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Therefore, they are widely investigated and used in various biomedical fields, such as bone and tooth repair and replacement, drug delivery, gene transfection and diagnostic imaging. The chemical composition, structure, crystallite size, morphology, and crystallinity of the synthetic calcium phosphate materials, which are strongly influenced by their preparation methods, play a decisive role in their applications. Therefore, to develop various synthetic methods for the desirable materials is important for their applications. This paper reviews recent research progress of our group in the preparation, characterization, properties and applications of calcium phosphate nanostructured materials, focusing on the preparation methods, including room-temperature synthesis, solvothermal/hydrothermal synthesis, microwave-assisted rapid synthesis, electrospinning, and phosphorus-containing biomolecules based synthesis, and their applications in drug delivery, protein adsorption and release, and bioimaging. The future research trends are also discussed., authors=QI Chao, ZHU Yingjie, WU Jin, CHEN Feng, authorsList=QI Chao, ZHU Yingjie, WU Jin, CHEN Feng, authorCompany=Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=vOoEg8na2yiIA/MuuYDiKQ==, pdfFileSize=3576317, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1242133139515056905, articleId=1242133136801342204, tenantId=1146029695717560320, journalId=1146031591421210625, language=CN, title=磷酸钙纳米材料的制备、性能及应用, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, 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科技导报
| 研究论文 2015, 33(4): 111-119
磷酸钙纳米材料的制备、性能及应用
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漆超, 朱英杰, 吴进, 陈峰
作者信息
通讯作者:
朱英杰,研究员,研究方向为纳米生物材料、微波快速合成纳米材料,电子信箱:y.j.zhu@mail.sic.ac.cn
Preparation, properties and applications of calcium phosphate nanostructured materials
Affiliations
出版时间: 2015-02-28
doi: 10.3981/j.issn.1000-7857.2015.04.019
文章导航
磷酸钙作为生物体硬组织中主要的无机成分,具有良好的生物相容性、生物活性及生物可降解性,广泛应用于骨组织与牙齿修复和替换、药物输运和控制释放、基因转染及诊断成像等生物医学领域。人工合成磷酸钙材料的组成、结构、尺寸、形貌和结晶度等特性均与材料的制备方法有关,且材料的这些特性对其应用起到决定性作用。因此,发展不同的方法制备出具有特定组成、结构、尺寸、形貌、结晶度和性能的磷酸钙纳米材料对其应用至关重要。本文综述近年来在磷酸钙纳米材料的制备、表征、性能和应用研究方面所取得的最新进展,讨论室温制备法、溶剂热/水热合成法、微波辅助快速合成法、静电纺丝法及含磷生物分子磷源合成法等制备方法,分析磷酸钙纳米材料的性能及其在药物装载和可控释放、蛋白质吸附及释放、生物成像等领域的应用,展望磷酸钙纳米材料研究领域的发展趋势。
磷酸钙
/
羟基磷灰石
/
纳米材料
/
药物载体
/
医学应用
As the important inorganic component of biological hard tissues, calcium phosphate materials have high biocompatibility, bioactivity and biodegradability. Therefore, they are widely investigated and used in various biomedical fields, such as bone and tooth repair and replacement, drug delivery, gene transfection and diagnostic imaging. The chemical composition, structure, crystallite size, morphology, and crystallinity of the synthetic calcium phosphate materials, which are strongly influenced by their preparation methods, play a decisive role in their applications. Therefore, to develop various synthetic methods for the desirable materials is important for their applications. This paper reviews recent research progress of our group in the preparation, characterization, properties and applications of calcium phosphate nanostructured materials, focusing on the preparation methods, including room-temperature synthesis, solvothermal/hydrothermal synthesis, microwave-assisted rapid synthesis, electrospinning, and phosphorus-containing biomolecules based synthesis, and their applications in drug delivery, protein adsorption and release, and bioimaging. The future research trends are also discussed.
calcium phosphate
/
hydroxyapatite
/
nanomaterials
/
drug delivery
/
biomedical application
漆超, 朱英杰, 吴进, 陈峰.
磷酸钙纳米材料的制备、性能及应用.
科技导报,
2015
, 33
(4)
: 111
-119
.
DOI: 10.3981/j.issn.1000-7857.2015.04.019
QI Chao, ZHU Yingjie, WU Jin, CHEN Feng.
Preparation, properties and applications of calcium phosphate nanostructured materials[J].
Science & Technology Review ,
2015
, 33
(4)
: 111
-119
.
DOI: 10.3981/j.issn.1000-7857.2015.04.019
2015年第33卷第4期
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引用本文
BibTeX
文章信息
doi: 10.3981/j.issn.1000-7857.2015.04.019
接收时间:2014-09-15
首发时间:2015-03-19
出版时间:2015-02-28
收稿日期:2014-09-15
修回日期:2014-10-26
通讯作者:
朱英杰,研究员,研究方向为纳米生物材料、微波快速合成纳米材料,电子信箱:y.j.zhu@mail.sic.ac.cn
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2015.04.019
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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