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随着年龄增长，机体往往同时出现慢性炎症、肌肉衰减、脂肪堆积、心脏功能下降和认知能力减退。过去研究多从单一器官或某类衰老细胞寻找原因，但不同器官为何会在相近时期共同衰退，仍缺乏统一解释。斯坦福大学研究团队在老年小鼠中发现，组织驻留巨噬细胞清除衰老中性粒细胞的能力下降，可能是推动全身多器官老化的重要环节。7月16日，相关研究成果发表于《Science》。

, authors=null, authorsList=null, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=版权所有，未经授权，不得转载。, copyrightOwner=《科技导报》编辑部, extLink=null, articleAbsUrl=null, sourceXml=pFYcX7FCQ9wGqVHzQRUozQ==, magXml=ZZ0SUxhBOK/CBkeJc2HGvw==, pdfUrl=null, pdf=CKyYaokCBKnUYHrLHmln9g==, pdfFileSize=1531411, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=hwlouojetKmEAQAzHQgRiw==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=J8gCNobcmHDNpw1YnkcazA==, mapNumber=null, fund=null)}, authors=null, keywords=null, refs=null, funds=null, companyList=null, figs=[ArticleFig(id=1296828805205742034, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1296827251664908844, language=EN, label=null, caption=null, figureFileSmall=Rd6MRcBhV0okaueF3YGhqQ==, figureFileBig=x6baH4w0yQ0BhpwkiPj+CA==, tableContent=null), ArticleFig(id=1296828805268656595, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1296827251664908844, language=CN, label=null, caption=组织驻留巨噬细胞承担清除衰老中性粒细胞的任务。随着年龄增长，其清除能力下降，可能导致衰老中性粒细胞积累并引发多器官慢性炎症

（图片来源：PRB ARTS/Adobe Stock）

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