Article(id=1242141943476593567, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242141088937485147, articleNumber=null, orderNo=null, doi=10.3981/j.issn.1000-7857.2024.05.00474, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1710259200000, receivedDateStr=2024-03-13, revisedDate=1720454400000, revisedDateStr=2024-07-09, acceptedDate=null, acceptedDateStr=null, onlineDate=1734105600000, onlineDateStr=2024-12-14, pubDate=1731427200000, pubDateStr=2024-11-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1734105600000, onlineIssueDateStr=2024-12-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774079317202, creator=sys-migrate, updateTime=1774079317202, updator=sys-migrate, issue=Issue{id=1242141088937485147, tenantId=1146029695717560320, journalId=1146031591421210625, year='2024', volume='42', issue='21', pageStart='1', pageEnd='188', issueExtLink='null', onlineDate='null', pubDate='1731427200000', pubDateStr='2024-11-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=null, issueType=-1, specialIssue=null, createTime=1774079113466, creator='sys-migrate', updateTime=1774079113466, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=87, endPage=93, ext={EN=ArticleExt(id=1242141947943530599, articleId=1242141943476593567, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine, columnId=1242141098387252106, journalTitle=Science & Technology Review, columnName=Exclusive: The paradigm and application of clinical research in traditional Chinese medicine, runingTitle=null, highlight=null, articleAbstract=When composite endpoints are used as efficacy indicators in clinical efficacy evaluation, the same weight is usually assigned to each indicator for overall evaluation.In fact, different indicators are often of different importances for patients, and a simple comprehensive analysis cannot reflect the important concept of "patient-centered".To address these issues, this article introduces an efficacy evaluation method based on patient preference analysis of composite endpoints.By integrating multidimensional indicators (such as clinical efficacy indicators, patient-reported outcomes) while considering each patient preference, this method ranks different indicators, assigns varying importances, and compares efficacies of interventions.It is concluded that this method is suitable for the evaluation of complex intervention in traditional Chinese medicine and is compatible with the holistic view and individual treatment, which can reflect the clinical reality and the real diagnosis and treatment environment, and embody the real value of treatment to patients.It is suggested that in the future, the traditional Chinese medicine researchers should apply this method in efficacy evaluation scenarios with multiple composite indicators, patient-reported outcomes and real world., authors=LI Shuangjing1 , YAN Shiyan1 , LU Ying2 , authorsList=LI Shuangjing, YAN Shiyan, LU Ying, authorCompany=1. College of Acupuncture and Massage, Beijing University of Chinese Medicine, Beijing 100010, China; 2. Department of Biomedical Data Science, Stanford University School of Medicine, California 94305, USA, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242141947322773589, articleId=1242141943476593567, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=基于患者偏好分析复合终点的疗效评价方法及其对中医的启示, columnId=1242141097774883713, journalTitle=科技导报, columnName=专题:中医临床研究的范式与应用, runingTitle=null, highlight=null, articleAbstract=综述了基于患者偏好分析复合终点的疗效评价方法,该方法可在整合多维指标(例如临床疗效指标、患者报告结局)的同时考虑每个患者的意见,按各指标对患者的重要性进行排序后比较干预措施的疗效。论述了此方法在中医领域的适用场景,认为此方法适用于中医复杂干预的评价,与中医药的整体观和个体化治疗相契合,能够回归中医临床实际并反映真实诊疗环境,体现治疗对患者的真正价值。建议未来中医领域研究者可在具有多个复合指标、患者报告结局和真实世界的中医疗效评价场景中应用此方法。, authors=李双婧1 , 闫世艳1 , 陆盈2 , authorsList=李双婧, 闫世艳, 陆盈, authorCompany=1. 北京中医药大学针灸推拿学院, 北京 100010; 2. 