Article(id=1242136725917610859, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242136723661075299, articleNumber=null, orderNo=5, doi=10.3981/j.issn.1000-7857.2018.05.003, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1518192000000, receivedDateStr=2018-02-10, revisedDate=1520611200000, revisedDateStr=2018-03-10, acceptedDate=null, acceptedDateStr=null, onlineDate=1522227366120, onlineDateStr=2018-03-28, pubDate=1520870400000, pubDateStr=2018-03-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1522227366120, onlineIssueDateStr=2018-03-28, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774078073239, creator=sys-migrate, updateTime=1774078073239, updator=sys-migrate, issue=Issue{id=1242136723661075299, tenantId=1146029695717560320, journalId=1146031591421210625, year='2018', volume='36', issue='5', pageStart='1', pageEnd='108', issueExtLink='null', onlineDate='null', pubDate='1520870400000', pubDateStr='2018-03-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774078072701, creator='sys-migrate', updateTime=1774078072701, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=23, endPage=27, ext={EN=ArticleExt(id=1242136728757154683, articleId=1242136725917610859, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Why first breakthrough of Monkeys cloned is in China, columnId=1242136588948418926, journalTitle=Science & Technology Review, columnName=Scientifc Comments, runingTitle=null, highlight=null, articleAbstract=Scientists in China have produced the first cloned primates by a technique similar to the one used to clone Dolly the sheep and nearly two dozen other species. The breakthrough was published in Cell on 25 January. This review described the techniques process and a brief history of cloning animal. The history failed to produce live primates until now. The group of Sun Qiang optimized reprogramming developed by other groups. One trick was to undo chemical modifications in the DNA that occur when embryonic cells turn into specialized cells. The success of cloned monkey offer some significant advantages to study human neuropathy model. More Labs are needed to promote the optimization of the technology., authors=PAN Dengke1,2, authorsList=PAN Dengke, authorCompany=1. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Institute of Organ Transplantation, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, Chengdu 610072, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=1xBGqYGjuAqzPhAAhYvHtg==, pdfFileSize=1575657, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242136727851180947, articleId=1242136725917610859, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=克隆猴在中国率先突破,到底靠的是什么?, columnId=1242121168237429742, journalTitle=科技导报, columnName=科技纵横, runingTitle=null, highlight=null, articleAbstract=中国科学家孙强研究团队利用类似克隆羊多莉的体细胞克隆技术,在国际上率先获得了克隆猴的成功,这一成果于2018年1月25日发表在《Cell》上。本文回顾了克隆猴的技术流程和难点、体细胞克隆动物简史及国内外克隆猴不成功的历史,点评了克隆猴成功的关键和意义,指出需要更多的实验室来推动该技术的优化。, authors=潘登科1,2, authorsList=潘登科, authorCompany=1. 中国农业科学院北京畜牧兽医研究所, 北京 100193;
2. 四川省医学科学院四川省人民医院器官移植研究所, 成都 610072, correspAuthors=null, authorNote=潘登科,副研究员,研究方向为体细胞克隆、基因敲除克隆等,电子信箱:pandengke2002@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=R1LYe+lgaKAXsdTfDj6QuQ==, pdfFileSize=1575657, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=国家重点基础研究发展计划(973计划)项目(2015CB554103))}, authors=null, keywords=[Keyword(id=1242136727570162575, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=CN, orderNo=1, keyword=克隆动物), Keyword(id=1242136727645660049, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=CN, orderNo=1, keyword=克隆猴), Keyword(id=1242136727712768914, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=CN, orderNo=1, keyword=体细胞核移植), Keyword(id=1242136728421610357, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=EN, orderNo=1, keyword=cloned animal), Keyword(id=1242136728497107830, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=EN, orderNo=1, keyword=cloned monkey), Keyword(id=1242136728568411000, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242136725917610859, language=EN, orderNo=1, keyword=somatic cell nuclear transfer)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1125356956822126595, delFlag=0, nameCn=科技导报, nameEn=Science & Technology Review, nameHistory1=null, nameHistory2=null, issn=1000-7857, eissn=, cn=11-1421/N, coden=null, periodic=3, language=CN, oaType=0, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=wfghvu3bhh/dKxuZ+ucVHA==, journalPrice=null, startedYear=null, abbrevIsoEn=Sci Technol Rev, journalRemark=null, publicationField=null, createdTime=null, updatedTime=1784015846012, createdBy=null, updatedBy=13041195026, firstLetterCn=K, firstLetterEn=K, subjectCode=Natural Sciences, subjectName=自然科学, subjectCodeEn=Natural Sciences, subjectNameEn=null, picCn=wfghvu3bhh/dKxuZ+ucVHA==, picEn=yjSfclmpNm7ihn9NbTZ69g==, jcr=null, cjcr=null, exts=[JournalExt(id=1283818766098219763, language=CN, name=科技导报, nameHistory1=null, nameHistory2=null, managedBy=中国科学技术协会, sponsoredBy=中国科学技术协会, publishedBy=科技导报社, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/CN/home, createdTime=1784015846037, updatedTime=1784015846037, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/CN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.cast.org.cn/webm, submissionEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionReviewUrl=https://kjdbauthor.cast.org.cn/webm, submissionCeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionAeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, option={"copyright":""}), JournalExt(id=1283818766144357108, language=EN, name=Science & Technology