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2. College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China;
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2. 华中农业大学植物科学技术学院, 武汉 430070;
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科技导报
| 专题论文 2016, 34(22): 68-74
基于抗体的小麦赤霉病抗性研究进展
全屏
廖玉才, 李和平
作者信息
Recent progress on antibody-based resistance against Fusarium head blight pathogens in wheat
LIAO Yucai, LI Heping
Affiliations
出版时间: 2016-11-28
doi: 10.3981/j.issn.1000-7857.2016.22.009
文章导航
由镰刀菌引起的小麦赤霉病,不仅降低产量和品质,所形成的真菌毒素还会影响食品安全。植物缺乏高抗小麦赤霉病的资源,因此从动物中筛选、分离抗病抗体及其基因,可为培育植物抗病品种提供新种质,也拓展了开发研究新抗源的渠道。抗病抗体能特异靶向真菌蛋白、抑制抗原的功能;抗体与抗菌肽和顺式表达调控元件结合,使病菌能诱导抗体融合蛋白在镰刀菌侵染小麦的颖壳高效表达,从而有效抑制病菌侵入、扩展及毒素积累。本文综述抗病抗体的抗原类型、抗病抗体及其融合蛋白在体外和植物中的表达以功能、抗原基因结构与功能、抗体抗病机理的研究进展。
抗体介导的抗病性
/
小麦赤霉病
/
镰刀菌
/
膜蛋白
/
乙二醛氧化酶
/
真菌毒素
Wheat Fusarium head blight (FHB) causes the reduction of yields and the quality degradation, as well as the contamination of mycotoxins that are produced by FHB pathogens and enter into the food chains, thus posing a serious threat to humans and farm animals. Plant germplasm resources with natural resistance against wheat FHB are inadequate. Thus, the isolation of antibodies and their genes from animals provides new resistance resources for the improvement of FHB resistance in wheat, as a new approach for other plants that lack natural resistance germplasms against pests. A disease-resistance antibody can specifically target the highly conserved transmembrane glyoxal oxidase in Fusarium and inhibit its oxidative reaction. A combination of the disease-resistance antibody, the antifungal peptide (AFP) and the regulatory cis-elements for plant expression will generate the antibody-AFP fusions that can be induced by FHB pathogens on the infection organs of wheat; this pathogen-inducible expression can restrict the fungal spreading and the mycotoxin accumulation in wheat, which is similar to the active immunity in mammalians that have been vaccinated. This paper reviews recent research progresses on FHB pathogens for preparation of antigens, expression and functional characterization in vitro and in planta of disease-resistance antibodies and their antibody fusions, the structure and the function of an antigen-encoding gene, and the resistance mechanisms of disease-resistance antibodies.
antibody-mediated disease resistance
/
wheat Fusarium head blight
/
Fusarium pathogen
/
membrane protein
/
glyoxal oxidase
/
mycotoxin
廖玉才, 李和平.
基于抗体的小麦赤霉病抗性研究进展.
科技导报,
2016
, 34
(22)
: 68
-74
.
DOI: 10.3981/j.issn.1000-7857.2016.22.009
LIAO Yucai, LI Heping.
Recent progress on antibody-based resistance against Fusarium head blight pathogens in wheat[J].
Science & Technology Review ,
2016
, 34
(22)
: 68
-74
.
DOI: 10.3981/j.issn.1000-7857.2016.22.009
2016年第34卷第22期
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BibTeX
文章信息
doi: 10.3981/j.issn.1000-7857.2016.22.009
接收时间:2016-08-29
首发时间:2016-12-13
出版时间:2016-11-28
收稿日期:2016-08-29
修回日期:2016-10-28
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2016.22.009
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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