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近视巩膜生物力学研究进展
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科技导报 | 专题论文 2018,36(13): 39-43
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科技导报 | 专题论文 2018, 36(13): 39-43
近视巩膜生物力学研究进展
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周清怡, 赵斐, 周翔天
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    温州医科大学附属眼视光医院, 温州 325027

通讯作者:

周翔天(通信作者),研究员,研究方向为近视发病机制,电子信箱:zxt-dr@wz.zj.cn
Research advances in scleral biomechanics in myopia progression
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出版时间: 2018-07-13 doi: 10.3981/j.issn.1000-7857.2018.13.005
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近视是一种最为常见的具有致盲可能性的眼部疾患,其发病机制目前尚不完全明晰。巩膜可直接决定眼轴的长度,是近视形成的最终效应器。本文以巩膜为切入点,综述近视发生时巩膜组织生物力学性质的变化、相应巩膜组织成分的改变与原因,以及目前临床上针对性的近视治疗方案,展望了该研究领域的发展方向和趋势。
近视  /  巩膜生物力学  /  巩膜重塑  /  胶原  /  成纤维细胞
The increased prevalence of myopia and its potentially irreversible vison impairment have caused widespread concern, but the detailed pathogenesis of this disease needs further investigation. Experimental and clinical evidences indicate that excessive ocular elongation associated with myopia is the result of altered scleral shell. This review summarizes the research advances in scleral biomechanics in myopia progression, including biomechanical properties of the sclera in myopic eyes, the related changes and reasons of the composition of the scleral extracellular matrix, and some new clinical treatments. Future research direction and trend in this field are prospected as well.
myopia  /  scleral biomechanics  /  sclera remodeling  /  type I collagen  /  fibroblast
周清怡, 赵斐, 周翔天. 近视巩膜生物力学研究进展. 科技导报, 2018 , 36 (13) : 39 -43 . DOI: 10.3981/j.issn.1000-7857.2018.13.005
ZHOU Qingyi, ZHAO Fei, ZHOU Xiangtian. Research advances in scleral biomechanics in myopia progression[J]. Science & Technology Review, 2018 , 36 (13) : 39 -43 . DOI: 10.3981/j.issn.1000-7857.2018.13.005
2018年第36卷第13期
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doi: 10.3981/j.issn.1000-7857.2018.13.005
  • 接收时间:2018-05-08
  • 首发时间:2018-07-23
  • 出版时间:2018-07-13
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  • 收稿日期:2018-05-08
  • 修回日期:2018-06-11
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周翔天(通信作者),研究员,研究方向为近视发病机制,电子信箱:zxt-dr@wz.zj.cn
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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