Article(id=1317885799308312882, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, articleNumber=null, orderNo=null, doi=10.12449/JCH260834, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1762876800000, receivedDateStr=2025-11-12, revisedDate=null, revisedDateStr=null, acceptedDate=1772380800000, acceptedDateStr=2026-03-02, onlineDate=1792138059688, onlineDateStr=2026-10-16, pubDate=1787587200000, pubDateStr=2026-08-25, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792138059688, onlineIssueDateStr=2026-10-16, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792138059688, creator=13701087609, updateTime=1792138059688, updator=13701087609, issue=Issue{id=1317885672153797495, tenantId=1146029695717560320, journalId=1316781422847033486, year='2026', volume='42', issue='8', pageStart='1745', pageEnd='2000', issueExtLink='null', onlineDate='null', pubDate='1787587200000', pubDateStr='2026-08-25', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792138029373, creator='13701087609', updateTime=1792138608261, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317888100290900262, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317888100290900263, tenantId=1146029695717560320, journalId=1316781422847033486, issueId=1317885672153797495, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1974, endPage=1979, ext={EN=ArticleExt(id=1317885799497056563, articleId=1317885799308312882, tenantId=1146029695717560320, journalId=1316781422847033486, language=EN, title=Pathogenesis and treatment of craniopharyngioma-related liver diseases, columnId=1317885737828205560, journalTitle=Journal of Clinical Hepatology, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

Patients with craniopharyngioma are at a high risk of developing metabolic dysfunction-associated fatty liver disease and its severe complications，yet this association is often neglected in clinical practice，with a lack of systematic reviews. This article systematically reviews the clinical spectrum and epidemiological characteristics of liver diseases associated with craniopharyngioma，with a focus on their core pathogenic mechanisms，and it also summarizes current tumor treatment strategies aimed at preventing hypothalamic injury and highlights that establishing a multidisciplinary collaborative diagnosis and treatment model and implementing early intervention are key to improving prognosis. Future research should focus on elucidating the precise pathways through which hypothalamic injury leads to metabolic disturbances，thereby facilitating the development of targeted therapies，in order to provide new directions for fundamentally improving the clinical outcomes of these patients.

, authors=Ye Cheng, Yin Zheng, Jie Qin, authorsList=Ye Cheng, Yin Zheng, Jie Qin, authorCompany=null, correspAuthors=Jie Qin, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317885802479206711, articleId=1317885799308312882, tenantId=1146029695717560320, journalId=1316781422847033486, language=CN, title=颅咽管瘤相关肝脏疾病的致病机制及治疗, columnId=1317885739623367674, journalTitle=临床肝胆病杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

颅咽管瘤患者是代谢相关脂肪性肝病及其严重并发症的高危人群，但这一关联在临床上常被忽视，相关系统性总结匮乏。本文系统回顾了颅咽管瘤相关肝脏疾病的临床谱系与流行病学特征，重点分析了其发病的核心机制，并总结了当前以预防下丘脑损伤为导向的肿瘤治疗策略，明确了建立多学科协作诊疗模式并实施早期干预是改善预后的关键。未来研究应致力于深入解析下丘脑损伤导致代谢紊乱的精确通路，并以此为基础开发靶向治疗，为从根本上改变此类患者的临床结局提供新方向。

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注：GH，生长激素；TSH，促甲状腺激素；ACTH，促肾上腺皮质激素；FSH，卵泡刺激素；LH，黄体生成素；MAFLD，代谢相关脂肪性肝病。

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