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科技导报
| 专题论文 2014, 32(26): 42-46
中国肺癌的驱动基因研究进展
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钱晓燕, 石远凯, 韩晓红
作者信息
中国医学科学院北京协和医学院肿瘤医院肿瘤研究所内科; 抗肿瘤分子靶向药物临床研究北京市重点实验室, 北京 100021
通讯作者:
韩晓红,研究员,研究方向为抗肿瘤药物疗效评价及预后相关的分子标志物,电子信箱:hanxh@cicams.ac.cn;xiaohonghan@hotmail.com
Recent Advances in the Study of Driver Genes for Chinese Lung Cancer
Affiliations
出版时间: 2014-09-18
doi: 10.3981/j.issn.1000-7857.2014.26.005
文章导航
肺癌是中国发病率及死亡率最高的恶性肿瘤。肿瘤细胞在驱动基因的作用下持续生长,并对该驱动基因的抑制剂具有高敏感性。近年来,针对驱动基因的检测技术不断发展,相应的驱动基因靶向药物也层出不穷。本文主要从中国肺癌的驱动基因、驱动基因的检测及针对驱动基因的靶向治疗3 个方面进行综述,并展望中国肺癌驱动基因的应用前景。
Lung cancer is the leading morbidity and mortality malignant tumor in China. Cancer cells keep growing under the action of driver genes and are sensitive to driver gene inhibitors. Recent years have witnessed continuous developments of driver gene detection technology and driver gene-targeted drugs. This review focus on the driver genes in lung cancer, detection of driver genes and targeted therapy of driver genes, giving a glimpse of the application prospect of driver genes for Chinese patients with lung cancer.
lung cancer
/
driver genes
/
targeted therapy
钱晓燕, 石远凯, 韩晓红.
中国肺癌的驱动基因研究进展.
科技导报,
2014
, 32
(26)
: 42
-46
.
DOI: 10.3981/j.issn.1000-7857.2014.26.005
QIAN Xiaoyan, SHI Yuankai, HAN Xiaohong.
Recent Advances in the Study of Driver Genes for Chinese Lung Cancer[J].
Science & Technology Review ,
2014
, 32
(26)
: 42
-46
.
DOI: 10.3981/j.issn.1000-7857.2014.26.005
2014年第32卷第26期
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文章信息
doi: 10.3981/j.issn.1000-7857.2014.26.005
接收时间:2014-08-12
首发时间:2014-09-26
出版时间:2014-09-18
收稿日期:2014-08-12
修回日期:2014-08-18
通讯作者:
韩晓红,研究员,研究方向为抗肿瘤药物疗效评价及预后相关的分子标志物,电子信箱:hanxh@cicams.ac.cn;xiaohonghan@hotmail.com
https://castjournals.cast.org.cn/joweb/kjdb/CN/10.3981/j.issn.1000-7857.2014.26.005
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2种不同金属材料的力学参数
科 Family 属数 Number of genus 种数 Number of species 占总种数比例 Percentage of total species (%) 属 Genus 种数 Number of species 占总种数比例 Percentage of total species (%) 鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78 小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39 多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39 红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87 小菇属 Mycena 11 5.26 光柄菇属 Pluteus 5 2.39 红菇属 Russula 17 8.13 栓菌属 Trametes 5 2.39
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