Article(id=1242133059437408880, tenantId=1146029695717560320, journalId=1146031591421210625, issueId=1242133055423455754, articleNumber=null, orderNo=4, doi=10.3981/j.issn.1000-7857.2015.03.002, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1409673600000, receivedDateStr=2014-09-03, revisedDate=1419264000000, revisedDateStr=2014-12-23, acceptedDate=null, acceptedDateStr=null, onlineDate=1425368159913, onlineDateStr=2015-03-03, pubDate=1423756800000, pubDateStr=2015-02-13, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1425368159913, onlineIssueDateStr=2015-03-03, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1774077199076, creator=sys-migrate, updateTime=1774077199076, updator=sys-migrate, issue=Issue{id=1242133055423455754, tenantId=1146029695717560320, journalId=1146031591421210625, year='2015', volume='33', issue='3', pageStart='1', pageEnd='128', issueExtLink='null', onlineDate='null', pubDate='1423756800000', pubDateStr='2015-02-13', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=3, issueType=-1, specialIssue=null, createTime=1774077198126, creator='sys-migrate', updateTime=1774077198126, updator='sys-migrate', preIssue=null, nextIssue=null, articleTotal=null, ext=null, issueFiles=null, downloadFileDto=null}, startPage=19, endPage=23, ext={EN=ArticleExt(id=1242133063308751484, articleId=1242133059437408880, tenantId=1146029695717560320, journalId=1146031591421210625, language=EN, title=High-efficience Domino reaction of synthesizing 5-(4-fluorophenyl)-11-(4-methoxybenoyl)-2,3,4,5-tetrahydro-1H -indolo[2,3-b ]quinolin-1-one compound and characterizing its crystal structure, columnId=1242116080374710456, journalTitle=Science & Technology Review, columnName=Articles, runingTitle=null, highlight=null, articleAbstract=The title compound of 5-(4-fluorophenyl)-11-(4-methoxy benoyl)-2,3,4,5-tetrahydro-1H -indolo[2,3-b ]quinolin-1-one has been synthesized by the reaction of simple and off-the-shalf 3-p-methoxyphenacylideneoxindole with 3-(4-fluorophenylamino) cyclohex-2-enone as raw material in the presence of EtONa in ethanol. The structure of title product is determined by single crystal X-ray diffraction. The crystal is monoclinic, space group Cc , with Mr =537.57 (containing a molecular DMF solvent), a =1.44352(3) nm, b =2.6027(3) nm, c =0.93423(8) nm, V =2.6917(4) nm3 , Z =4, D c =1.327 Mg/m3 , μ =0.093 mm-1 , F (000)=1128. The structure is solved by direct methods and refined by full-matrix least squares method to the final R =0.0631, R ω =0.1535. X-ray analysis reveals that the formation of the new nitrogen-bearing six-member heterocyclic ring in the crystal structure is a coplanar structure., authors=LU Qiuli1 , ZHU Xiaotong1 , ZHU Jie2 , authorsList=LU Qiuli, ZHU Xiaotong, ZHU Jie, authorCompany=1. School of Basic Education Sciences, Xuzhou Medical College, Xuzhou 221004, China;H -吲哚[2,3-b ]喹啉-1-酮化合物及其晶体结构表征, columnId=1146540929516700224, journalTitle=科技导报, columnName=研究论文, runingTitle=null, highlight=null, articleAbstract=使用简便、易得的3-(4-甲氧基苯甲酰亚甲基)羟吲哚和3-(4-氟苯基氨基)-2-环己烯-1-酮为原料,在乙醇钠和乙醇的共同作用下,一步合成得到5-(4-氟苯基)-11-(4-甲氧基苯基)-1H -吲哚[2,3-b ]喹啉-1-酮化合物。通过单晶X衍射法确定其结构,晶体属单斜晶系,空间群Cc ,分子量Mr =537.57(包含1 分子溶剂DMF),晶胞参数a =1.44352(3) nm,b =2.6027(3) nm,c =0.93423(8) nm,V =2.6917(4) nm3 ,Z =4,晶胞密度D c =1.327 Mg/m3 ,吸收系数μ =0.093 mm-1 ,单胞中电子的数目F (000)=1128。晶体结构用直接法解出,经全矩阵最小二乘法对原子参数进行修正,最终的偏离因子为R =0.0631,R ω =0.1535。在晶体结构中新形成的含氮六元杂环近似于平面结构。, authors=路秋丽1 , 朱晓彤1 , 朱婕2 , authorsList=路秋丽, 朱晓彤, 朱婕, authorCompany=1. 徐州医学院公共教育学院, 徐州221004;
