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2. Medical School, Guizhou University, Guiyang 550025, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242140894506328152, articleId=1242140886268719797, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=2023年生命科学热点回眸, columnId=1242140876735063025, journalTitle=科技导报, columnName=专题：2023年科技热点回眸, runingTitle=null, highlight=null, articleAbstract=2023年,生命科学多个领域的研究取得突破性进展。重点回顾其中一部分已经、正在和未来非常可能改变人类对生命科学研究的前沿热点:人工智能正越来越成为生命科学和医学应用的有力且重要工具;基于GLP-1激动剂的出现和空前的广泛应用;相分离、体外胚胎模型、神经科学、发育生物学等领域新的技术的进一步优化和应用;针对β-淀粉样蛋白的抗体疗法、干细胞及免疫疗法、mRNA疫苗、CRISPR基因编辑疗法等新的临床治疗手段的出现和初步临床应用。这些研究进展不但进一步拓展人类对生命本质奥秘的理解,也正在为阿尔兹海默症、肿瘤、病毒感染等一系列重大人类疾病的患者带来福音。, authors=张文阳¹, 杨昱鸽¹, 朱恒乐¹, 朱芳², 王呈呈², 胡荣贵^1,2, authorsList=张文阳, 杨昱鸽, 朱恒乐, 朱芳, 王呈呈, 胡荣贵, authorCompany=1. 中国科学院大学分子细胞科学卓越创新研究中心, 上海 200032;
2. 贵州大学医学院, 贵阳 550025, correspAuthors=null, authorNote=张文阳,硕士研究生,研究方向为蛋白质稳态与蛋白质降解调控与分子识别,电子信箱:zhangwenyang2022@sibcb.ac.cn;杨昱鸽（共同第一作者）,硕士研究生,研究方向为蛋白质稳态与蛋白质降解调控与分子识别,电子信箱:yangyuge2021@sibcb.ac.cn;朱恒乐（共同第一作者）,硕士研究生,研究方向为蛋白质降解调控与分子识别,电子信箱:zhuhengle2023@sibcb.ac.cn, correspAuthorsNote=王呈呈（共同通信作者）,讲师,研究方向为肿瘤药理学,电子信箱:ccwang@gzu.edu.cn;胡荣贵（通信作者）,研究员,研究方向为蛋白质降解调控与分子识别,电子信箱:coryhu@sibcb.ac.cn, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=QXNNz7E5+n2Lr7QLTGFTTQ==, pdfFileSize=6550685, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=科学技术部脑科学重大项目科技创新2030(2021ZD0203900)；贵州省科技计划项目(黔科合基础项目[2020]1Y086)；贵州省卫健委科学技术基金项目(gzwkj2022-219)；国家自然科学基金项目(92253302))}, authors=null, keywords=[Keyword(id=1242140893893959761, tenantId=1146029695717560320, 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