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The Barcelona Clinic Liver Cancer (BCLC) system is a major international framework for hepatocellular carcinoma prognostic assessment and treatment decision-making. While preserving the overall architecture of the 2022 edition,the 2026 update integrates the latest research evidence in locoregional therapy,systemic therapy,and liver transplantation,emphasizes a direct correspondence between staging and evidence-based first-line treatment options,and highlights the refined assessment of liver function,individualized decision-making,and pathway optimization in complex scenarios. This article gives an excerpt of the core concepts,key definitions,and key points regarding first-line treatment options for different stages in the 2026 update,with brief comments on the clinical practice in China.
, authors=Jihua Xue
1, Qingfen Ye
2, Yinying Lu
3, authorsList=Jihua Xue, Qingfen Ye, Yinying Lu, authorCompany=null, correspAuthors=Yinying Lu, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317885700960273150, articleId=1317885700435985148, tenantId=1146029695717560320, journalId=1316781422847033486, language=CN, title=《巴塞罗那肝癌临床分期预后评估与治疗推荐策略:2026更新版》摘译, columnId=1317885688037618114, journalTitle=临床肝胆病杂志, columnName=指南与规范, runingTitle=null, highlight=null, articleAbstract=
巴塞罗那肝癌临床分期(BCLC分期)系统是肝细胞癌预后评估与治疗决策的重要国际框架。BCLC 2026版在保留2022版总体架构的基础上,整合了局部治疗、系统治疗及肝移植领域的最新研究证据,强调各分期与循证医学支持的首次治疗选择直接对应,突出肝功能精细评估、个体化决策及复杂情境下的路径优化。本文对BCLC 2026版的核心观念、关键定义及各阶段首次治疗选择要点进行摘译,并结合我国临床实践作简要评述。
, authors=薛继华
1, 叶庆芬
2, 陆荫英
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作者贡献声明
薛继华、叶庆芬负责翻译;陆荫英负责审校。薛继华与叶庆芬对本文贡献等同,同为第一作者。
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:本刊所有图片、文字及版式设计的版权归《临床肝胆病杂志》所有。本刊发表的原创性文章,如无特殊声明,《临床肝胆病杂志》保留任何形式的编辑、修改、出版、使用或授权使用权利。, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=6gRDwtxG7JC8b0qmy5MFjw==, magXml=jpvFNShv5cmlnr3GkTIUbQ==, pdfUrl=null, pdf=1FYA5g93OVGWV9pwEcfMiQ==, pdfFileSize=570593, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=74ViHmlwFWx9biG6UhcaTA==, mapNumber=null, fund=null)}, authors=[Author(id=1317885701446812425, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885700435985148, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1317885701711053579, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885700435985148, authorId=1317885701446812425, language=EN, stringName=Jihua Xue, firstName=Jihua, middleName=null, lastName=Xue, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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Reig M,
Sanduzzi-Zamparelli M,
Forner A,
et al. BCLC strategy for prognosis prediction and treatment recommendations: The 2026 update[J].
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10.1016/j.jhep.2025.10.020., articleTitle=BCLC strategy for prognosis prediction and treatment recommendations: The 2026 update, refAbstract=null), Reference(id=1317885705708225314, tenantId=1146029695717560320, journalId=1316781422847033486, articleId=1317885700435985148, doi=null, pmid=null, pmcid=null, year=2023, volume=31, issue=9, pageStart=910, pageEnd=920, url=null, language=null, rfNumber=2, rfOrder=1, authorNames=国家感染性疾病临床医学研究中心, 北京医学会肝病学分会, 中国老年学及老年医学学会转化医学分会, journalName=中华肝脏病杂志, refType=null, unstructuredReference=国家感染性疾病临床医学研究中心, 北京医学会肝病学分会, 中国老年学及老年医学学会转化医学分会. 晚期原发性肝癌精细化诊疗管理专家共识(2023年版)[J].
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