Article(id=1317885750264320332, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, articleNumber=null, orderNo=null, doi=10.12449/JCH260823, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1771948800000, receivedDateStr=2026-02-25, revisedDate=null, revisedDateStr=null, acceptedDate=1774540800000, acceptedDateStr=2026-03-27, onlineDate=1792138047995, onlineDateStr=2026-10-16, pubDate=1787587200000, pubDateStr=2026-08-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792138047995, onlineIssueDateStr=2026-10-16, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792138047995, creator=13701087609, updateTime=1792138047995, updator=13701087609, issue=Issue{id=1317885672153797495, tenantId=1146029695717560320, journalId=1316781422847033486, year='2026', volume='42', issue='8', pageStart='1745', pageEnd='2000', issueExtLink='null', onlineDate='null', pubDate='1787587200000', pubDateStr='2026-08-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792138029373, creator='13701087609', updateTime=1792138608261, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317888100290900262, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317888100290900263, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1902, endPage=1907, ext={EN=ArticleExt(id=1317885750604058958, articleId=1317885750264320332, tenantId=1146029695717560320, journalId=1316781422847033486, language=EN, title=Clinical application of transparent cap-assisted peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy for large common bile duct stones, columnId=1317885750486618445, journalTitle=Journal of Clinical Hepatology, columnName=Biliary Disease, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the safety and efficacy of transparent cap-assisted peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy （EHL）.
Methods A retrospective analysis was performed for the clinical data of 60 patients with large common bile duct stones who were admitted to Department of Gastroenterology，Jilin People’s Hospital，from May 1，2023 to January 31，2026，and according to the treatment method，the patients were divided into transparent cap-assisted peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy group and peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy group，with 30 patients in each group. The two groups were compared in terms of the rate of successful single-session stone fragmentation and removal，procedural time，duration of electrohydraulic lithotripsy，clinical success rate，and complications. The independent-samples t test or the Mann-Whitney U test was used for comparison of continuous data between two groups，and the chi-square test or the Fisher’s exact test was used for comparison of categorical data between two groups.
Results Compared with the peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy group，the transparent cap-assisted peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy group had a significantly higher technical success rate （83.33% vs 60.00%，χ2=4.022，P=0.045） and significantly shorter procedural time ［46.00 （42.25 — 49.00） min vs 54.50 （42.00 — 65.00） min，Z=2.012，P=0.044］ and duration of electrohydraulic lithotripsy ［8.00 （6.25 — 11.75） min vs 13.50 （9.25 — 17.75） min，Z=2.749，P=0.006］. Both groups achieved a clinical success rate of 100%，with no significant difference in the incidence rate of complications （P>0.05）.
Conclusion Transparent cap-assisted peroral cholangiopancreatoscopy-guided electrohydraulic lithotripsy has a high rate of successful single-session stone fragmentation and removal and a short procedural time，with good safety and efficacy，and therefore，it holds promise for clinical application.
