Article(id=1242141968378175511, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242141260123811886, articleNumber=null, orderNo=null, doi=10.3981/j.issn.1000-7857.2024.06.00629, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1711814400000, receivedDateStr=2024-03-31, revisedDate=1718899200000, revisedDateStr=2024-06-21, acceptedDate=null, acceptedDateStr=null, onlineDate=1735142400000, onlineDateStr=2024-12-26, pubDate=1732723200000, pubDateStr=2024-11-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1735142400000, onlineIssueDateStr=2024-12-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774079323140, creator=sys-migrate, updateTime=1774079323140, updator=sys-migrate, issue=Issue{id=1242141260123811886, tenantId=1146029695717560320, journalId=1146031591421210625, year='2024', volume='42', issue='22', pageStart='1', pageEnd='108', issueExtLink='null', onlineDate='null', pubDate='1732723200000', pubDateStr='2024-11-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=null, issueType=-1, specialIssue=null, createTime=1774079154279, creator='sys-migrate', updateTime=1774079154279, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=63, endPage=69, ext={EN=ArticleExt(id=1242141974698991697, articleId=1242141968378175511, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Protective mechanism of probiotic supplements on oxidative stress levels in high-level athletes, columnId=1242141965945479168, journalTitle=Science & Technology Review, columnName=Exclusive：Anti aging and health of the elderly, runingTitle=null, highlight=null, articleAbstract=Oxidative stress is an important mechanism of cell aging and injury, and extensive exercise can cause oxidative stress damage to cells of multiple systems/organs in body. Probiotic supplements have many biological functions, such as antioxidant and immune regulation. This study focuses on high-level athletes, aiming to clarify the protective effect of probiotic supplements on exercise-related oxidative stress damage, by analyzing the impact of probiotic supplements on oxidative stress, inflammation levels, and immune state. Oxidative stress indicators are serum malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH), and total antioxidant capacity (TAOC); Inflammatory markers include serum C-reactive protein (CRP) and tumor necrosis factor-α (TNF)-α, and the level of interleukin-6 (IL-6); Immune indicators include peripheral blood CD4+, CD8+, and CD4+CD25+T cell counts. The results showed that probiotic supplements can increase the levels of SOD, GSH, TAOC, CD4+CD25+T cell counts, and reduce the levels of MDA, TNF-α, CD4+, and CD8+ cell counts, indicating that probiotic supplements can improve the oxidative stress and inflammation caused by extensive exercise, and improve immune regulatory functions., authors=NING Fangtang¹, MA Guoqiang², WANG Yuru³, authorsList=NING Fangtang, MA Guoqiang, WANG Yuru, authorCompany=1. Shandong Provincial Water Sports Management Center, Rizhao 276800, China;
2. Shanghai Institute of Sports Science (Shanghai Anti-Doping Center), Shanghai 200030, China;
3. Sports Nutrition Branch of Chinese Nutrition Society, Beijing 100015, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242141974032097346, articleId=1242141968378175511, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=益生菌补充剂对高水平运动员氧化应激水平的保护机制, columnId=1242141965182116849, journalTitle=科技导报, columnName=专题：抗衰老与老年健康, runingTitle=null, highlight=null, articleAbstract=氧化应激是细胞衰老、损伤的重要机制，大量运动可导致人体多系统/器官细胞发生氧化应激损伤。益生菌补充剂具有抗氧化、免疫调节等生物功能。以高水平运动员为研究对象，通过分析益生菌补充剂对氧化应激、炎症水平及免疫状态的影响，旨在明确益生菌补充剂对运动相关的氧化应激损伤的保护作用。氧化应激指标包括血清丙二醛（MDA）、超氧化物歧化酶（SOD）、还原型谷胱甘肽（GSH）水平以及血清总抗氧化能力（TAOC）；炎症指标包括血清C-反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）和白细胞介素-6（IL-6）水平；免疫指标包括外周血CD4+、CD8+、CD4+CD25+T细胞计数。结果显示，益生菌补充剂可提高机体SOD、GSH、TAOC和CD4+CD25+T细胞计数水平，降低MDA、TNF-α水平、CD4+和CD8+细胞计数水平，说明益生菌补充剂可改善大量运动所致的氧化应激和炎症状态，具有免疫调节功能。, authors=宁方堂¹, 马国强², 王昱儒³, authorsList=宁方堂, 马国强, 王昱儒, authorCompany=1. 山东省水上运动管理中心, 日照 276800;
2. 上海体育科学研究所(上海市反兴奋剂中心), 上海 200030;
3. 中国营养学会运动营养分会, 北京 100015, correspAuthors=null, authorNote=宁方堂,主治医师,研究方向为运动医务监督,运动相关性疾病、运动损伤的营养补充剂干预,运动训练监控,电子信箱:ningfangtang@126.com;马国强(通信作者),研究员,研究方向为运动能力评定,训练监控,高原低氧训练等,电子信箱:maguoqiang1978@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=E/sUufmBXbDK6OVsxouekA==, pdfFileSize=734231, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1242141973461671981, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141968378175511, language=CN, orderNo=1, keyword=氧化应激), Keyword(id=1242141973537169454, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141968378175511, language=CN, orderNo=1, keyword=细胞损伤), 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