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科技导报
| 研究论文 2015, 33(2): 35-38
SH 2
D 7基因及其编码蛋白的生物信息学分析
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杨华1,2 , 杨风琴1,2 , 廖国玲1,2 , 刘学英1,2
作者信息
1. 宁夏医科大学检验学院, 银川750004;
2. 宁夏检验医学研究所, 银川750004
Bioinformatic analysis of SH 2D 7 and its encoded protein
Affiliations
出版时间: 2015-01-28
doi: 10.3981/j.issn.1000-7857.2015.02.003
文章导航
为了对SH 2D 7 基因序列及其编码蛋白进行生物信息学分析,应用NCBI 数据库和ExPASy 等程序,对SH 2D 7 基因核苷酸序列进行了分析,并预测了其编码蛋白的理化性质及二级结构等。结果表明,SH 2D 7 基因定位于人类染色体15q25.1,包含了6 个外显子和5 个内含子。SH 2D 7 基因编码蛋白的功能主要涉及基因表达调控、信号传导等;分子量约为49.8 kD,等电点为5.99,是一种亲水蛋白,主要位于细胞核中,有35 个磷酸化位点及22 个抗原位点。
The bioinformatic software is used to predict the nucleotide sequence of SH 2D 7 and the second structure of its encoding protein. It is shown that SH 2D 7 is located on the human chromosome 15q25.1, containing six exons and five introns. SH 2D 7 protein is mainly involved in the regulation of the gene expression and the signal transduction. Its molecular weight is 49.8 kD and the isoelectric point is 5.99. SH 2D 7 is a hydrophilic protein mainly located in the nucleus and there are 35 phosphorylation sites and 22 epitopes bit in the SH 2D 7 protein sequence.
cancer
/
SH2D7
/
bioinformatic analysis
杨华, 杨风琴, 廖国玲, 刘学英.
SH 2D 7基因及其编码蛋白的生物信息学分析.
科技导报,
2015
, 33
(2)
: 35
-38
.
DOI: 10.3981/j.issn.1000-7857.2015.02.003
YANG Hua, YANG Fengqin, LIAO Guoling, LIU Xueying.
Bioinformatic analysis of SH 2D 7 and its encoded protein[J].
Science & Technology Review ,
2015
, 33
(2)
: 35
-38
.
DOI: 10.3981/j.issn.1000-7857.2015.02.003
2015年第33卷第2期
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文章信息
doi: 10.3981/j.issn.1000-7857.2015.02.003
接收时间:2014-07-07
首发时间:2015-02-09
出版时间:2015-01-28
收稿日期:2014-07-07
修回日期:2014-10-07
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2015.02.003
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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