, authors=Liying Tao, Hongguang Wang, Qingmei Guo, Chong Pang, Yundong Shi, Sijie Guo, Tianjiao Jia, Yan Chen, Jiani Zhou, Shu Che, authorsList=Liying Tao, Hongguang Wang, Qingmei Guo, Chong Pang, Yundong Shi, Sijie Guo, Tianjiao Jia, Yan Chen, Jiani Zhou, Shu Che, authorCompany=null, correspAuthors=Hongguang Wang, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317885753733009746, articleId=1317885750264320332, tenantId=1146029695717560320, journalId=1316781422847033486, language=CN, title=透明帽辅助经口胆胰管镜直视液电碎石在胆总管巨大结石治疗中的作用, columnId=1317885750675362127, journalTitle=临床肝胆病杂志, columnName=胆道疾病, runingTitle=null, highlight=null, articleAbstract=
目的 探讨透明帽辅助经口胆胰管镜直视液电碎石的安全性和有效性。
方法 回顾性分析2023年5月1日—2026年1月31日吉林市人民医院消化内科收治的60例胆总管巨大结石患者的临床资料，根据治疗方式分为透明帽辅助经口胆胰管镜直视液电碎石组和经口胆胰管镜直视液电碎石组，每组各30例。比较两组患者的手术一次性完整碎石取石技术成功率、手术操作时间、液电碎石时间、手术临床成功率、并发症等指标。计量资料两组间比较采用成组t检验或Mann-Whitney U检验。计数资料两组间比较采用χ2检验或Fisher精确概率法。
结果 与经口胆胰管镜直视液电碎石组相比，透明帽辅助经口胆胰管镜直视液电碎石组的技术成功率（83.33% vs 60.00%，χ2=4.022，P=0.045）显著升高，手术操作时间［46.00（42.25～49.00）min vs 54.50（42.00～65.00）min，Z=2.012，P=0.044］、液电碎石时间［8.00（6.25～11.75）min vs 13.50（9.25～17.75）min，Z=2.749，P=0.006］显著缩短；两组的手术临床成功率均为100%，并发症的发生率差异均无统计学意义（P值均>0.05）。
结论 透明帽辅助经口胆胰管镜直视液电碎石的一次性完整碎石取石技术成功率高，操作时间缩短，且安全有效，值得临床进一步推广。
, authors=陶丽莹, 王宏光, 郭庆梅, 庞崇, 施云东, 郭思捷, 贾天娇, 陈岩, 周佳妮, 车舒, authorsList=陶丽莹, 王宏光, 郭庆梅, 庞崇, 施云东, 郭思捷, 贾天娇, 陈岩, 周佳妮, 车舒, authorCompany=null, correspAuthors=王宏光, authorNote=
作者贡献声明
陶丽莹负责论文课题设计，收集数据，分析资料，撰写论文；郭庆梅、庞崇、施云东、郭思捷、贾天娇、陈岩、周佳妮和车舒负责收集和整理数据；王宏光负责修改论文，指导撰写文章并最后定稿。
, correspAuthorsNote=
, copyrightStatement=
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10.1055/a-2665-7090., articleTitle=Double the efficacy, half the effort: Columnar transparent cap-assisted cholangioscopy for bile duct stone extraction, refAbstract=null)], funds=null, companyList=[AuthorCompany(id=1317885753930142035, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, xref=null, ext=[AuthorCompanyExt(id=1317885753938530644, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, companyId=1317885753930142035, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Gastroenterology，Jilin People’s Hospital，Jilin，Jilin 132001，China), AuthorCompanyExt(id=1317885753946919253, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, companyId=1317885753930142035, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=吉林市人民医院消化内科，吉林 吉林 132001)])], figs=[ArticleFig(id=1317885759068164496, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=EN, label=Figure 1, caption=
Intraoperative procedure of direct visualization electrohydraulic lithotripsy for giant common bile duct stones via peroral cholangiopancreatoscopy assisted by a conical transparent cap, figureFileSmall=gAtFBQJKYfx4xYlhgv/CZA==, figureFileBig=V8cD2gq6rGl4TdUoEARhhQ==, tableContent=null), ArticleFig(id=1317885759303045521, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=CN, label=图1, caption=
锥形透明帽辅助经口胆道镜直视液电治疗胆总管巨大结石手术过程注：a，术前超声内镜评估胆总管巨大结石直径及胆管宽度；b，十二指肠乳头插管；c，十二指肠乳头括约肌球囊扩张术；d，经口胆道镜插入胆管内直视观察胆总管巨大结石；e，经口胆道镜先端佩戴锥形透明帽；f，液电光纤位于锥形透明帽内，锥形透明帽远端固定结石，液电对准结石中心进行碎石；g，液电碎石后胆总管巨大结石被击碎；h，碎石取石后再次进入经口胆道镜观察胆管内无结石残留；i，导管内留置鼻胆管引流，十二指肠乳头上方应用和谐夹预防出血、穿孔。
, figureFileSmall=gAtFBQJKYfx4xYlhgv/CZA==, figureFileBig=V8cD2gq6rGl4TdUoEARhhQ==, tableContent=null), ArticleFig(id=1317885759730864530, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=EN, label=Table 1, caption=
Comparison of preoperative clinical data between the two groups
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） | 统计值 | P值 |
|---|
| 年龄（岁） | 69.87±14.20 | 76.20±12.63 | t=-1.825 | 0.073 |
| 性别［例（%）］ | | | χ2=1.071 | 0.301 |
| 男 | 14（46.67） | 18（60.00） | | |
| 女 | 16（53.33） | 12（40.00） | | |
| 高血压［例（%）］ | 11（36.67） | 14（46.67） | χ2=0.617 | 0.432 |
| WBC（×109/L） | 8.00（6.10～12.00） | 8.65（5.62～11.30） | Z=0.255 | 0.798 |