美国斯坦福大学医学院生物医学数据科学系, 美国加利福尼亚 94305, correspAuthors=null, authorNote=李双婧,博士研究生,研究方向为中医临床研究方法学,电子信箱:lshuangj19980810@163.com;闫世艳(通信作者),研究员,研究方向为中医临床研究方法学,电子信箱:yanshiyan@bucm.edu.cn;陆盈(共同通信作者),教授,研究方向为生物统计学,电子信箱:ylu1@stanford.edu, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=BC8iZ91maWc02ZFodHfuNg==, pdfFileSize=1007645, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1242141944990740548, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=CN, orderNo=1, keyword=患者偏好), Keyword(id=1242141945078820933, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=CN, orderNo=1, keyword=复合终点), Keyword(id=1242141945150124102, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=CN, orderNo=1, keyword=结果排序期望), Keyword(id=1242141945225621575, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=CN, orderNo=1, keyword=中医临床疗效评价), Keyword(id=1242141946743959625, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=CN, orderNo=1, keyword=真实世界研究), Keyword(id=1242141947440214105, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=EN, orderNo=1, keyword=patient preference), Keyword(id=1242141947545071707, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=EN, orderNo=1, keyword=composite endpoint), Keyword(id=1242141947633152094, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=EN, orderNo=1, keyword=desirability of outcome ranking), Keyword(id=1242141947717038176, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=EN, orderNo=1, keyword=evaluation of traditional Chinese medicine clinical efficacy), Keyword(id=1242141947792535651, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242141943476593567, language=EN, orderNo=1, keyword=real world study)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1125356956822126595, delFlag=0, nameCn=科技导报, nameEn=Science & Technology Review, nameHistory1=null, nameHistory2=null, issn=1000-7857, eissn=, cn=11-1421/N, coden=null, periodic=3, language=CN, oaType=0, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=wfghvu3bhh/dKxuZ+ucVHA==, journalPrice=null, startedYear=null, abbrevIsoEn=Sci Technol Rev, journalRemark=null, publicationField=null, createdTime=null, updatedTime=1774230116083, createdBy=null, updatedBy=13041195026, firstLetterCn=S, firstLetterEn=S, subjectCode=Natural Sciences, subjectName=自然科学, subjectCodeEn=Natural Sciences, subjectNameEn=null, picCn=wfghvu3bhh/dKxuZ+ucVHA==, picEn=yjSfclmpNm7ihn9NbTZ69g==, jcr=null, cjcr=null, exts=[JournalExt(id=1242774439910290156, language=CN, name=科技导报, nameHistory1=null, nameHistory2=null, managedBy=中国科学技术协会, sponsoredBy=中国科学技术协会, publishedBy=科技导报社, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/CN/home, createdTime=1774230116107, updatedTime=1774230116107, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/CN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.cast.org.cn/webm, submissionEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionReviewUrl=https://kjdbauthor.cast.org.cn/webm, submissionCeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionAeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, option={"copyright":""}), JournalExt(id=1242774439960621805, language=EN, name=Science & Technology Review, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/EN/home, createdTime=1774230116119, updatedTime=1774230116119, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/EN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionReviewUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionCeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionAeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, option={"copyright":""})], databaseList=null, tenantJournalId=1146031591421210625, websiteList=[Website(id=1146104741081231361, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/CN, language=CN, createTime=1751182263881, createBy=18614031015, updateTime=1751778001962, updateBy=18614031015, name=科技导报, tplId=1146099689490845704, title=科技导报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1148021146403992296, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=articleTextType, value=kx, createTime=1751639170504, updateTime=1751639170504, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146378826469, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=banner, value=null, createTime=1751639170498, updateTime=1751639170498, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146366243556, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1751639170495, updateTime=1751639170495, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146395603687, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic, createTime=1751639170502, updateTime=1751639170502, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146387215078, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1751639170500, updateTime=1751639170500, creator=18614031015, updator=18614031015)]), Website(id=1146105254833139715, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/EN, language=EN, createTime=1751182386363, createBy=18614031015, updateTime=1753500121937, updateBy=18614031015, name=科技导报, tplId=1146101810881728533, title=Science & Technology