primers related to transposon insertion identification

, figureFileSmall=null, figureFileBig=null, tableContent=

引物 Primers name	引物序列 Primer sequences (5′→3′)	PCR产物长度 Lenth of PCR products (bp)
Erm-F	GACGATATTCTCGATTGACC	484
Erm-R	TTAACGACGAAACTGGCTAA
Apg-F	TGAGGGTAGTCTTGCACGCGAAT	510
Apg-R	CAAGGTATCGATCGTCTCTCTACT

), ArticleFig(id=1192161078231577061, tenantId=1146029695717560320, journalId=1192105938417971205, articleId=1192149545795600460, language=CN, label=表1, caption=

转座子插入鉴定的相关引物

, figureFileSmall=null, figureFileBig=null, tableContent=

引物 Primers name	引物序列 Primer sequences (5′→3′)	PCR产物长度 Lenth of PCR products (bp)
Erm-F	GACGATATTCTCGATTGACC	484
Erm-R	TTAACGACGAAACTGGCTAA
Apg-F	TGAGGGTAGTCTTGCACGCGAAT	510
Apg-R	CAAGGTATCGATCGTCTCTCTACT

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