Article(id=1242133299041218948, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242133271409144070, articleNumber=null, orderNo=17, doi=10.3981/j.issn.1000-7857.2015.07.015, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1421596800000, receivedDateStr=2015-01-19, revisedDate=1425830400000, revisedDateStr=2015-03-09, acceptedDate=null, acceptedDateStr=null, onlineDate=1430727653293, onlineDateStr=2015-05-04, pubDate=1428854400000, pubDateStr=2015-04-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1430727653293, onlineIssueDateStr=2015-05-04, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774077256204, creator=sys-migrate, updateTime=1774077256204, updator=sys-migrate, issue=Issue{id=1242133271409144070, tenantId=1146029695717560320, journalId=1146031591421210625, year='2015', volume='33', issue='7', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1428854400000', pubDateStr='2015-04-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774077249620, creator='sys-migrate', updateTime=1774077249620, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=90, endPage=94, ext={EN=ArticleExt(id=1242133302065307893, articleId=1242133299041218948, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=Effect of Helicobacter pylori infection on gut microbiota, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=This paper studies the effect of Helicobacter pylori (Hp) infection on gut microbiota using fresh stool specimens collected from normal persons (Hp negative) and patients with Hp infection. Hp, E. coli O157, Lactobacillus, Enterococcus and Bifidobacterium were amplified by PCR. The expression of Hp was not found in Hp negative group, consistent with the 13C breath test. The expression of Lactobacillus, Enterococcus and Bifidobacterium in Hp negative group was higher than that in Hp infection group. There was no E. coli O157 in Hp negative group. The numbers of Lactobacillus, Enterococcus and Bifidobacterium were changed by Hp infection., authors=DONG Hongxia1, LIANG Hao1, MIN Min2, authorsList=DONG Hongxia, LIANG Hao, MIN Min, authorCompany=1. Department of Gastroenterology, Chinese PLA General Hospital, Beijing 100853, China;
2. Department of Gastroenterology, Chinese PLA 307 Hospital, Beijing 100071, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=mW1w7KvZQFJN7QVIp1x7gg==, pdfFileSize=1107098, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242133300802822384, articleId=1242133299041218948, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=幽门螺杆菌感染对肠道菌群的影响, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=为研究幽门螺杆菌(Helicobacter pylori,Hp)感染对肠道菌群的影响,收集Hp 阴性和Hp 感染(阳性)患者的粪便标本,选择Hp 和肠道菌群中具代表性的大肠杆菌O157、乳酸杆菌、肠球菌、双歧杆菌进行PCR 扩增。实验结果表明,Hp 阴性组中未见Hp 表达,与13C 呼气实验结果基本一致;Hp 阴性组中乳酸杆菌、肠球菌、双歧杆菌表达较高,而Hp 感染组中3 者表达较少;Hp 阴性组中未检测到大肠杆菌O157。幽门螺杆菌感染可改变肠道菌群中乳酸杆菌、肠球菌、双歧杆菌等菌落的数量。, authors=董红霞1, 梁浩1, 闵敏2, authorsList=董红霞, 梁浩, 闵敏, authorCompany=1. 中国人民解放军总医院消化科, 北京 100853;
2. 中国人民解放军307医院消化科, 北京 100071, correspAuthors=null, authorNote=董红霞,主治医师,研究方向为肠道菌群与疾病的关系,电子信箱:dhongxia20080808@163.com, correspAuthorsNote=梁浩,主任医师,研究方向为幽门螺杆菌感染引发的相关疾病,电子信箱:lianghao301@163.com, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=rx4Hk0YIenJF3CUED3QPJQ==, pdfFileSize=1107098, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=国家自然科学基金项目(81300277))}, authors=null, keywords=[Keyword(id=1242133300517609708, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=CN, orderNo=1, keyword=幽门螺杆菌), Keyword(id=1242133300601495789, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=CN, orderNo=1, keyword=肠道菌群), Keyword(id=1242133300685381871, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=CN, orderNo=1, keyword=菌群失调), Keyword(id=1242133301364863386, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=EN, orderNo=1, keyword=Helicobacter pylori), Keyword(id=1242133301440360860, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=EN, orderNo=1, keyword=gut microbiota), Keyword(id=1242133301511659762, tenantId=1146029695717560320, journalId=1146031591421210625, articleId=1242133299041218948, language=EN, orderNo=1, keyword=flora imbalance)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1125356956822126595, delFlag=0, nameCn=科技导报, nameEn=Science & Technology Review, nameHistory1=null, nameHistory2=null, issn=1000-7857, eissn=, cn=11-1421/N, coden=null, periodic=3, language=CN, oaType=0, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=wfghvu3bhh/dKxuZ+ucVHA==, journalPrice=null, startedYear=null, abbrevIsoEn=Sci Technol Rev, journalRemark=null, publicationField=null, createdTime=null, updatedTime=1774230116083, createdBy=null, updatedBy=13041195026, firstLetterCn=S, firstLetterEn=S, subjectCode=Natural Sciences, subjectName=自然科学, subjectCodeEn=Natural