科技导报
| 研究论文 2015, 33(3): 19-23
高效Domino反应合成5-(4-氟苯基)-11-(4-甲氧基苯基)-1
H -吲哚[2,3-
b ]喹啉-1-酮化合物及其晶体结构表征
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路秋丽1 , 朱晓彤1 , 朱婕2
作者信息
1. 徐州医学院公共教育学院, 徐州221004;
通讯作者:
朱晓彤,副教授,研究方向为杂环合成、结构分析,电子信箱:xiaotongzhu2@126.com
High-efficience Domino reaction of synthesizing 5-(4-fluorophenyl)-11-(4-methoxybenoyl)-2,3,4,5-tetrahydro-1H -indolo[2,3-b ]quinolin-1-one compound and characterizing its crystal structure
Affiliations
出版时间: 2015-02-13
doi: 10.3981/j.issn.1000-7857.2015.03.002
文章导航
使用简便、易得的3-(4-甲氧基苯甲酰亚甲基)羟吲哚和3-(4-氟苯基氨基)-2-环己烯-1-酮为原料,在乙醇钠和乙醇的共同作用下,一步合成得到5-(4-氟苯基)-11-(4-甲氧基苯基)-1H -吲哚[2,3-b ]喹啉-1-酮化合物。通过单晶X衍射法确定其结构,晶体属单斜晶系,空间群Cc ,分子量Mr =537.57(包含1 分子溶剂DMF),晶胞参数a =1.44352(3) nm,b =2.6027(3) nm,c =0.93423(8) nm,V =2.6917(4) nm3 ,Z =4,晶胞密度D c =1.327 Mg/m3 ,吸收系数μ =0.093 mm-1 ,单胞中电子的数目F (000)=1128。晶体结构用直接法解出,经全矩阵最小二乘法对原子参数进行修正,最终的偏离因子为R =0.0631,R ω =0.1535。在晶体结构中新形成的含氮六元杂环近似于平面结构。
Domino反应
/
吲哚[2,3-b]喹啉
/
晶体结构
The title compound of 5-(4-fluorophenyl)-11-(4-methoxy benoyl)-2,3,4,5-tetrahydro-1H -indolo[2,3-b ]quinolin-1-one has been synthesized by the reaction of simple and off-the-shalf 3-p-methoxyphenacylideneoxindole with 3-(4-fluorophenylamino) cyclohex-2-enone as raw material in the presence of EtONa in ethanol. The structure of title product is determined by single crystal X-ray diffraction. The crystal is monoclinic, space group Cc , with Mr =537.57 (containing a molecular DMF solvent), a =1.44352(3) nm, b =2.6027(3) nm, c =0.93423(8) nm, V =2.6917(4) nm3 , Z =4, D c =1.327 Mg/m3 , μ =0.093 mm-1 , F (000)=1128. The structure is solved by direct methods and refined by full-matrix least squares method to the final R =0.0631, R ω =0.1535. X-ray analysis reveals that the formation of the new nitrogen-bearing six-member heterocyclic ring in the crystal structure is a coplanar structure.
Domino reaction
/
indolo[2,3-b]quinoline
/
crystal structure
路秋丽, 朱晓彤, 朱婕.
高效Domino反应合成5-(4-氟苯基)-11-(4-甲氧基苯基)-1H -吲哚[2,3-b ]喹啉-1-酮化合物及其晶体结构表征.
科技导报,
2015
, 33
(3)
: 19
-23
.
DOI: 10.3981/j.issn.1000-7857.2015.03.002
LU Qiuli, ZHU Xiaotong, ZHU Jie.
High-efficience Domino reaction of synthesizing 5-(4-fluorophenyl)-11-(4-methoxybenoyl)-2,3,4,5-tetrahydro-1H -indolo[2,3-b ]quinolin-1-one compound and characterizing its crystal structure[J].
Science & Technology Review ,
2015
, 33
(3)
: 19
-23
.
DOI: 10.3981/j.issn.1000-7857.2015.03.002
2015年第33卷第3期
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文章信息
doi: 10.3981/j.issn.1000-7857.2015.03.002
接收时间：2014-09-03
首发时间：2015-03-03
出版时间：2015-02-13
收稿日期：2014-09-03
修回日期：2014-12-23
通讯作者:
朱晓彤,副教授,研究方向为杂环合成、结构分析,电子信箱:xiaotongzhu2@126.com
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2015.03.002
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2种不同金属材料的力学参数
科 属数 种数 占总种数比例 属 种数 占总种数比例 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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