Article(id=1242139768096633619, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242139740464554308, articleNumber=null, orderNo=16, doi=10.3981/j.issn.1000-7857.2022.05.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1590681600000, receivedDateStr=2020-05-29, revisedDate=1638892800000, revisedDateStr=2021-12-08, acceptedDate=null, acceptedDateStr=null, onlineDate=1650416212137, onlineDateStr=2022-04-20, pubDate=1647100800000, pubDateStr=2022-03-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1650416212137, onlineIssueDateStr=2022-04-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774078798551, creator=sys-migrate, updateTime=1774078798551, updator=sys-migrate, issue=Issue{id=1242139740464554308, tenantId=1146029695717560320, journalId=1146031591421210625, year='2022', volume='40', issue='5', pageStart='1', pageEnd='148', issueExtLink='null', onlineDate='null', pubDate='1647100800000', pubDateStr='2022-03-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774078791964, creator='sys-migrate', updateTime=1774078791964, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=122, endPage=131, ext={EN=ArticleExt(id=1242139770915205925, articleId=1242139768096633619, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Development status quo and applications of focused ultrasound in the treatment of brain diseases, columnId=1150494644690366681, journalTitle=Science & Technology Review, columnName=Papers, runingTitle=null, highlight=null, articleAbstract=The incidence of neurological diseases is increasing year by year, which seriously threatens human health and life. Ultrasound has been gradually applied to the treatment of brain diseases due to its non-invasiveness, high spatial resolution, mutiple stimulation targets, good MR compatibility effect and less adverse reactions. At present, the treatment of ultrasound neurological diseases mainly includes high-intensity focused ultrasound thermally lethal disease tissue, mechanical vibration to dissolve thrombus and low-intensity focused ultrasound stimulation therapy. This article briefly describes the development status of high-intensity focused ultrasound and its clinical applications in brain tumors, neuropathic pain, tremor, Parkinson, obsessivecompulsive disorder and stroke, as well as the development status of low-intensity focused ultrasound and its clinical applications in depression and epilepsy. Transcranial focused ultrasound can be used to treat neurological diseases noninvasively, but the impact of the skull needs to be fully considered., authors=ZHANG Yanqiu, JIAN Xiqi, authorsList=ZHANG Yanqiu, JIAN Xiqi, authorCompany=School of Biomedical Engineering & Technology, Tianjin Medical University, Tianjin 300070, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=cJYUMzqCJnIOx+d0HjYaAg==, pdfFileSize=569814, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242139770118288154, articleId=1242139768096633619, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=聚焦超声治疗脑部疾病的现状与应用, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=超声治疗具有非侵入性、空间分辨率高、刺激靶点多等特点，其磁共振兼容效果良好，不良反应较少，逐渐应用于脑部疾病的治疗。综述了超声应用于治疗神经系统疾病的2种主要类型：高强度聚焦超声治疗和低强度聚焦超声刺激治疗。目前，高强度聚焦超声在治疗脑肿瘤、神经性疼痛、震颤、帕金森、强迫症和脑中风等疾病领域具有广泛的临床应用；低强度聚焦超声刺激在治疗抑郁症和癫痫等疾病方面具有临床应用。经颅精准聚焦的聚焦超声可非侵入性治疗神经系统疾病，有望成为治疗脑部疾病新的临床手段。, authors=张艳秋, 菅喜岐, authorsList=张艳秋, 菅喜岐, authorCompany=天津医科大学生物医学工程与技术学院, 天津 300070, correspAuthors=null, authorNote=张艳秋，博士研究生，研究方向为医学超声，电子信箱：zyq_tmu@126.com, correspAuthorsNote=菅喜岐（通信作者），教授，研究方向为医学超声，电子信箱：jianxiqi@tmu.edu.cn, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=LrvdfxSSR4Aa/Ly+J4aidw==, pdfFileSize=569814, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=[Author(id=1278530598788632578, 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