Review, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1155838567709528217, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=articleTextType, value=kx, createTime=1753502988984, updateTime=1753502988984, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567692750998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=banner, value=null, createTime=1753502988980, updateTime=1753502988980, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567688556693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1753502988979, updateTime=1753502988979, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567705333912, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic, createTime=1753502988983, updateTime=1753502988983, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567701139607, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1753502988982, updateTime=1753502988982, creator=18614031015, updator=18614031015)])], journalTitle=科技导报, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Science & Technology Review, journalPhotoCn=wfghvu3bhh/dKxuZ+ucVHA==, journalPhotoEn=yjSfclmpNm7ihn9NbTZ69g==, journalFirstLetter=S, journalRecommend=null, journalNew=null, journalCollection=1, jcrJf=null, cjcrJf=0.91, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=null, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2024.05.00474, detailUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/10.3981/j.issn.1000-7857.2024.05.00474, pdfUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/PDF/10.3981/j.issn.1000-7857.2024.05.00474, pdfUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/PDF/10.3981/j.issn.1000-7857.2024.05.00474, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1731427200000, fullTextJson=null, articleText=null, reference=null)
科技导报
| 专题:中医临床研究的范式与应用 2024, 42(21): 87-93
基于患者偏好分析复合终点的疗效评价方法及其对中医的启示
全屏
李双婧1 , 闫世艳1 , 陆盈2
作者信息
1. 北京中医药大学针灸推拿学院, 北京 100010; 2. 美国斯坦福大学医学院生物医学数据科学系, 美国加利福尼亚 94305
An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine
Affiliations
出版时间: 2024-11-13
doi: 10.3981/j.issn.1000-7857.2024.05.00474
文章导航
综述了基于患者偏好分析复合终点的疗效评价方法,该方法可在整合多维指标(例如临床疗效指标、患者报告结局)的同时考虑每个患者的意见,按各指标对患者的重要性进行排序后比较干预措施的疗效。论述了此方法在中医领域的适用场景,认为此方法适用于中医复杂干预的评价,与中医药的整体观和个体化治疗相契合,能够回归中医临床实际并反映真实诊疗环境,体现治疗对患者的真正价值。建议未来中医领域研究者可在具有多个复合指标、患者报告结局和真实世界的中医疗效评价场景中应用此方法。
患者偏好
/
复合终点
/
结果排序期望
/
中医临床疗效评价
/
真实世界研究
When composite endpoints are used as efficacy indicators in clinical efficacy evaluation, the same weight is usually assigned to each indicator for overall evaluation.In fact, different indicators are often of different importances for patients, and a simple comprehensive analysis cannot reflect the important concept of "patient-centered".To address these issues, this article introduces an efficacy evaluation method based on patient preference analysis of composite endpoints.By integrating multidimensional indicators (such as clinical efficacy indicators, patient-reported outcomes) while considering each patient preference, this method ranks different indicators, assigns varying importances, and compares efficacies of interventions.It is concluded that this method is suitable for the evaluation of complex intervention in traditional Chinese medicine and is compatible with the holistic view and individual treatment, which can reflect the clinical reality and the real diagnosis and treatment environment, and embody the real value of treatment to patients.It is suggested that in the future, the traditional Chinese medicine researchers should apply this method in efficacy evaluation scenarios with multiple composite indicators, patient-reported outcomes and real world.
patient preference
/
composite endpoint
/
desirability of outcome ranking
/
evaluation of traditional Chinese medicine clinical efficacy
/
real world study
李双婧, 闫世艳, 陆盈.
基于患者偏好分析复合终点的疗效评价方法及其对中医的启示.
科技导报,
2024
, 42
(21)
: 87
-93
.
DOI: 10.3981/j.issn.1000-7857.2024.05.00474
LI Shuangjing, YAN Shiyan, LU Ying.
An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine[J].
Science & Technology Review ,
2024
, 42
(21)
: 87
-93
.
DOI: 10.3981/j.issn.1000-7857.2024.05.00474
2024年第42卷第21期
PDF下载
277
66
引用本文
BibTeX
文章信息
doi: 10.3981/j.issn.1000-7857.2024.05.00474
接收时间:2024-03-13
首发时间:2024-12-14
出版时间:2024-11-13
收稿日期:2024-03-13
修回日期:2024-07-09
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2024.05.00474
复制链接
引用本文
BibTeX
2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
关闭全屏
BibTeX
EndNote
RefWorks
TxT