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长期以来，嵌合抗原受体T细胞（antigen receptor t-cell immunotherapy，CAR-T）疗法虽在血液肿瘤治疗中屡创奇迹，但其高昂的成本与复杂的体外制造工艺却如同“达摩克利斯之剑”。传统的CAR-T需要将患者的T细胞提取出体外，在实验室进行数周的基因改造与扩增后再回输。这不仅导致每剂疗法售价高达数十万美元，长达3~6周的等待周期也让许多急重症患者失去了生存机会。

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（图片来源：杜克大学官网）

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