Sciences, subjectNameEn=null, picCn=wfghvu3bhh/dKxuZ+ucVHA==, picEn=yjSfclmpNm7ihn9NbTZ69g==, jcr=null, cjcr=null, exts=[JournalExt(id=1242774439910290156, language=CN, name=科技导报, nameHistory1=null, nameHistory2=null, managedBy=中国科学技术协会, sponsoredBy=中国科学技术协会, publishedBy=科技导报社, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/CN/home, createdTime=1774230116107, updatedTime=1774230116107, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/CN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.cast.org.cn/webm, submissionEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionReviewUrl=https://kjdbauthor.cast.org.cn/webm, submissionCeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, submissionAeEditorUrl=https://kjdbeditor.cast.org.cn/webm/, option={"copyright":""}), JournalExt(id=1242774439960621805, language=EN, name=Science & Technology Review, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=http://www.kjdb.org/EN/home, createdTime=1774230116119, updatedTime=1774230116119, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=http://www.kjdb.org/EN/column/column7.shtml, submissionAuthorUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionReviewUrl=https://kjdbauthor.manuscriptcloud.com/login, submissionCeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, submissionAeEditorUrl=https://kjdbeditor.manuscriptcloud.com/login, option={"copyright":""})], databaseList=null, tenantJournalId=1146031591421210625, websiteList=[Website(id=1146104741081231361, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/CN, language=CN, createTime=1751182263881, createBy=18614031015, updateTime=1751778001962, updateBy=18614031015, name=科技导报, tplId=1146099689490845704, title=科技导报, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1148021146403992296, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=articleTextType, value=kx, createTime=1751639170504, updateTime=1751639170504, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146378826469, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=banner, value=null, createTime=1751639170498, updateTime=1751639170498, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146366243556, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1751639170495, updateTime=1751639170495, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146395603687, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/CN/file/pic, createTime=1751639170502, updateTime=1751639170502, creator=18614031015, updator=18614031015), WebsiteProps(id=1148021146387215078, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146104741081231361, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1751639170500, updateTime=1751639170500, creator=18614031015, updator=18614031015)]), Website(id=1146105254833139715, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1146031591421210625, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/kjdb/EN, language=EN, createTime=1751182386363, createBy=18614031015, updateTime=1753500121937, updateBy=18614031015, name=科技导报, tplId=1146101810881728533, title=Science & Technology Review, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1155838567709528217, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=articleTextType, value=kx, createTime=1753502988984, updateTime=1753502988984, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567692750998, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=banner, value=null, createTime=1753502988980, updateTime=1753502988980, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567688556693, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=logo, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic?fileId=9GHSf7eGlIPH0Tv/OOdstA==, createTime=1753502988979, updateTime=1753502988979, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567705333912, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/kjdb/EN/file/pic, createTime=1753502988983, updateTime=1753502988983, creator=18614031015, updator=18614031015), WebsiteProps(id=1155838567701139607, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1146105254833139715, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1753502988982, updateTime=1753502988982, creator=18614031015, updator=18614031015)])], journalTitle=科技导报, weixinUrl=null, journalUrl=null, iacademicId=null, status=1, seqNo=null, journalTitleEn=Science & Technology Review, journalPhotoCn=wfghvu3bhh/dKxuZ+ucVHA==, journalPhotoEn=yjSfclmpNm7ihn9NbTZ69g==, journalFirstLetter=S, journalRecommend=null, journalNew=null, journalCollection=1, jcrJf=null, cjcrJf=0.91, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=null, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2015.07.015, detailUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/10.3981/j.issn.1000-7857.2015.07.015, pdfUrlCn=https://castjournals.cast.org.cn/joweb/kjdb/CN/PDF/10.3981/j.issn.1000-7857.2015.07.015, pdfUrlEn=https://castjournals.cast.org.cn/joweb/kjdb/EN/PDF/10.3981/j.issn.1000-7857.2015.07.015, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1428854400000, fullTextJson=null, articleText=null, reference=null)
收藏切换
幽门螺杆菌感染对肠道菌群的影响
收藏切换
PDF下载
科技导报 | 研究论文 2015,33(7): 90-94
收起
收藏切换
科技导报 | 研究论文 2015, 33(7): 90-94
幽门螺杆菌感染对肠道菌群的影响
全屏
董红霞1, 梁浩1, 闵敏2
作者信息
    1. 中国人民解放军总医院消化科, 北京 100853;
    2. 中国人民解放军307医院消化科, 北京 100071