Review, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/EN/home, createdTime=1784015846048, updatedTime=1784015846048, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/EN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionReviewUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionCeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionAeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, option={"copyright":""})], databaseList=null, tenantJournalId=1146031591421210625, websiteList=[Website(id=1146104741081231361, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/CN, language=CN, createTime=1751182263881, createBy=18614031015, updateTime=1751778001962, updateBy=18614031015, name=科技导报, tplId=1146099689490845704, title=科技导报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1148021146403992296, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=articleTextType, value=kx, createTime=1751639170504, updateTime=1751639170504, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146378826469, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=banner, value=null, createTime=1751639170498, updateTime=1751639170498, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146366243556, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1751639170495, updateTime=1751639170495, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146395603687, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic, createTime=1751639170502, updateTime=1751639170502, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146387215078, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1751639170500, updateTime=1751639170500, creator=18614031015, updator=18614031015)]), Website(id=1146105254833139715, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/EN, language=EN, createTime=1751182386363, createBy=18614031015, updateTime=1753500121937, updateBy=18614031015, name=科技导报, tplId=1146101810881728533, title=Science & Technology Review, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1155838567709528217, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=articleTextType, value=kx, createTime=1753502988984, updateTime=1753502988984, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567692750998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=banner, value=null, createTime=1753502988980, updateTime=1753502988980, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567688556693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1753502988979, updateTime=1753502988979, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567705333912, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic, createTime=1753502988983, updateTime=1753502988983, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567701139607, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1753502988982, updateTime=1753502988982, creator=18614031015, updator=18614031015)])], journalTitle=科技导报, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Science & Technology Review, journalPhotoCn=wfghvu3bhh/dKxuZ+ucVHA==, journalPhotoEn=yjSfclmpNm7ihn9NbTZ69g==, journalFirstLetter=K, journalRecommend=null, journalNew=null, journalCollection=1, jcrJf=null, cjcrJf=0.91, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2018.05.003, detailUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/10.3981/j.issn.1000-7857.2018.05.003, pdfUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/PDF/10.3981/j.issn.1000-7857.2018.05.003, pdfUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/PDF/10.3981/j.issn.1000-7857.2018.05.003, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1520870400000, fullTextJson=null, articleText=null, reference=null)
收藏切换
克隆猴在中国率先突破,到底靠的是什么?
收藏切换
PDF下载
科技导报 | 科技纵横 2018,36(5): 23-27
收起
收藏切换
科技导报 |科技纵横 2018 , 36 (5) : 23 -27
克隆猴在中国率先突破,到底靠的是什么?
全屏
潘登科1,2
作者信息
    1. 中国农业科学院北京畜牧兽医研究所, 北京 100193;
    2. 四川省医学科学院四川省人民医院器官移植研究所, 成都 610072
作者简介:
潘登科,副研究员,研究方向为体细胞克隆、基因敲除克隆等,电子信箱:pandengke2002@163.com
Why first breakthrough of Monkeys cloned is in China
  • PAN Dengke1,2
  • Affiliations
      1. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
      2. Institute of Organ Transplantation, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, Chengdu 610072, China
    出版时间: 2018-03-13 doi: 10.3981/j.issn.1000-7857.2018.05.003
    文章导航
    收藏切换
    中国科学家孙强研究团队利用类似克隆羊多莉的体细胞克隆技术,在国际上率先获得了克隆猴的成功,这一成果于2018年1月25日发表在《Cell》上。本文回顾了克隆猴的技术流程和难点、体细胞克隆动物简史及国内外克隆猴不成功的历史,点评了克隆猴成功的关键和意义,指出需要更多的实验室来推动该技术的优化。
    克隆动物  /  克隆猴  /  体细胞核移植
    Scientists in China have produced the first cloned primates by a technique similar to the one used to clone Dolly the sheep and nearly two dozen other species. The breakthrough was published in Cell on 25 January. This review described the techniques process and a brief history of cloning animal. The history failed to produce live primates until now. The group of Sun Qiang optimized reprogramming developed by other groups. One trick was to undo chemical modifications in the DNA that occur when embryonic cells turn into specialized cells. The success of cloned monkey offer some significant advantages to study human neuropathy model. More Labs are needed to promote the optimization of the technology.
    cloned animal  /  cloned monkey  /  somatic cell nuclear transfer
    潘登科. 克隆猴在中国率先突破,到底靠的是什么?. 科技导报, 2018 , 36 (5) : 23 -27 . DOI: 10.3981/j.issn.1000-7857.2018.05.003
    PAN Dengke. Why first breakthrough of Monkeys cloned is in China[J]. Science & Technology Review, 2018 , 36 (5) : 23 -27 . DOI: 10.3981/j.issn.1000-7857.2018.05.003

      国家重点基础研究发展计划(973计划)项目(2015CB554103)

    参考文献 引证文献
    排序方式:
    2018年第36卷第5期
    PDF下载
    334
    123
    引用本文
    BibTeX
    文章信息
    doi: 10.3981/j.issn.1000-7857.2018.05.003
    • 接收时间:2018-02-10
    • 首发时间:2018-03-28
    • 出版时间:2018-03-13
    补充材料
    相关文章
    文章信息
    作者
    出版历史
    • 收稿日期:2018-02-10
    • 修回日期:2018-03-10
    基金
    作者信息
    参考文献
    分享链接
    https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2018.05.003
    分享至
    全文二维码

    扫描看全文

    引用本文
    BibTeX
    本文的引用情况
    2种不同金属材料的力学参数

    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
    关闭全屏