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埃马纽埃尔·卡彭蒂耶、珍妮弗·杜德纳:因CRISPR/Cas9“基因剪刀”而获2020年诺贝尔化学奖的两位女科学家
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科技导报 | 科技人文 2021,39(20): 142-148
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科技导报 |科技人文 2021 , 39 (20) : 142 -148
埃马纽埃尔·卡彭蒂耶、珍妮弗·杜德纳:因CRISPR/Cas9“基因剪刀”而获2020年诺贝尔化学奖的两位女科学家
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陈彪, 付小航, 朱玥玮, 狄雨萌, 吴又进
作者信息
    中国科学技术大学科技史与科技考古系, 合肥 230026
通讯作者:
吴又进(通信作者),副研究员,研究方向为科技史、科技考古,电子信箱:yjwu@ustc.edu.cn
作者简介:
陈彪,副教授,研究方向为科技史、科技考古,电子信箱:chenbiao@ustc.edu.cn
Emmanuelle Marie Charpentier and Jennifer Anne Doudna: Two female scientists who were awarded the Nobel Prize in Chemistry 2020 for ‘gene scissors’
  • CHEN Biao, FU Xiaohang, ZHU Yuewei, DI Yumeng, WU Youjin
  • Affiliations
      Department of History of Science and Scientific Archaeology, University of Science and Technology of China, Hefei 230026, China
    出版时间: 2021-10-28 doi: 10.3981/j.issn.1000-7857.2021.20.014
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    埃马纽埃尔·卡彭蒂耶和珍妮弗·杜德纳,因合作开发基因编辑技术——CRISPR/Cas9“基因剪刀”而获得2020年诺贝尔化学奖。CRISPR/Cas9技术的低成本、强易用性和高效率,促进了生命科学的突破性发展,也使它拥有了巨大的商业价值。通过回顾两位科学家的科研历程和基因编辑领域的成就,提出了相关的思考和启示。
    2020年诺贝尔化学奖  /  基因编辑  /  CRISPR/Cas9技术
    Emmanuelle Marie Charpentier and Jennifer Anne Doudna were awarded the Nobel Prize in Chemistry 2020. The CRISPR/Cas9 gene editing technology, the "gene scissors", was jointly developed by the two female scientists. Due to its low cost and high ease, the CRISPR/Cas9 technology greatly promotes the development of the life sciences. The huge commercial value of this technology is also recognized by the society. This paper reviews the scientific researches of the two scientists, as well as the impact and the enlightenment of their results.
    the Nobel Prize in Chemistry 2020  /  gene editing  /  CRISPR/Cas9
    陈彪, 付小航, 朱玥玮, 狄雨萌, 吴又进. 埃马纽埃尔·卡彭蒂耶、珍妮弗·杜德纳:因CRISPR/Cas9“基因剪刀”而获2020年诺贝尔化学奖的两位女科学家. 科技导报, 2021 , 39 (20) : 142 -148 . DOI: 10.3981/j.issn.1000-7857.2021.20.014
    CHEN Biao, FU Xiaohang, ZHU Yuewei, DI Yumeng, WU Youjin. Emmanuelle Marie Charpentier and Jennifer Anne Doudna: Two female scientists who were awarded the Nobel Prize in Chemistry 2020 for ‘gene scissors’[J]. Science & Technology Review, 2021 , 39 (20) : 142 -148 . DOI: 10.3981/j.issn.1000-7857.2021.20.014

      安徽省高等学校省级质量工程项目(2019jyxm0014,2014jyxm015);中国科学技术大学校级教学研究项目(2018jyy13,2021ycjg12,2020kcsz062)

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    doi: 10.3981/j.issn.1000-7857.2021.20.014
    • 接收时间:2020-11-25
    • 首发时间:2021-11-08
    • 出版时间:2021-10-28
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    • 收稿日期:2020-11-25
    • 修回日期:2021-09-06
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    吴又进(通信作者),副研究员,研究方向为科技史、科技考古,电子信箱:yjwu@ustc.edu.cn
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    2种不同金属材料的力学参数

    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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