通讯作者:

梁浩,主任医师,研究方向为幽门螺杆菌感染引发的相关疾病,电子信箱:lianghao301@163.com
Effect of Helicobacter pylori infection on gut microbiota
Affiliations
出版时间: 2015-04-13 doi: 10.3981/j.issn.1000-7857.2015.07.015
文章导航
收藏切换
为研究幽门螺杆菌(Helicobacter pylori,Hp)感染对肠道菌群的影响,收集Hp 阴性和Hp 感染(阳性)患者的粪便标本,选择Hp 和肠道菌群中具代表性的大肠杆菌O157、乳酸杆菌、肠球菌、双歧杆菌进行PCR 扩增。实验结果表明,Hp 阴性组中未见Hp 表达,与13C 呼气实验结果基本一致;Hp 阴性组中乳酸杆菌、肠球菌、双歧杆菌表达较高,而Hp 感染组中3 者表达较少;Hp 阴性组中未检测到大肠杆菌O157。幽门螺杆菌感染可改变肠道菌群中乳酸杆菌、肠球菌、双歧杆菌等菌落的数量。
幽门螺杆菌  /  肠道菌群  /  菌群失调
This paper studies the effect of Helicobacter pylori (Hp) infection on gut microbiota using fresh stool specimens collected from normal persons (Hp negative) and patients with Hp infection. Hp, E. coli O157, Lactobacillus, Enterococcus and Bifidobacterium were amplified by PCR. The expression of Hp was not found in Hp negative group, consistent with the 13C breath test. The expression of Lactobacillus, Enterococcus and Bifidobacterium in Hp negative group was higher than that in Hp infection group. There was no E. coli O157 in Hp negative group. The numbers of Lactobacillus, Enterococcus and Bifidobacterium were changed by Hp infection.
Helicobacter pylori  /  gut microbiota  /  flora imbalance
董红霞, 梁浩, 闵敏. 幽门螺杆菌感染对肠道菌群的影响. 科技导报, 2015 , 33 (7) : 90 -94 . DOI: 10.3981/j.issn.1000-7857.2015.07.015
DONG Hongxia, LIANG Hao, MIN Min. Effect of Helicobacter pylori infection on gut microbiota[J]. Science & Technology Review, 2015 , 33 (7) : 90 -94 . DOI: 10.3981/j.issn.1000-7857.2015.07.015
2015年第33卷第7期
PDF下载
484
85
引用本文
BibTeX
文章信息
doi: 10.3981/j.issn.1000-7857.2015.07.015
  • 接收时间:2015-01-19
  • 首发时间:2015-05-04
  • 出版时间:2015-04-13
补充材料
相关文章
文章信息
作者
出版历史
  • 收稿日期:2015-01-19
  • 修回日期:2015-03-09
基金
作者信息

通讯作者:

梁浩,主任医师,研究方向为幽门螺杆菌感染引发的相关疾病,电子信箱:lianghao301@163.com
参考文献
分享链接
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2015.07.015
分享至
全文二维码

扫描看全文

引用本文
BibTeX
本文的引用情况
2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