| CRP（mg/L） | 80.48（38.45～132.25） | 56.40（21.50～100.91） | Z=0.878 | 0.380 |
| TBil（μmol/L） | 47.60（25.55～103.72） | 58.30（27.80～91.00） | Z=0.094 | 0.925 |
| DBil（μmol/L） | 34.70（16.60～73.83） | 43.00（15.30～77.10） | Z=-0.028 | 0.977 |
| 结石直径（mm） | 17.32±3.01 | 15.83±4.03 | t=1.616 | 0.111 |
), ArticleFig(id=1317885759844110739, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=CN, label=表1, caption=
两组患者术前临床资料比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） | 统计值 | P值 |
|---|
| 年龄（岁） | 69.87±14.20 | 76.20±12.63 | t=-1.825 | 0.073 |
| 性别［例（%）］ | | | χ2=1.071 | 0.301 |
| 男 | 14（46.67） | 18（60.00） | | |
| 女 | 16（53.33） | 12（40.00） | | |
| 高血压［例（%）］ | 11（36.67） | 14（46.67） | χ2=0.617 | 0.432 |
| WBC（×109/L） | 8.00（6.10～12.00） | 8.65（5.62～11.30） | Z=0.255 | 0.798 |
| CRP（mg/L） | 80.48（38.45～132.25） | 56.40（21.50～100.91） | Z=0.878 | 0.380 |
| TBil（μmol/L） | 47.60（25.55～103.72） | 58.30（27.80～91.00） | Z=0.094 | 0.925 |
| DBil（μmol/L） | 34.70（16.60～73.83） | 43.00（15.30～77.10） | Z=-0.028 | 0.977 |
| 结石直径（mm） | 17.32±3.01 | 15.83±4.03 | t=1.616 | 0.111 |
), ArticleFig(id=1317885759927996820, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=EN, label=Table 2, caption=
Comparison of surgical-related indicators between the two groups
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） | 统计值 | P值 |
|---|
| 技术成功［例（%）］ | 18（60.00） | 25（83.33） | χ2=4.022 | 0.045 |
| 临床成功［例（%）］ | 30（100.00） | 30（100.00） | χ2=0.000 | >0.05 |
| ERCP操作时间（min） | 54.50（42.00～65.00） | 46.00（42.25～49.00） | Z=2.012 | 0.044 |
| 液电碎石时间（min） | 13.50（9.25～17.75） | 8.00（6.25～11.75） | Z=2.749 | 0.006 |
| ∆WBC（×109/L） | -1.20（-2.83～1.95） | 0.30（-2.35～1.60） | Z=-0.880 | 0.379 |
| ∆NEU（%） | 0.03（-0.06～0.15） | 0.05（0.00～0.12） | Z=-1.057 | 0.290 |
| ∆CRP（mg/L） | -27.79±65.89 | -12.92±52.86 | t=-0.805 | 0.425 |
| ∆TBil（μmol/L） | -40.60（-82.80～-13.45） | -43.10（-54.98～-17.50） | Z=-0.282 | 0.778 |
| ∆DBil（μmol/L） | -41.25±34.09 | -34.16±23.68 | t=-0.701 | 0.488 |
), ArticleFig(id=1317885760003494293, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=CN, label=表2, caption=
两组手术相关指标比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） | 统计值 | P值 |
|---|
| 技术成功［例（%）］ | 18（60.00） | 25（83.33） | χ2=4.022 | 0.045 |
| 临床成功［例（%）］ | 30（100.00） | 30（100.00） | χ2=0.000 | >0.05 |
| ERCP操作时间（min） | 54.50（42.00～65.00） | 46.00（42.25～49.00） | Z=2.012 | 0.044 |
| 液电碎石时间（min） | 13.50（9.25～17.75） | 8.00（6.25～11.75） | Z=2.749 | 0.006 |
| ∆WBC（×109/L） | -1.20（-2.83～1.95） | 0.30（-2.35～1.60） | Z=-0.880 | 0.379 |
| ∆NEU（%） | 0.03（-0.06～0.15） | 0.05（0.00～0.12） | Z=-1.057 | 0.290 |
| ∆CRP（mg/L） | -27.79±65.89 | -12.92±52.86 | t=-0.805 | 0.425 |
| ∆TBil（μmol/L） | -40.60（-82.80～-13.45） | -43.10（-54.98～-17.50） | Z=-0.282 | 0.778 |
| ∆DBil（μmol/L） | -41.25±34.09 | -34.16±23.68 | t=-0.701 | 0.488 |
), ArticleFig(id=1317885760129323414, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=EN, label=Table 3, caption=
Comparison of complications between the two groups
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） |
|---|
| 出血［例（%）］ | 0（0.00） | 1（3.33） |
| 胆管炎［例（%）］ | 3（10.00） | 0（0.00） |
| 穿孔［例（%）］ | 0（0.00） | 0（0.00） |
| 胰腺炎［例（%）］ | 7（23.33） | 4（13.33） |
| 胆管壁损伤［例（%）］ | 3（10.00） | 0（0.00） |
| 高淀粉酶血症［例（%）］ | 0（0.00） | 2（6.67） |
), ArticleFig(id=1317885760213209495, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885750264320332, language=CN, label=表3, caption=
两组并发症情况比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 项目 | 经口胆胰管镜直视液电碎石组（n=30） | 透明帽辅助经口胆胰管镜直视液电碎石组（n=30） |
|---|
| 出血［例（%）］ | 0（0.00） | 1（3.33） |
| 胆管炎［例（%）］ | 3（10.00） | 0（0.00） |
| 穿孔［例（%）］ | 0（0.00） | 0（0.00） |
| 胰腺炎［例（%）］ | 7（23.33） | 4（13.33） |
| 胆管壁损伤［例（%）］ | 3（10.00） | 0（0.00） |
| 高淀粉酶血症［例（%）］ | 0（0.00） | 2（6.67） |
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