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身痛逐瘀汤质量标志物(Q-Marker)的预测分析
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科技导报 | 专题:中医临床研究的范式与应用 2024, 42(21): 139-148
身痛逐瘀汤质量标志物(Q-Marker)的预测分析
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杨云云1,2, 陈祁青3, 王建伟1, 马东2, 安德浩2, 王化省2, 朱宝3, 田广芳3
作者信息
    1. 延安市中医医院骨科, 延安 716000;
    2. 甘肃中医药大学中医临床学院, 兰州 730030;
    3. 甘肃省中医院, 兰州 730000
Predictive analysis of quality markers (Q-Marker) of shentong zhuyu decoction
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出版时间: 2024-11-13 doi: 10.3981/j.issn.1000-7857.2023.10.01578
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通过检索国内外数据库,以身痛逐瘀汤为主题,根据中药质量标志物“五原则”,对身痛逐瘀汤质量评价的潜在标志物进行综合预测分析,结果发现,羟基红花黄色素A、苦杏仁苷、阿魏酸、藁本内酯、洋川芎内脂A、洋川芎内脂I、绿原酸、龙胆苦苷、马钱苷酸、异欧前胡素、羌活醇、肌苷、槲皮素、山柰酚、苯甲酸、甘草酸、甘草素、甘草苷等成分可作为身痛逐瘀汤的质量标志物,进而为该方后续的质量控制、药效评价、现代化研究和国际化发展提供支持。
身痛逐瘀汤  /  化学成分  /  药理作用  /  质量标志物  /  经典名方
By searching domestic and international databases, with shetong zhuyu decoction as the theme, and according to the "five principles" of quality markers of traditional Chinese medicines, a comprehensive predictive analysis of potential markers for the quality evaluation of shetong zhuyu decoction was carried out, and it was found that hydroxy safflower yellow pigment A, amygdalin, ferulic acid, ligustilide, ligustilide, ligusticum lactone A, ligustilide I, chlorogenic acid, Gentianoside, strychnoside, isoeuropteroside, qiangwuol, inosine, quercetin, kaempferol, benzoic acid, glycyrrhizic acid, glycyrrhizin, glycyrrhizin, and so on can be used as the quality markers of shetong zhuyu decoction, which in turn can provide important support for the subsequent quality control, medicinal efficacy evaluation, modernization research, and internationalization development of this formula.
shetong zhuyu decoction  /  chemical composition  /  pharmacological effects  /  quality markers  /  classic prescriptions
杨云云, 陈祁青, 王建伟, 马东, 安德浩, 王化省, 朱宝, 田广芳. 身痛逐瘀汤质量标志物(Q-Marker)的预测分析. 科技导报, 2024 , 42 (21) : 139 -148 . DOI: 10.3981/j.issn.1000-7857.2023.10.01578
YANG Yunyun, CHEN Qiqing, WANG Jianwei, MA Dong, AN Dehao, WANG Huasheng, ZHU Bao, TIAN Guangfang. Predictive analysis of quality markers (Q-Marker) of shentong zhuyu decoction[J]. Science & Technology Review, 2024 , 42 (21) : 139 -148 . DOI: 10.3981/j.issn.1000-7857.2023.10.01578
2024年第42卷第21期
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doi: 10.3981/j.issn.1000-7857.2023.10.01578
  • 接收时间:2023-10-23
  • 首发时间:2024-12-14
  • 出版时间:2024-11-13
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  • 收稿日期:2023-10-23
  • 修回日期:2024-03-23
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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