Article(id=1242134487639864280, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242134390566887892, articleNumber=null, orderNo=44, doi=10.3981/j.issn.1000-7857.2016.2.038, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1441900800000, receivedDateStr=2015-09-11, revisedDate=1447171200000, revisedDateStr=2015-11-11, acceptedDate=null, acceptedDateStr=null, onlineDate=1454555982870, onlineDateStr=2016-02-04, pubDate=1453910400000, pubDateStr=2016-01-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1454555982870, onlineIssueDateStr=2016-02-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774077539587, creator=sys-migrate, updateTime=1774077539587, updator=sys-migrate, issue=Issue{id=1242134390566887892, tenantId=1146029695717560320, journalId=1146031591421210625, year='2016', volume='34', issue='2', pageStart='1', pageEnd='332', issueExtLink='null', onlineDate='null', pubDate='1453910400000', pubDateStr='2016-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774077516449, creator='sys-migrate', updateTime=1774077516449, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=226, endPage=230, ext={EN=ArticleExt(id=1242134490588455880, articleId=1242134487639864280, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Genetic characteristics of Uyghur from different sample locations in Xinjiang, columnId=1242116810380743325, journalTitle=Science & Technology Review, columnName=Reviews, runingTitle=null, highlight=null, articleAbstract=To understand the genetic characteristics of Uyghur, 300 Uyghur that were born before 1955 were collected from 10 Uyghur residence locations for generations, and 30 SNP loci were employed for genetics research. Bayesian analysis was applied for their genetic structure by STRUCTURE 2.1. The results show that it was reasonable to divide the Uyghurs in Xinjiang into seven groups. UPGMA method was used for phylogenetic research by MEGA 5 based on the Fst date form between different regions in Xinjiang. Both results show that each population from 10 locations was different except those from Urumqi and Ili, Turpan and Attash, and Hami and Kashgar. In other words, almost every population of the Uyghurs in Xinjiang was independent from the genetic view, and this phenomenon may be explained by the historical effect of the silk road and geographic factors., authors=ZHOU Canlin¹, MA Qi², YAO Hua², WANG Li², WANG Tingting³, MA Yan³, SU Yinxia⁴, WANG Zhiqiang³, CHEN Kaixu, authorsList=ZHOU Canlin, MA Qi, YAO Hua, WANG Li, WANG Tingting, MA Yan, SU Yinxia, WANG Zhiqiang, CHEN Kaixu, authorCompany=1. Basic Medical College of Xinjiang Medical University, Urumqi 830054, China;
2. Key Laboratory of Xinjiang Metabolic Disease, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China;
3. Department of Occupational and Environmental Health, Xinjiang Medical University, Urumqi 830011, China;
4. Diabetes Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China;
5. College of Biology Science and Technology, Xinjiang University, Urumqi 830046, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=912aXpP7rOXspAKyvLWneA==, pdfFileSize=609386, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242134489556657081, articleId=1242134487639864280, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=新疆各地维吾尔族遗传特征分析, columnId=1242116809164390686, journalTitle=科技导报, columnName=综述文章, runingTitle=null, highlight=null, articleAbstract=为全面反映不同地区维吾尔族的遗传特点,收集10 个维吾尔族世居地区的300 名1955 年以前出生的非近亲维吾尔族作为研究对象,利用30 个SNP 位点对其进行人类遗传学特征的研究。通过STRUCTURE 2.1 软件进行贝叶斯分析的结果表明,新疆的维吾尔族分为7 个不同的群体更加合理。利用新疆不同地区之间的维吾尔族的SNP 数据计算的遗传距离,输入MEGA 5软件并使用UPGMA 法构建系统发生树,结果表明除了乌鲁木齐与伊犁、吐鲁番与阿图什、哈密与喀什彼此接近以外,其余地区各自为一个独立的群体。新疆不同地区的维吾尔族在遗传结构上,大部分比较独立,说明现代新疆的维吾尔族遗传结果受到了包括丝绸之路漫长的历史作用,同时也受到当地特殊的地理环境的影响。, authors=周璨林¹, 马琦², 姚华², 王黎², 王婷婷³, 马艳³, 苏银霞⁴, 王志强³, 陈开旭, authorsList=周璨林, 马琦, 姚华, 王黎, 王婷婷, 马艳, 苏银霞, 王志强, 陈开旭, authorCompany=1. 新疆医科大学基础医学院, 乌鲁木齐 830054;
2. 新疆医科大学第一附属医院, 新疆代谢性疾病重点实验室, 乌鲁木齐 830054;
3. 新疆医科大学公共卫生学院, 乌鲁木齐 830011;
4. 新疆医科大学第一附属医院糖尿病防治中心, 乌鲁木齐 830011;
5. 新疆大学生命科学与技术学院, 乌鲁木齐 830046, correspAuthors=null, authorNote=周璨林,副教授,研究方向为人类遗传学,电子信箱:zhou_canlin@163.com;马琦(共同第一作者),助理研究员,研究方向为糖尿病的遗传基础,电子信箱:1346510539@qq.com, correspAuthorsNote=姚华,教授,研究方向为人类代谢性疾病,电子信箱:yaohua01@sina.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=dXxm220YkB/PLziJdoYFfg==, pdfFileSize=609386, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=新疆自治区自然科学基金项目(2013211B49))}, authors=null, keywords=[Keyword(id=1242134489074316256, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242134487639864280, language=CN, orderNo=1, keyword=SNP), Keyword(id=1242134489313391590, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242134487639864280, language=CN, orderNo=1, 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