Article(id=1242140721545818118, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242140702436570024, articleNumber=null, orderNo=12, doi=10.3981/j.issn.1000-7857.2023.20.010, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1669996800000, receivedDateStr=2022-12-03, revisedDate=1680019200000, revisedDateStr=2023-03-29, acceptedDate=null, acceptedDateStr=null, onlineDate=1699249897020, onlineDateStr=2023-11-06, pubDate=1698422400000, pubDateStr=2023-10-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1699249897020, onlineIssueDateStr=2023-11-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774079025871, creator=sys-migrate, updateTime=1774079025871, updator=sys-migrate, issue=Issue{id=1242140702436570024, tenantId=1146029695717560320, journalId=1146031591421210625, year='2023', volume='41', issue='20', pageStart='1', pageEnd='112', issueExtLink='null', onlineDate='null', pubDate='1698422400000', pubDateStr='2023-10-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774079021316, creator='sys-migrate', updateTime=1774079021316, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=89, endPage=96, ext={EN=ArticleExt(id=1242140726050500639, articleId=1242140721545818118, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Advances in new diagnosis and current treatment of idiopathic central precocious puberty with Western medicine and Traditional Chinese medicine, columnId=1242116810380743325, journalTitle=Science & Technology Review, columnName=Reviews, runingTitle=null, highlight=null, articleAbstract=Children's health is a key concern in China at present. The incidence rate of precocious puberty in China is 2%, which is an important disease threatening children's physical and mental health. Idiopathic central precocious puberty (ICPP) is the most common type. This article reviews the current clinical research status, latest achievements, and cutting-edge trends of ICPP. The latest“Expert Consensus on Diagnosis and Treatment of Central Sexual Precocity (2022)”up-dates the age limit of central sexual precocity from 8 to 7.5 years old. Gene diagnosis is a new method to assist in the diagnosis of ICPP, and the“2022 Consensus”suggests that children with the family history of precocious puberty should undergo gene testing. GnRH agonists (GnRHa) are the gold standard treatment regimen for ICPP, which are beneficial for inhibiting bone age development, increasing the final adult height of children, reducing body mass index, and improving brain function. The traditional Chinese medicine treatment of ICPP is currently a research hotspot, including traditional Chinese medicine internal treatment, as well as external treatment methods such as ear acupoint pressing and massage, it has a significant therapeutic effect on ICPP, with its efficacy superior to GnRHa, and its safety may be better. Traditional Chinese medicine or a combination of traditional Chinese and Western medicine is expected to become a cutting-edge treatment option for ICPP., authors=DING Yicheng^1,2, WANG Hai^2*, BAO Mulong³, GU Shengnan¹, authorsList=DING Yicheng, WANG Hai, BAO Mulong, GU Shengnan, authorCompany=1. Graduate School, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China
2. Department of Pediatrics, the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China
3. Department of Massage, the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150001, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=qrHQb5PkkQyqtzr3zGSFVg==, pdfFileSize=570958, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242140725035475360, articleId=1242140721545818118, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=儿童特发性中枢性性早熟的新型诊断及中西医治疗进展, columnId=1242134377686180284, journalTitle=科技导报, columnName=综述, runingTitle=null, highlight=null, articleAbstract=儿童健康是中国现阶段重点关注的问题。中国性早熟发病率为2%，是威胁儿童身心健康的重要疾病，特发性中枢性性早熟（ICPP）为最常见类型。综述了 ICPP 的临床研究现状、最新成果，及前沿趋势。最新《中枢性性早熟诊断与治疗专家共识（2022）》将中枢性性早熟的年龄界限由 8岁提至 7.5岁，基因诊断方法是辅助诊断 ICPP的新方法，建议对有性早熟家族史的患儿进行基因检测。GnRH 激动剂（GnRHa）是 ICPP 的金标准治疗方案，有利于抑制骨龄发育、增加患儿的最终成年身高，降低身体质量指数，改善脑功能等。ICPP的中医治疗是现阶段的研究热点，包括中药内治法，及耳穴贴压法、推拿法等外治法，中药治疗ICPP的疗效优于 GnRHa，安全性可能更佳。中医或中西医结合联合有望成为 ICPP 的有效治疗方案。, authors=丁一诚^1,2，王海^2*，包木龙³，谷胜男¹, authorsList=丁一诚，王海，包木龙，谷胜男, authorCompany=1. 黑龙江中医药大学研究生院，哈尔滨 150040
2. 黑龙江中医药大学附属第一医院儿科，哈尔滨 150040
3. 黑龙江中医药大学附属第二医院推拿科，哈尔滨 150001, correspAuthors=null, authorNote=丁一诚，博士研究生，研究方向为中医药调治小儿常见病，电子信箱：dingyicheng2022@126.com, correspAuthorsNote=王海（通信作者），主任医师，研究方向为中医药调治小儿常见病，电子信箱：782955547@qq.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=nm941HShf8Y/g7nPf1G7qA==, pdfFileSize=570958, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=黑龙江中医药大学科研基金项目（2019XY05）)}, authors=null, keywords=[Keyword(id=1242140724540547479, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242140721545818118, language=CN, orderNo=1, keyword=儿童健康), Keyword(id=1242140724607656344, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242140721545818118, language=CN, orderNo=1, keyword=特发性中枢性性早熟), 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