Article(id=1242141642350731964, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242141088937485147, articleNumber=null, orderNo=null, doi=10.3981/j.issn.1000-7857.2024.05.00476, pmid=null, cstr=null, oa=1, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1710691200000, receivedDateStr=2024-03-18, revisedDate=1726070400000, revisedDateStr=2024-09-12, acceptedDate=null, acceptedDateStr=null, onlineDate=1730217600000, onlineDateStr=2024-10-30, pubDate=1731427200000, pubDateStr=2024-11-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1730217600000, onlineIssueDateStr=2024-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=1730217600000, onlineFirstDateStr=2024-10-30, sourceXml=null, magXml=null, createTime=1774079245410, creator=sys-migrate, updateTime=1774079245410, updator=sys-migrate, issue=Issue{id=1242141088937485147, tenantId=1146029695717560320, journalId=1146031591421210625, year='2024', volume='42', issue='21', pageStart='1', pageEnd='188', issueExtLink='null', onlineDate='null', pubDate='1731427200000', pubDateStr='2024-11-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=null, issueType=-1, specialIssue=null, createTime=1774079113466, creator='sys-migrate', updateTime=1774079113466, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=132, endPage=138, ext={EN=ArticleExt(id=1242141648168231660, articleId=1242141642350731964, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=A queue study on prevention of chemotherapy-induced myelosuppression in solid tumor patients using qi-invigorating and blood-nourishing therapy, columnId=1242141098387252106, journalTitle=Science & Technology Review, columnName=Exclusive: The paradigm and application of clinical research in traditional Chinese medicine, runingTitle=null, highlight=null, articleAbstract=Myelosuppression is one of the most common adverse reactions of chemotherapy, which leads to dose reduction, delays, or even interruptions of the treatment.This study adopted a prospective cohort design to collect data from chemotherapynaive patients with solid tumors.Patients were divided into two groups based on whether they continuously used Qi-invigorating and blood-nourishing traditional Chinese medicine (TCM) formulas for at least four cycles during the chemotherapy.The incidence rates of myelosuppression were compared between the two groups.Results showed that the incidence rates of grade 3~ 4 neutropenia, grade 2 or higher thrombocytopenia, and grade 2 or higher anemia were significantly lower in the exposure group compared to the non-exposure group, with all differences being statistically significant (P<0.001, P=0.002, P=0.007, respectively).The study demonstrated that the concurrent use of TCM formulas and patent medicines based on the principles of Qi-invigorating and blood-nourishing during chemotherapy can significantly reduce the incidence of myelosuppression.Qiinvigorating and blood-nourishing therapy can be used as a preventive measure for chemotherapy-induced myelosuppression in solid tumors, applied simultaneously with chemotherapy as a preventive strategy based on syndrome differentiation., authors=HE Wenting¹, ZUO Sen², XUAN Yanhong¹, ZHANG Hongliang¹, HU Lan¹, ZHANG Tong³, authorsList=HE Wenting, ZUO Sen, XUAN Yanhong, ZHANG Hongliang, HU Lan, ZHANG Tong, authorCompany=1. Department of Oncology, Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital, Urumqi 830000, China;
2. Fourth Clinical Medical College, Xinjiang Medical University, Urumqi 830000, China;
3. Department of Oncology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242141646108831969, articleId=1242141642350731964, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=益气养血法预防实体瘤化疗所致骨髓抑制的队列研究, columnId=1242141097774883713, journalTitle=科技导报, columnName=专题：中医临床研究的范式与应用, runingTitle=null, highlight=null, articleAbstract=采用前瞻性队列研究，收集初治的实体瘤化疗患者，将“是否在化疗期间连续至少4周期联合益气养血类中药”作为暴露因素分为2组，比较骨髓抑制发生率。结果显示，暴露组3~4级中性粒细胞减少、2级及以上血小板减少、2级及以上贫血的发生率明显低于非暴露组，差异均有统计学意义（P<0.001、P=0.002、P=0.007）。研究结果证明，化疗期间联合使用益气养血法为治则的汤剂、中成药可显著降低骨髓抑制的发生率。益气养血法可作为实体瘤化疗所致骨髓抑制的预防措施，在辨证论治的基础上前移至预防阶段与化疗同步使用。, authors=何文婷¹, 左森², 轩艳红¹, 张洪亮¹, 胡兰¹, 张彤³, authorsList=何文婷, 左森, 轩艳红, 张洪亮, 胡兰, 张彤, authorCompany=1. 新疆维吾尔自治区中医医院肿瘤二科, 乌鲁木齐 830000;
2. 新疆医科大学第四临床医学院, 乌鲁木齐 830000;
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