Article(id=1242136548997669133, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242136541515030780, articleNumber=null, orderNo=9, doi=10.3981/j.issn.1000-7857.2017.23.004, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1511539200000, receivedDateStr=2017-11-25, revisedDate=1512403200000, revisedDateStr=2017-12-05, acceptedDate=null, acceptedDateStr=null, onlineDate=1513392153367, onlineDateStr=2017-12-16, pubDate=1513094400000, pubDateStr=2017-12-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1513392153367, onlineIssueDateStr=2017-12-16, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774078031058, creator=sys-migrate, updateTime=1774078031058, updator=sys-migrate, issue=Issue{id=1242136541515030780, tenantId=1146029695717560320, journalId=1146031591421210625, year='2017', volume='35', issue='23', pageStart='1', pageEnd='112', issueExtLink='null', onlineDate='null', pubDate='1513094400000', pubDateStr='2017-12-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774078029275, creator='sys-migrate', updateTime=1774078029275, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=28, endPage=32, ext={EN=ArticleExt(id=1242136552478945522, articleId=1242136548997669133, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Cryo-electron microscopy:Commentary on the 2017 Nobel Prize in Chemistry, columnId=1242116903087440448, journalTitle=Science & Technology Review, columnName=Spescial Issues, runingTitle=null, highlight=null, articleAbstract=The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank and Richard Henderson for their contributions to the development of cryo-electron microscopy (cryo-EM) in determining the solution structures of biomolecular assemblies. In this article, we briefly introduce the history of cryo-EM and comment on the essential roles these three scientists have played in realizing this cutting-edge technique. We also present a summary of recent research breakthroughs that were made by Chinese scientists., authors=MA Chengying, GAO Ning, authorsList=MA Chengying, GAO Ning, authorCompany=State Key Laboratory of Membrane Biology;Peking-Tsinghua Joint Center for Life Sciences;School of Life Sciences, Peking University, Beijing 100871, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=mHfE8nj2DegMOXZ6lRw8UQ==, pdfFileSize=1371205, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242136550285320475, articleId=1242136548997669133, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=冷冻电子显微技术——2017年度诺贝尔化学奖成果简析, columnId=1242116902361830275, journalTitle=科技导报, columnName=专题论文, runingTitle=null, highlight=null, articleAbstract=2017年度诺贝尔化学奖授予瑞士洛桑大学的Jacques Dubochet、美国哥伦比亚大学的Joachim Frank和英国MRC分子生物学实验室的Richard Henderson 3位科学家。本文简要介绍冷冻电镜的发展历史、3位诺贝尔奖获得者在冷冻电镜技术发展过程中的贡献以及国际和国内的最新研究进展。, authors=马成英, 高宁, authorsList=马成英, 高宁, authorCompany=膜生物学国家重点实验室;北京大学-清华大学联合生命科学中心;北京大学生命科学学院, 北京 100871, correspAuthors=null, authorNote=马成英,博士后,研究方向为生物大分子结构与功能,电子信箱:mcy0916@163.com, correspAuthorsNote=高宁(通信作者),教授,研究方向为细胞内大型蛋白-核酸复合物形成的分子机器的精细结构及工作分子机制,电子信箱:gaon@pku.edu.cn, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=D6VxD5ywF2PIv8X9qoJp3A==, pdfFileSize=1371205, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, 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